Centre for Targeted Protein Degradation

The Centre for Targeted Protein Degradation (CeTPD) is bolstering the University of Dundee’s world-leading position in a field that is revolutionising drug discovery.

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Targeted protein degradation

CeTPD

Targeted protein degradation co-opts the cell’s natural disposal systems to remove disease-causing proteins and is applicable to diverse therapeutic areas including oncology, dermatology, immunology, neuroscience and respiratory diseases.

This entirely new approach is revolutionising drug discovery by making the treatment of diseases previously thought to be undruggable a reality.

CeTPD is part of the University’s School of Life Sciences, one of the UK’s top institutions for research into biological sciences.

Dundee researchers and teams led by Professor Alessio Ciulli have previously revealed fundamental insights into the working of the degrader molecules that they have designed and that are used across the globe. Collaborations with pharma companies Boehringer Ingelheim and Almirall amongst others are helping to advance the field, while the biopharmaceutical company Amphista Therapeutics is a University of Dundee spin-out of the Ciulli Lab.

Our new translational research centre will build on this established excellence to innovate groundbreaking science and accelerate translation by developing and inspiring the next generation of scientists and leaders.

Professor Alessio Ciulli in a lab with researchers

Professor Alessio Ciulli

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School of Life Science’s Professor Alessio Ciulli was amongst a selected group of world’s leading expert scientists and key opinion leaders who spoke at the Galien Forum on October 24, 2019, at the Alexandria Center in New York City.

Published on 29 October 2019