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Eight years ago it was discovered that the SIK subfamily of protein kinases suppress the production of the anti-inflammatory cytokine IL-10 by phosphorylating and activating CRTC3, co-activator of the transcription factor CREB.
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Eight years ago it was discovered that the SIK subfamily of protein kinases suppress the production of the anti-inflammatory cytokine IL-10 by phosphorylating and activating CRTC3, co-activator of the transcription factor CREB.
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Two life sciences researchers have been awarded Future Leaders Fellowships from UK Research and Innovation (UKRI).
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Tricia Cohen, co-founding Principal Investigator of the MRC Protein Phosphorylation Unit died from Lymphoma in August 2020. She was 76.
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The three-year alliance will allow knowledge, skills and technology sharing, as well as two joint postdoctoral positions, in order to accelerate discoveries on molecular metabolic signalling in control of glucose homeostasis
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Elena Purlyte, a PhD student in Professor Dario Alessi’s lab in the MRC-PPU, has been issued with a commendation by the University Principal.
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A new toolkit website has been launched to help in the fight against Covid-19.
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Despite the coronavirus lockdown, researchers from MRC PPU are continuing to attend online meetings, seminars and conferences to share ideas with researchers around the world.
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Researchers from the MRC-PPU have uncovered potential cross-talk between PINK1 and LRRK2 signalling pathways linked to Parkinson’s disease.
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A protocol for utilizing human peripheral blood neutrophils for research into the Parkinson’s disease associated LRRK2 kinase has been published.
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New research by Greg Findlay’s group in the MRC-PPU has identified a signalling system that controls embryonic stem cell development, which has implications for understanding how tissues form within the mammalian embryo.
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A new collaboration hopes to improve understanding of diseases such as Alzheimer's and Parkinson's.
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Esther Sammler has been awarded funding to continue research into Parkinson's disease.