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Eight years ago it was discovered that the SIK subfamily of protein kinases suppress the production of the anti-inflammatory cytokine IL-10 by phosphorylating and activating CRTC3, co-activator of the transcription factor CREB.
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Eight years ago it was discovered that the SIK subfamily of protein kinases suppress the production of the anti-inflammatory cytokine IL-10 by phosphorylating and activating CRTC3, co-activator of the transcription factor CREB.
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Two life sciences researchers have been awarded Future Leaders Fellowships from UK Research and Innovation (UKRI).
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Tricia Cohen, co-founding Principal Investigator of the MRC Protein Phosphorylation Unit died from Lymphoma in August 2020. She was 76.
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Natalie Bamford, a Postdoctoral Research Assistant in the lab of Nicola Stanley-Wall, has been awarded a prestigious two-year EMBO Long-term fellowship.
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The three-year alliance will allow knowledge, skills and technology sharing, as well as two joint postdoctoral positions, in order to accelerate discoveries on molecular metabolic signalling in control of glucose homeostasis
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Elena Purlyte, a PhD student in Professor Dario Alessi’s lab in the MRC-PPU, has been issued with a commendation by the University Principal.
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Dr Sarah Coulthurst, deputy head of the Division of Molecular Microbiology, has had her Wellcome Trust Senior Research Fellowship renewed for a further five years.
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A new toolkit website has been launched to help in the fight against Covid-19.
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Despite the coronavirus lockdown, researchers from MRC PPU are continuing to attend online meetings, seminars and conferences to share ideas with researchers around the world.
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Researchers from the MRC-PPU have uncovered potential cross-talk between PINK1 and LRRK2 signalling pathways linked to Parkinson’s disease.
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A protocol for utilizing human peripheral blood neutrophils for research into the Parkinson’s disease associated LRRK2 kinase has been published.
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New research by Greg Findlay’s group in the MRC-PPU has identified a signalling system that controls embryonic stem cell development, which has implications for understanding how tissues form within the mammalian embryo.
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A new collaboration hopes to improve understanding of diseases such as Alzheimer's and Parkinson's.
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Megan Bergkessel and Leeanne McGurk have been awarded funding from the Springboard scheme of the Academy of Medical Sciences, which is designed to help early career researchers establish their independent research programmes.
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Esther Sammler has been awarded funding to continue research into Parkinson's disease.
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The School has welcomed three new group leaders in recent months. They are currently establishing their laboratories across three of our divisions.
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Professor David Lilley has been made a visiting professor at Nankai University in Tianjin, China. Nankai is one of the top 20 universities in China and is celebrating its 100th Anniversary this year.
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Researchers at the University of Dundee have discovered an enzyme they believe could be key to preventing Group A Streptococcus infections that cause more than 500,000 deaths worldwide each year.
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On October 1st 1969 Philip Cohen became a postdoc in Edmond Fischer’s at the University of Washington, Seattle, USA and started his research on protein phosphorylation.
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Hannah Tovell a PhD student in Dario Alessi lab working with Claire Crafter (AstraZeneca) and Alessio Ciulli and Andrea Testa in his lab have elaborated a compound termed SGK3-PROTAC1 that induces selective degradation of SGK3 protein kinase.