Light Microscopy Facility
Light Microscopy is a widely used tool to visualise and quantify cellular behaviour and structure. The light microscopy facility offers a range of light microscope systems, each one with different capabilities so that a range techniques can be employed.
We provide dedicated support to research staff and students within who need light microscopy. We are a sister facility of LMF in Life Science and form part of the Centre for Advanced Scientific Technologies (CAST).
The LMF hosts eight advanced light microscope systems, a Zeiss LSM710 with FLIM detection and the UK’s first installation of an In Tune laser; two Leica SP5s, two DeltaVision widefield deconvolution microscopes, a Zeiss Axiovert 200M live imaging system, an inverted and upright fixed cell microscope. The facility consists of two microscope suites within the MRI with 4 systems located in the main lab block on level 5 and the remaining 4 systems on level 5 of the JWCC.
Our range of microscopy equipment provides solutions for live and fixed cell imaging and covers a range of specific techniques. Equipment in CLS can also be accessed when required. Each system has various advantages and disadvantages depending on the specific biological application and sample. The facility can therefore support a wide range of applications from Tissue Imaging by Confocal Microscopy, Protein-Protein interactions by TCSPC FLIM, high resolution imaging of cellular morphology and sub-cellular structure, multi-wavelength and multidimensional imaging of small embryos and long time lapse imaging in XY and Z with multiple fluorophores or fluorescent proteins.
Equipment and facilities
We provide information to help you select the microscope system ideal for the experiment you want to do.
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