Dr Andrei Pisliakov
+44 (0)1382 388758
Andrei Pisliakov obtained his first degree (in Physics) from the Belarus State University in Minsk and PhD (in Theoretical Chemistry) from the Technical University of Munich, Germany.
In 2004, he moved to California for a postdoc in the lab of Graham Fleming at Berkeley. Andrei carried out theoretical work in femtosecond spectroscopy, with applications to ultrafast energy transfer in photosynthetic complexes. Driven by a strong interest in biology and “real world” applications of physical concepts, in 2005 Andrei joined the lab of Arieh Warshel at the University of Southern California in Los Angeles. His research there focused on simulations of proton transfer in biological systems and enzyme catalysis. Between 2009 and 2013, Andrei held an FPR fellow and a contract researcher positions in the group of Yuji Sugita at the RIKEN Institute in Japan. During that period he extensively used supercomputers for large-scale simulations of membrane proteins and established collaborations with leading structural biology and biochemistry groups. Andrei joined the University of Dundee as a Senior Lecturer & Dundee Fellow in July 2013.
Theoretical and Computational Biophysics
- Use (and develop new) methods for biomolecular simulations:
- atomistic molecular dynamics (MD)
- quantum mechanics/molecular mechanics (QM/MM)
- empirical valence bond (EVB)
- hierarchical multiscale methods
- Apply to:
- membrane proteins
- proton transfer in biology
- bioenergetics: proton and ion pumps, respiratory enzymes, photosynthetic complexes
Researchers at the University of Dundee have identified novel interaction sites on the mRNA Capping Enzyme that are essential for its activity.
The mechanism of a protein which transports ammonium across cell membranes has been discovered in research led at the University of Strathclyde, in collaboration with the University of Dundee and the Université Libre de Bruxelles.