Completed Trials at TCTU
We have highlighted some of our completed trials, to demonstrate breadth of disciplines TCTU has worked across and the range of support TCTU can provide.
On this page
| Name | Description | Further information |
|---|---|---|
| PROTEAN | Proteomic Profiling of Oesophageal and Gastroesophageal Junction Adenocarcinoma Neoantigens | |
| INFLUENCE | A prospective randomised study comparing indocyanine green (ICG) fluorescence combined with a standard tracer versus ICG alone for sentinel lymph node (SLN) detection in early breast cancer. | INFLUENCE trial information |
| PIVUC | A two-stage preliminary investigation of the visual and histological changes to healthy volunteer skin from single and repetitive exposure to virucidal Krypton-Chloride (KrCl) Far-UVC-emitting excimer lamps. | PIVUC trial information |
| INCOGNITO | INvestigating COPD Outcomes, Genomics and Neutrophilic Inflammation with Tiotropium and Olodaterol. | INCOGNITO trial information |
| MUSIC | Investigating the mechanism of inhaled corticosteroids associated pneumonia by longitudinal characterisation of the airway microbiome in patients with severe COPD. | MUSIC trial information |
| ArchWire RaCE | A randomised clinical trial which aims to compare the clinical effectiveness of FireWire archwires to Copper Nickel Titanium (CNiTi) archwires. | ArchWire RaCE trial information |
| STOP COVID-19 | Research to test the effectiveness of a new anti-inflammatory drug, Brensocatib, to improve symptoms and reduce hospitalisation for people with COVID-19. | STOP COVID-19 trial information |
| REACH | Testing and treating people receiving methadone for Hepatitis C in community pharmacies. | REACH trial information |
| ADVANCE | Investigating the best way to provide treatment for people who inject drugs infected with Hepatitis C virus. | ADVANCE trial information |
| SUSSED | Understanding barriers to increasing physical activity in chronic pain. | SUSSED trial information |
| LACE | Leucine and ACE inhibitors as therapies for sarcopenia: a two by two factorial randomised placebo-controlled trial. | LACE trial information |
| MULTIPROS | Assessing the readability of pre-biopsy MRI in correctly predicting the grade and aggressiveness of prostate cancer in 600 men. | MULTIPROS trial information |
| RAINDroP | Randomised controlled pilot to identify people with iron deficiency who do not respond to oral iron supplementation. | RAINDroP trial information |
| ERADICATE Hep C | Eradicate Hepatitis C Virus: A pilot of treatment as prevention in active drug users. | ERADICATE Hep C trial information |
| SuperDOT-C | Pharmacy-led HCV therapy versus conventional treatment pathways for HCV positive patients receiving daily OST. | SuperDOT-C trial information |
| ECLS Study | The largest randomised trial conducted using biomarkers for the early detection of lung cancer, in over 12,000 Scottish high-risk smokers. | ECLS study information |
| BiCARB | Assessing the efficacy of sodium bicarbonate in 300 older people with chronic kidney disease. | BiCARB trial information |
| MTAK | Microwave Therapy for the treatment of pre-cancerous Actinic Keratosis. | MTAK trial information |
| K-SWAY | Investigating Vitamin K supplementation to improve balance in older people – and reduce the risk of falls. | K-SWAY trial information |
| K4Kidneys | Investigating if Vitamin K therapy can improve vascular health in patients with Chronic Kidney Disease. | K4Kidneys trial information |
| PACT | Online trial examining if prescribing asthma controller medication according to genotype improves quality of life in young people with asthma. | PACT trial information |
| ALFIE | Investigating whether allopurinol can improve muscle strength and endurance in older people. | ALFIE trial information |
| ALTERED | Does allopurinol regress left ventricular hypertrophy in end stage renal disease? | ALTERED trial information |
iLFT |
A pilot evaluation of a synergistic liver diagnostic pathway: Making sense of LFTs for patients, GPs and the NHS in Scotland. Intelligent Liver Function Testing.
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| ADDUCE | Large European Union trial studying the long-term safety in ADHD treatment. | ADDUCE trial information |
| STAKT | Investigate the short term effects of an AKT inhibitor on breast cancer. | STAKT trial information |
| OPTIMISTIC | Evaluate the effect of a tailored behavioural change intervention comprising CBT and graded exercise on participation (as measured by the DM1-Activ scale) for severely fatigued patients with myotonic dystrophy type 1 compared to standard care. | OPTIMISTIC trial information |
| PREFACE | Evaluate the effect of a tailored behavioural change intervention comprising CBT and graded exercise on participation (as measured by the DM1-Activ scale) for severely fatigued patients with myotonic dystrophy type 1 compared to standard care. | PREFACE trial information |
| AMBER | Investigating whether abdominal massage can help improve the symptoms of neurogenic bowel dysfunction in people with multiple sclerosis. | AMBER trial information |
| adAPT | Investigating whether metformin, that is known to reduce insulin demand in type 2 diabetes (T2D), can do the same in children at risk of type 1 diabetes. | adAPT trial information |
| ALLAY | British Heart Foundation trial investigating whether allopurinol can regress left ventricular hypertrophy in patients with treated essential hypertension. | ALLAY trial information |
| ViaDUCT | Investigating if Vitamin D supplementation can improve Hepatitis C cure rates. | ViaDUCT trial information |
| REFORM | Research into the effects of SGLT2 inhibition on left ventricular remodelling in patients with heart failure and diabetes mellitus. | REFORM trial information |
| ALPHA | British Heart Foundation trial investigating if allopurinol can reduce right ventricular mass in lung disease associated pulmonary hypertension. | ALPHA trial information |
| HAP | What is the most effective method for providing orthodontic anchorage? A randomised clinical trial of Headgear, AbsoAnchor mini-screws, and palatal arch. | HAP trial information |
| ACES | Can an arts based creative engagement intervention following stroke improve psychosocial outcomes? | ACES trial information |
| FFIT | A gender-sensitive weight loss and healthy living programme delivered to men aged 35-65 by Scottish Premier League (SPL) football clubs. | FFIT trial information |
| PIRFECT | A podiatry intervention to reduce falls in care home residents. | PIRFECT trial information |
| SPIR-OA | The effect of spironolactone on pain in older people with osteoarthritis. | SPIR-OA trial information |
| VESUVIUS | Vascular effects of regular cigarettes versus electronic cigarette use. | VESUVIUS trial information |
| GOAL | Can eliciting and addressing health-related goals improve asthma control and asthma-related quality of life? | GOAL trial information |
| Game of Stones | A research study that texts men to help them lose weight. | Game of Stones trial information |
| SKIP-IT | Text intervention as an aid to smoking cessation in pregnant women. | SKIP-IT trial information |
| ALL ACS | Allopurinol as a possible new therapy for acute coronary syndrome. | ALL ACS trial information |
| DAPA-LVH | Does dapaglifozin regress left ventricular hypertrophy in patients with type 2 diabetes? | DAPA-LVH trial information |
| ActWELL | A randomised control trial to assess the impact of a lifestyle intervention in women invited to NHS breast screening. | ActWELL trial information |
| CUBS | Development and feasibility study to compare cue-based versus scheduled feeding for preterm infants transitioning from tube to oral feeding in neonatal units. | CUBS trial information |