Chronic Pain Research Group recent publications

On this page


Mills, S., Donnan, P., Buchanan, D., Smith BH,. Age and cancer type: associations with increased odds of receiving a late diagnosis in people with advanced cancer. BMC Cancer 23, 1174 (2023).

Callum Leese, Robert H Mann, Emma J Cockcroft and Kirstin Abraham. GP specialty trainees’ knowledge and values towards physical activity: a national survey of Scottish trainees. BJGP Open 9 January 2024; BJGPO.2023.0051. DOI:

Van Rysewyk A, Blomkvist R, Creighton R, Hodson F, Roomes D, Shea E, Smith BH, Toye F.  Understanding the lived experience of chronic pain: a systematic review and synthesis of qualitative evidence syntheses.  British Journal of Pain. 2023;17(6):592-605. doi:10.1177/20494637231196426

Qi Pan, Tengda Cai, Abi Veluchamy, Harry L Hebert, Peixi Zhu, Mainul Haque, Tania Dottorini, Lesley A Colvin, Blair H Smith, Weihua Meng. A genome-wide association study identifies genetic variants associated with hip pain in the UK Biobank cohort (N=221,127). medRxiv 2023.09.20.23295811; doi:

Hebert, H., Pascal, M. M. V., Smith, B. H., Wynick, D., & Bennett, D. L. H. (2023). Big data, big consortia, and pain: UK Biobank, PAINSTORM, and DOLORisk. PAIN Reports, 8(5), Article e1086.

Senaratne D, Colvin L. Chronic pain associated with temporomandibular disorders BMJ 2023; 383 :p2877 doi:10.1136/bmj.p2877

Truini A, Aleksovska K, Anderson CC, Attal N, Baron R, Bennett D, Bouhassira D, Cruccu G, Elon E, Enax-Krumova E, Davis KD, Di Stefano G, Finnerup N, Garcia- Larrea L, Hanafi I, Haroutounian S, Karlsson P, Rakusa M, Rice, AS. Sachau J, Smith BH, Sommer CT, Tolle T, Valls-Solé J, Veluchamy, A.  Joint EAN-EFIC-NeuPSIG guidelines on neuropathic pain assessment.  European Journal of Neurology (in press).

Leese, C, Abraham, K, Smith, BH. Narrative review – Barriers and facilitators to promotion of physical activity in primary care. Lifestyle Medicine. 2023; 4:e81.

Nicolson K, Senaratne D, Mills SEE, Colvin LA, Smith BH. What is the association between childhood adversity and subsequent chronic pain in adult life?  A systematic review.  British Journal of Anaesthesia Open, Volume 6, June 2023, 100139.

Attal, N, Bouhassira D, Colvin L. Advances and challenges in neuropathic pain: a narrative review and future directions, Brit J Anaesth 2023 July. 131 (1) 79-92.

Schmid, Annina B.a,*; Tampin, Brigitteb,c,d; Baron, Ralfe; Finnerup, Nanna B.f,g; Hansson, Perh,i; Hietaharju, Akij,k; Konstantinou, Kikal,m; Lin, Chung-Wei Christinen,o; Markman, Johnp; Price, Christineq; Smith, Blair H.r; Slater, Helenc,s. Recommendations for terminology and the identification of neuropathic pain in people with spine-related leg pain. Outcomes from the NeuPSIG working group. PAIN 164(8):p 1693-1704, August 2023. | DOI: 10.1097/j.pain.0000000000002919

Antoniou G, Lambourg E, Steele JD, Colvin LA. The effect of adverse childhood experiences on chronic pain and major depression in adulthood: a systematic review and meta-analysis. Br J Anaesth. 2023 Jun;130(6):729-746.

Hébert H, Veluchamy A, Bazkozos G, Fardo F, Van Ryckeghem D, Pearson ER, Colvin LA, Crombez G, Bennett DLH, Meng W, Palmer CAN, Smith BH.  Development and external validation of multivariable risk models to predict incident and resolved neuropathic pain: a DOLORisk Dundee study. Journal of Neurology 2023  270, 1076 – 1094. Pre-print available on Research Square at

Veluchamy A, Smith BH, Bennett DLB.  “The Genomics of Diabetic Neuropathy”, in Tesfaye S, Veves A, Gibbons CH, Malik RA (eds) Diabetic Neuropathy: Clinical Management (3rd edition). Totowa, New Jersey: Humana Press, in press.

Baskozos G, Hébert H, Pascal MMV, Themistocleous AC, Macfarlane GJ, Wynick D, Bennett DLH, Smith BH.  The epidemiology of neuropathic pain: an analysis of prevalence and associated factors in UK Biobank.  Pain Reports 20238(2):p e1066.   DOI: 10.1097/PR9.0000000000001066. Preprint available at 

Higgins C, Sharma S, Bimali I, Hales TG, Cameron PA, Smith BH, Colvin LA. Cross-sectional study examining the epidemiology of chronic pain in Nepal.  Pain Reports 2023 e1067. Doi 10.1097/PR9.0000000000001067

Rahmioglu N, et al (135 authors, Smith BH, 84th), Zondervan K.  The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions.  Nature Genetics 2023 55 423 – 436 Doi 10.1038/s41588-023-01323-z

Mills SEE, Brown-Kerr A, Donnan PT, Buchanan D, Smith BH. Free-text analysis of general practice out-of-hours (GPOOH) use by people with advanced cancer: an analysis of coded and uncoded free-text data.  British Journal of General Practice 2023 73: e124-e132. DOI: 

Meng, W., Reel, P.S., Nangia, C. Colvin L, Palmer C, McIntosh A, Smith BH et al. A Meta-Analysis of the Genome-Wide Association Studies on Two Genetically Correlated Phenotypes Suggests Four New Risk Loci for Headaches. Phenomics 3, 64–76 (2023).

Marta Seretny, Liana Romaniuk, Heather Whalley, Kim Sladdin, Stephen Lawrie, Catherine Elizabeth Warnaby, Neil Roberts, Lesley Colvin, Irene Tracey, Marie Fallon. Neuroimaging reveals a potential brain-based pre-existing mechanism that confers vulnerability to development of chronic painful chemotherapy-induced peripheral neuropathy, British Journal of Anaesthesia, Volume 130, Issue 1, 2023, Pages 83-93,

Hunt W, Nath M, Bowrey S, Colvin L et al. Effect of a continuous perineural levobupivacaine infusion on pain after major lower limb amputation: a randomised double-blind placebo-controlled trial. BMJ Open 2023;13:e060349. doi: 10.1136/bmjopen-2021-060349



Higgins C, Smith BH, Matthews K.  Opioid dependence disorder and comorbid chronic pain: comparison of groups based on patient-attributed direction of the causal relationship between the two conditions. British Journal of Pain 2022 16:  149 – 160. Doi: 

Mills SEE, Buchanan D, Donnan PT, Smith BH.  Death from cancer: frequent unscheduled care.  BMJ Supportive and Palliative Care 2022. Doi

Forget P, Pattullo C, Hill D, Ambekar A, Baldacchino A, Cata JP, Chetty S, Cox FJ, de Boer HD, Dinwoodie K, Dom G, Eccleston C, Fullen B, Jutila L, Knaggs RD, Lavand’homme P, Levy N, LoboDN, Pogatzki-Zahn E, Scherbaum. N, Smith BH, van Griensven J, Gilbert S.   System-level policies on appropriate opioid use. A multi-stakeholder consensus.  BMC Health Services Research 2022 22 329.  Doi  

Laskawska M, Hebert HL, Richardson C, Berlouis K, Cameron P, Colvin LA, Smith BH.  The Core Minimum Dataset for measuring pain outcomes in services in Scotland. Developing and testing a brief multi-dimensional questionnaire.  British Journal of Pain 2022  16 504 – 517. Doi 

Hay G, Korwisi B, Rief W, Treede R-D, Smith BH, Barke APain severity ratings in the 11th revision of the International Classification of Diseases: a versatile tool for rapid assessment.  Pain 2022 163 2421 – 2429.  Doi 

Ghose R, Cowden F, Veluchamy A, Smith BH, Colvin LA. Characteristics of non-fatal overdoses and associated risk factors in patients attending a specialist community-based substance misuse service.  British Journal of Pain 2022 16 458 – 466.  Doi 

Hébert H, Morales, Torrance N, Smith BH, Colvin LA.  Assessing the impact of a national clinical guideline for the management of chronic pain on opioid prescribing rates: A controlled interrupted time series analysis.  Implementation Science 2022 17 

Hébert H, Colvin LA, Smith BH.  The impact of gabapentinoid and opioid prescribing practices on drug deaths: An epidemiological perspective.  Pain Management 2022 12, Issue 4, 397 – 400.

Mills SEE, Smith BH.  “Managing Chronic Pain in Primary Care”, in Lynch ME, Craig KD, Peng PP (eds): Clinical Pain Management: a Practical Guide, 2nd edition. New Jersey, USA: John Wiley & Sons, 2022, pp138 – 146. 

Hay G, Korwisi B, Rief W, Treede R-D, Smith BH, Barke APain severity ratings in the 11th revision of the International Classification of Diseases: a versatile tool for rapid assessment.  Pain 2022 163 2421 – 2429.  Doi 

Peter Foley, Colvin LA et al Coupling cognitive and brainstem dysfunction in multiple sclerosis-related chronic neuropathic limb pain, Brain Communications, Volume 4, Issue 3, 2022, fcac124,

Ghose R, Cowden F, Veluchamy A, Smith BHColvin LA.  Characteristics of non-fatal overdoses and associated risk factors in patients attending a specialist community-based substance misuse service.  British Journal of Pain 2022 16 458 – 466.  Doi 

Baskozos G, Themistocleous A, Hebert HL, Pascal M, John J, Callaghan B, Laycock H, Crombez G, Rice ASC, Smith BH, Bennett DLH.  Classification of painful or painless diabetic peripheral neuropathy and identification of the most powerful predictors using machine learning models in large cross-sectional cohorts.   BMC Medical Informatics and Decision Making 2022 22 144. Doi 

Mills SEE, Donnan PT, Buchanan D, Smith BH.  Community prescribing trends and prevalence in the last year of life, for people who die from cancer.  BMC Palliative Care 2022 21 120.  Doi 10.1186/s12904-022-00996-3  . Available at 

Parker RA, Sande TA, Laird B, Colvin LA et al. Bayesian methods in palliative care research: cancer-induced bone pain. BMJ Supportive & Palliative Care 2022;12:e5-e9.