Summer lab-based traineeship supervisors in Life Sciences
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The following supervisors are offering places to summer students of the Vacation Scholarship Programme.
Division of Biological Chemistry and Drug Discovery
| Name | Research interests |
|---|---|
| Professor Alessio Ciulli | Chemical and Structural Biology of Targeted Protein Degradation |
| Professor Sir Michael Ferguson | Professor Sir Michael is an expert on the biochemistry of protozoan parasites, the molecular details of infection in general and on drug discovery for infectious and non-infectious diseases. He serves on the boards of the Medicines for Malaria Venture and UK Biobank and previously of the Wellcome Trust. |
| Professor David Gray | Molecular Pharmacology and Compound Screening |
| Dr Robyn Hickerson | |
| Professor Kevin Read | Drug discovery, lead optimisation and preclinical development |
| Professor David Horn | Professor Horn’s research focusses on Neglected Tropical Diseases, caused by trypanosomes. Areas of expertise include drug resistance, drug development, gene expression control, immune evasion, molecular genetics, and high-throughput genetic screens. |
| Professor Ian Gilbert | Design and synthesis of potential therapeutic agents |
| Professor Mark Field | Professor Field’s work principally exploits the parasitic protozoan Trypanosoma brucei and efforts to leverage genomics and proteomics resources to provide insight into virulence mechanisms and basic cell biology, with specific interests in protein transport systems and nuclear organisation. He has interests in bioinformatics, graphic design, functional genomics and eukaryotic evolutionary biology. |
| Dr Mattie Pawlowic | Cryptosporidium, molecular parasitology, drug discovery |
| Dr Susan Wyllie | Kinetoplastid Biology |
| Dr William Farnaby | The Farnaby group is interested in using induced proximity chemistry to understand and treat diseases of the central nervous system. |
Division of Cell and Developmental Biology
| Name | Research interests |
|---|---|
| Professor Kim Dale | Establishing the vertebrate embryonic body plan |
| Dr Jens Januschke | Dynamics of cell polarisation |
| Professor Carol MacKintosh | Diabetes and cancer as disorders of 'signal multiplexing' in the vertebrate animals |
| Dr Leeanne McGurk | How does RNA biogenesis control motor neuron disease? |
| Dr David Murray | Understanding the basic molecular mechanics in the formation of sub-cellular structures |
| Professor Inke Nathke | From molecules to tissue architecture |
| Professor Kees Weijer | Cell-cell signalling and chemotactic cell movement during development |
Division of Cell Signalling and Immunology
| Name | Research interests |
|---|---|
| Professor Simon Arthur | Signaling networks that control inflammation |
| Dr Henry McSorley | Immunological interactions with helminth parasites |
| Professor Doreen Cantrell | T-lymphocyte signal transduction |
| Professor Hari Hundal | Hormonal, nutrient and stress-mediated modulation of fuel and energy metabolism |
| Dr Ignacio Moraga Gonzalez | Cytokine engineering |
Division of Computational Biology
| Name | Research interests |
|---|---|
| Professor Geoffrey Barton | Protein and nucleic acid sequence analysis and function prediction |
| Dr Rastko Sknepnek | Computational soft condensed matter and biophysics |
| Dr Gabriele Schweikert | |
| Professor Ulrich Zachariae | Computational Biophysics and Drug Discovery |
MRC Protein Phosphorylation and Ubiquitylation Unit
| Name | Research interests |
|---|---|
| Professor Dario Alessi | Professor Alessi is a biochemical engineer whose research focuses on opening up our understanding of human health and disease. Much of his current work focuses on understanding a gene involved in Parkinson’s called LRRK2 and aims to exploit findings on this to develop improved ways to better diagnose and treat the disease. |
| Dr Paul Davies | |
| Dr Greg Findlay | Embryonic Stem Cell Signaling Modules |
| Professor Miratul Muqit | Elucidation of the PINK1 signaling pathway in Parkinson’s disease |
| Dr Esther Sammler | Parkinson’s disease |
| Professor Gopal Sapkota | Untangling the TGFβ and Wnt signalling networks in cells, development and human diseases |
| Dr Amos Liang | |
| Professor Ian Ganley | Molecular analysis of autophagy |
| Professor John Rouse | Control of chromosome stability and DNA repair in health and disease |
| Professor Karim Labib | Chromosome replication and genome integrity |
| Dr Kirby Swatek | Ubiquitin and ubiquitin-like proteins in the immune system |
| Professor Sir Philip Cohen | Signaling Networks in the Innate Immune System |
| Professor Satpal Virdee | Chemical Biology Approaches for Studying The Ubiquitin System |
| Professor Yogesh Kulathu | Signal transduction mediated by the posttranslational modification of proteins in the maintenance of protein and cellular homeostasis |
| Dr Mahima Swamy | Immune interactions at the intestinal epithelium |
| Dr Adrien Rousseau | Signalling pathways controlling proteasome homeostasis |
Division of Molecular Microbiology
| Name | Research interests |
|---|---|
| Professor Nicola Stanley-Wall | Understanding the molecular mechanism of biofilm formation |
| Dr Helge Dorfmueller | Investigation of streptococcal cell wall biogenesis and glycoconjugate vaccine development |
| Dr Megan Bergkessel | Regulatory mechanisms operating during bacterial growth arrest and persistence |
| Professor Sarah Coulthurst | Microbial competition and bacterial protein secretion systems |
Division of Plant Sciences
| Name | Research interests |
|---|---|
| Dr Jorunn Bos | |
| Dr Davide Bulgarelli | Structure, function and host control of the plant microbiota |
| Professor Claire Halpin | |
| Dr Piers Hemsley | Regulation of protein function in plants by S-acylation |
| Dr Edgar Huitema | Mechanisms of virulence acquisition during Phytophthora-host associations |
| Dr Sarah McKim | Developmental biology of plant architecture |
| Professor Gordon Simpson | RNA and Development |
| Dr Ingo Hein | Plant Pathogen Co-evolution |
| Professor Paul Birch | Plant pathogen interactions |
| Professor Robbie Waugh | Crop Genomics |
| Dr Martin Balcerowicz | Dr Balcerowicz is a plant molecular biologist with a specific interest in how plants perceive and react to their environment, particularly to light and temperature signals. His areas of expertise include plant development, plant genetics, light signalling, temperature sensing and plant responses to climate change. |
Centre for Gene Regulation and Expression
| Name | Research interests |
|---|---|
| Professor Angus Lamond | Nuclear structure proteomics and gene expression |
| Dr Constance Alabert | DNA replication in the context of chromatin – Implications for human diseases |
| Professor Ronald Hay | Role of ubiquitin and ubiquitin-like proteins in transcriptional regulation |
| Professor Tom Owen-Hughes | Chromatin structure and gene regulation |
| Dr Fede Pelisch | Mechanisms of Meiotic Chromosome Segregation and its Regulation by Post-Translational Modifications |
| Dr Kasper Rasmussen | Investigating the regulation and function of DNA methylation in hematopoiesis |
| Professor Jason Swedlow | Mitotic chromosome dynamics |
| Professor Tomoyuki Tanaka | Mechanisms ensuring proper chromosome segregation in mitosis |
| Dr Tony Ly | Proliferation control in health and disease |
| Professor Julian Blow | How DNA replication is organised and controlled to ensure precise chromosome duplication |