Home David Horn lab David Horn lab In the Horn lab, our research focuses on antigenic variation, drug action and resistance and the application of genetic screens to the African trypanosome, Trypanosoma brucei Section menu Overview News People Projects Resources Publications Links Life Sciences On this page Chevron pointing down Gallery Thumbnail - A fluorescence microscopy image showing two Trypanosoma parasites against a black background. One parasite is stained bright green and the other is red. Both exhibit a wavy, elongated shape and contain a larger grey circular structure (the nucleus) and a smaller white dot (the kinetoplast) near one end. Text in the bottom right corner reads "Image by Lucy Glover". Gallery Thumbnail - A composite scientific diagram featuring three main elements: at the top left, the chemical structure of a molecule containing an arsenic atom (As) circled in red; on the right, a 3D ribbon diagram of a protein structure colored in a rainbow gradient, with space-filling molecular models bound within its center; and at the bottom left, a schematic showing data peaks for "Pentamidine" and "Melarsoprol" mapped onto a diagram of a sequence, with a red box labeled "AQP2" and a black box labeled "AQP3". Gallery Thumbnail - A diagram illustrating the cell cycle of a parasite. In the center, a dashed white circle with arrows indicates the phases: G1, S, G2, M, Post-M, and Cytokinesis. Arranged around this circle are six microscopy images of a red-stained parasite corresponding to each phase. The images show the progressive replication and division of the parasite's white-stained nucleus and kinetoplast until the cell begins to split into two during cytokinesis. Text in the bottom right reads "Image by Lucy Glover". Our projects Read about our projects on Human African trypanosomiasis and Animal African trypanosomiasis. Projects Latest news Read about our latest studies, achievements, and attended conferences. Read our news