Centre for Targeted Protein Degradation
The Centre for Targeted Protein Degradation (CeTPD) is bolstering the University of Dundee’s world-leading position in a field that is revolutionising drug discovery.
Targeted protein degradation
Targeted protein degradation co-opts the cell’s natural disposal systems to remove disease-causing proteins and is applicable to diverse therapeutic areas including oncology, dermatology, immunology, neuroscience and respiratory diseases.
This entirely new approach is revolutionising drug discovery by making the treatment of diseases previously thought to be undruggable a reality.
CeTPD is part of the University’s School of Life Sciences, one of the UK’s top institutions for research into biological sciences.
Dundee researchers and teams led by Professor Alessio Ciulli have previously revealed fundamental insights into the working of the degrader molecules that they have designed and that are used across the globe. Collaborations with pharma companies Boehringer Ingelheim and Almirall amongst others are helping to advance the field, while the biopharmaceutical company Amphista Therapeutics is a University of Dundee spin-out of the Ciulli Lab.
Our new translational research centre will build on this established excellence to innovate groundbreaking science and accelerate translation by developing and inspiring the next generation of scientists and leaders.
Professor Alessio Ciulli
Stories
News
Review of the Year 20212 took place last week with the Dean, Julian Blow sharing the highlights of activity within the School from 2022.
Press release
University of Dundee spinout Amphista Therapeutics has received a boost in its efforts to develop new drugs for neurogenerative diseases such as dementia.
Press release
A successful collaboration between the University of Dundee and pharmaceutical company Eisai Co Ltd aiming to create innovative new cancer drugs has been extended for a further three years.
Press release
An international collaboration, featuring scientists from the University of Dundee, has made a breakthrough they hope will help futureproof a revolutionary new field of drug discovery by preventing resistance in cancer therapy.
Press release
Scientists have designed a novel molecule capable of destroying an as-yet undruggable cancer-causing protein – and are making it available for researchers around the world to use in their own work, free of charge
Press release
University of Dundee spinout Amphista Therapeutics has been designated as one of the world’s most promising biotechnology companies.
Press release
Researchers from the University of Dundee have discovered a small molecule that helps to eliminate a Parkinson’s disease-causing protein
Feature
Early career researchers in the School have received support from the Scottish Universities Life Sciences Alliance (SULSA) to establish new life sciences networks by providing funds towards the running of a network event.