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Researchers in the Ciulli group report a first study describing the idea of a macrocyclic PROTAC. The research was published in the prestigious chemistry journal Angewandte Chemie.
Stories in School of Life Sciences
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On October 1st 1969 Philip Cohen became a postdoc in Edmond Fischer’s at the University of Washington, Seattle, USA and started his research on protein phosphorylation.
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Hannah Tovell a PhD student in Dario Alessi lab working with Claire Crafter (AstraZeneca) and Alessio Ciulli and Andrea Testa in his lab have elaborated a compound termed SGK3-PROTAC1 that induces selective degradation of SGK3 protein kinase.
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DEBRA is delighted to share that funding for a fourth year of the University of Dundee’s research into novel gene technology for treating Epidermolysis Bullosa (EB) has been agreed.
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Two academic entrepreneurs from the division of Biological Chemistry and Drug Discovery have made the final of the Converge Challenge 2019.
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School of Life Sciences researcher Professor David Horn will receive a £2.1 million Investigator Award from Wellcome to decode gene expression mechanisms in trypanosomes, pathogenic protozoa that cause a range of human and animal diseases.
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Dr Susan Wyllie, Head of the Mode of Action (MoA) group, has been promoted to tenure track Principal Investigator in the School.
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The University of Dundee has announced a new partnership with Eisai, one of the world’s leading research-based pharmaceutical companies.
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Ian Kelsall and Jiazhen Zhang, two postdoc’s in Philip Cohen’s lab, have discovered the function of HOIL-1.
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Around 60 aspiring entrepreneurs from across Scotland’s Universities are now through to the next stage of Scotland’s leading academic enterprise programme.
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An Alessi lab PhD student working closely with the Ciulli lab has published an improved HaloPROTAC method to induce post–translational knockdown of endogenous proteins.
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Professor Alessio Ciulli is recognised as one of a handful of key players world-wide in opening up and pushing forward this exciting field of research and development.
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Dr Robyn Hickerson and her team won the Research Staff Award at Venture 2019 competition.
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The findings challenge a dogma that has persisted for more than 30 years.
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Dr Greg Findlay from the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) has been awarded tenure.
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Scientists in the School have confirmed that a key cellular pathway that protects the brain from damage is disrupted in Parkinson’s patients, raising the possibility of new treatments for the disease.
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PhD students from the MRC PPU took part in the Biotechnology YES 2018 entrepreneurial competition.
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The success of a University of Dundee collaboration will be celebrated this week.
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Kim Dale and Miratul Muqit have been promoted to Personal Chair (Professor) as part of the 2018 Annual Review process for academic staff.
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A group of scientists at the University of Dundee have been honoured for putting an end to a promising piece of research.