Dr Laura Cleghorn

Reader

Drug Discovery Unit, School of Life Sciences

Biological Chemistry and Drug Discovery, School of Life Sciences

Laura Cleghorn

Contact

Biography

Laura obtained a BSc(Hons) in Chemistry from the University of Edinburgh then worked at Organon Laboratories as a graduate medicinal chemist before moving to the University of Leeds where she obtained a PhD in Organic Chemistry in the lab of Prof. Ron Grigg. In 2006, Laura joined the newly formed Drug Discovery Unit as a medicinal chemist, initially working on Human African Trypanosomiasis, before moving to the Tuberculosis group in 2013, where she became the Portfolio Leader in 2020, and was afterwords promoted to the position of Reader in 2022.

Research

Laura is the Tuberculosis Portfolio Leader in the Dundee Drug Discovery Unit (DDU) where she leads a team of multi-disciplinary researchers focussed on identifying novel inhibitors with the potential to be progressed toward pre-clinical candidate selection and evaluated as a new therapy for TB.

The research in Laura’s group spans the drug discovery pipeline from identifying and progressing novel screening hits through to late-stage optimisation towards pre-clinical leads and ultimately new therapeutics. Multiple strategies are employed to achieve the goal of identifying molecules targeting new pathways or those exhibiting improved profiles against a known mechanism of action. This is a highly collaborative research program where the work is coordinated with an international network of collaborators to maximise impact.

View full research profile and publications

Stories

Press release

A University of Dundee researcher heading up a multi-million dollar effort to find new treatments for tuberculosis, malaria, and future viral pandemic diseases has warned that the Covid-19 pandemic may lead to a rise in TB infections globally.

Published on 23 March 2022