Exploring an unchartered route across the inner mitochondrial membrane
No
Research
Hosts: Linda Sinclair, Ian Ganley and Tony Ly
Venue: MSI Small Lecture Theatre, SLS
Abstract:
Mitochondria play diverse roles in metabolism. Cellular metabolic efficiency and adaptation to environmental stress depend on carefully regulated transport of metabolites across the impermeable inner mitochondrial membrane. Consequently, dysregulated metabolite transport is associated with numerous metabolic disorders, including cancer.
Metabolite transport across the inner mitochondrial membrane is under the exquisite control of dedicated solute carrier proteins. Most mitochondrial solute carriers belong to the solute carrier 25 family (SLC25), which share a common transport mechanism but have different substrate specificities and regulatory mechanisms. Studying these metabolite transporters will help reveal how mitochondria are integrated in disease-relevant signalling and metabolic pathways. This talk will introduce our recent exploration of mitochondrial methylated amino acid (MeAA) transport and metabolism. I will discuss how and why MeAAs end up in mitochondria and explore the impact of mitochondrial MeAA metabolism on cell biology and cancer progression. Our findings may provide new opportunities for therapeutic targeting of mitochondrial uptake of modified amino acids in the future.
Bio:
Tom is a Junior Group Leader and CRUK Career Development Fellow at the CRUK Scotland Institute and University of Glasgow. He completed his PhD with Jon Lane at the University of Bristol and moved to Cologne for a postdoc in Thomas Langer’s lab at the Max Planck Institute for Biology of Ageing and CECAD. He established his lab in Glasgow in 2022. His research group explores how mitochondria are reprogrammed in tumours with an overall goal to target metabolic plasticity in cancer.
No
Yes
Joint Tayside Immunity Group and MRC Protein Phosphorylation and Ubiquitylation Seminar by Tom MacVicar, CRUK, Beatson Institute
Staff
United Kingdom
Vice Chancellor's East Asia Undergraduate Scholarship (September 2026)
£4,000
for the first year of study
Undergraduate
Application & Offer
- Hold an offer for an eligible Undergraduate programme at the University of Dundee.
- Undergraduate: full-time, on-campus programme (excludes Medicine, Dentistry and Health Sciences). Programme fee must be £21,800 or above.
- Please review the Key Facts and Terms & Conditions documents for details of exclusions.
Fee Status
- Hold International Fee Status, as determined by the University of Dundee (confirmed in your offer letter).
International College Dundee (ICD)
- Applicants from ICD are eligible if they meet all the above criteria. The scholarship will be applied upon progression to the University of Dundee.
Please carefully read the Vice-Chancellor's Key Facts and Terms and Conditions 2026-27 documents for further information.
The Key Facts and Terms & Conditions documents are also available online for students who begin their studies through International College Dundee (ICD) in the 2025/26 academic year. These students will be eligible for University of Dundee scholarships, in line with the criteria and values set out for the 2025/26 cycle.
Scholarships will be applied upon progression to the student’s main University of Dundee degree.
There is no separate application required for this scholarship. The University Admissions Team will automatically review the information you have provided to confirm your eligibility for the award.
Eligible schools
Scholarship type
Eligible entry dates
1 September 2026
Harnessing regulatory T cells to fight neuroinflammation
No
Research
Hosts: Andy Howden, Henry McSorley and Linda Sinclair
Venue: MSI Small Lecture Theatre, SLS
This seminar is funded by the Tayside Immunology Group, British Society of Immunology
Bio
Adrian Liston is Professor of Pathology at the Department of Pathology, University of Cambridge, Honorary Group Leader at the Babraham Institute, Equalities Fellow, Postgraduate Tutor for Welfare and Director-of-Studies at St Catharine's College, and Editor-in-Chief of Immunology & Cell Biology. Liston runs a biomedical research laboratory together with Dr James Dooley, Principal Research Associate. The Liston-Dooley laboratory currently works on understanding the regulation of immune responses in the tissues, in particular the brain. Prof Liston has been awarded fellowship to the Academy of Medical Sciences, the Francqui Chair, the Eppendorf Prize, a Wellcome Trust Investigator Award and three ERC grants, among other honours.
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Microsoft Teams Need help?
Meeting ID: 351 913 954 138 85
Passcode: XD79Lp3G
No
Yes
CSI Discovery Seminar by Professor Adrian Liston, University of Cambridge, Department of Pathology
Staff
United Kingdom