Post-Doctoral Researcher - UOD2267

We are recruiting a Postdoctoral Researcher to join the of Professor Adrian Saurin in the Department of Genome Integrity at The University of Dundee. This is a fixed-term appointment for 36 months in the first instance, with possible extension thereafter.

We are looking for a talented ambitious postdoctoral researcher to join a Cancer Research UK-funded programme to examine the role of cell enlargement and senescence in cancer progression and treatment. This builds on our recent work demonstrating a role for cell enlargement in driving senescence (1-2) and genome instability (3) following anti-cancer therapy.

1) Foy et al, Molecular Cell, 2023

2) Crozier et al, Molecular Cell, 2023

3) Pareri et al, bioRxiv, 2025.

For further information about this position please contact Prof Adrian Saurin at [email protected].

To find out more about the lab and the project in general please visit www.saurinlab.com. In particular, check out the philosophy section to learn more about lab culture.

Your priorities will include:

• Using various 'omics approaches to examine how cell enlargement drives senescence following cancer therapy
• Using a wide range of cell biology methods, including live-cell microscopy, to characterise the transition into senescence
• Studying how cell enlargement drives genome instability following senescence evasion or escape.
• Performing CRISPR screens to identify targetable vulnerabilities in enlarged mammalian cell types.

Who we are looking for:

• A highly-motivated and ambitious postdoctoral researcher with a passion for science
• A candidate with a PhD in relevant scientific area, with at least one main author publication.
• A candidate with a strong scientific background in cell biology and experience of working in the senescence field.

Please note, applications may close earlier than advertised if a suitable candidate is identified.