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Researchers in the Ciulli group report a first study describing the idea of a macrocyclic PROTAC. The research was published in the prestigious chemistry journal Angewandte Chemie.
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Researchers in the Ciulli group report a first study describing the idea of a macrocyclic PROTAC. The research was published in the prestigious chemistry journal Angewandte Chemie.
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Researchers at the University of Dundee have discovered an enzyme they believe could be key to preventing Group A Streptococcus infections that cause more than 500,000 deaths worldwide each year.
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Hannah Tovell a PhD student in Dario Alessi lab working with Claire Crafter (AstraZeneca) and Alessio Ciulli and Andrea Testa in his lab have elaborated a compound termed SGK3-PROTAC1 that induces selective degradation of SGK3 protein kinase.
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DEBRA is delighted to share that funding for a fourth year of the University of Dundee’s research into novel gene technology for treating Epidermolysis Bullosa (EB) has been agreed.
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School of Life Sciences researcher Professor David Horn will receive a £2.1 million Investigator Award from Wellcome to decode gene expression mechanisms in trypanosomes, pathogenic protozoa that cause a range of human and animal diseases.
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Ethiopia's National Barley Research Program Coordinator, has started a PhD in Dundee.
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Prof. Grahame Hardie and two of his co-workers, Diana Vara-Ciruelos and Fiona Russell, have published a review in the journal Open Biology.
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The University of Dundee has announced a new partnership with Eisai, one of the world’s leading research-based pharmaceutical companies.
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Ian Kelsall and Jiazhen Zhang, two postdoc’s in Philip Cohen’s lab, have discovered the function of HOIL-1.
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Scientists at the University of Dundee and Boehringer Ingelheim have made an important first stride toward drugging undruggable cancer targets.
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Researchers have revealed atomic-resolution images of how an E3 ubiquitin ligase enzyme latches on to its protein partners.
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An Alessi lab PhD student working closely with the Ciulli lab has published an improved HaloPROTAC method to induce post–translational knockdown of endogenous proteins.
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Latest research from Professor Kim Dale and collaborators has uncovered further knowledge into the developmental segmentation process which may also impact on our understanding of diseases such as cancer.
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Researchers at the Centre for Gene Regulation and Expression have discovered that PI3KCA oncogene changes how cells require their protein contents to be made.
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Researchers from the Schools of Life Sciences and Medicine have been awarded a £275,000 grant from Diabetes UK.
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The University of Dundee Drug Discovery Unit announced a partnership with Takeda, Japan’s largest pharmaceutical company.
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Dr. Mattie Christine Pawlowic has opened a new research laboratory jointly in the Division of Biological Chemistry and Drug Discovery (BCDD) and our new Wellcome Centre for Anti-Infectives Research (WCAIR).
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A University of Dundee scientist has been awarded €2 million to study how cells respond to infection.
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New work from Professor Kate Storey’s laboratory has recently been published in eLife.
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Maintenance of tissues requires a delicate balance between a number of processes such as the increase in the number of cells (proliferation) and the type of cells they become (differentiation).