The Ninewells Cancer Campaign (NCC) - Fraser Fellowships Doctoral Training Programme (DTP) in Precision Cancer Medicine is an exciting new DTP that will expand interdisciplinary cancer research in the School of Medicine at the University of Dundee, focussing on translational research in precision cancer medicine.
This DTP offers opportunities for up to 7 students to join our cancer research community as part of a flagship programme in the School of Medicine. Based at Ninewells Hospital and Medical School Campus, students will be embedded in vibrant multidisciplinary research teams with a mix of cancer clinicians and scientists. Excellent research training opportunities are provided, including DTP specific training events, and more general training and educational activities in the school and university available as part of our Doctoral Academy.
Precision medicine is a central research theme in the School including in cancer with activity across a number of tumour types, particularly oesophageal, gastric, skin, colon, brain and breast.
Current research involves a broad range of clinical and scientific academic disciplines including:
- applied mathematics
- medical oncology
- molecular and cell biology
- computer science
- genomics and informatics
Our interdisciplinary cancer research expertise comprises clinical trials, experimental medicine, and laboratory based research.
The DTP provides research funding, stipend or salary, university fees and a travel allowance for 3-4 years, and is open to scientifically qualified applicants and also clinicians who wish to undertake research training.
Projects are interdisciplinary translational cancer research focussed on the clinical application of precision medicine and all involve joint supervision between clinical and non-clinical co supervisors. DTP Projects are listed below:
Tackling drug resistance – a role for precision medicine in ovarian cancer
Supervisors:Dr Gillian Smith, Dr Michelle Ferguson
Nrf2 in the microenvironment of glioma
Supervisors:Professor Albena T. Dinkova-Kostova, Dr Hannah Lord
Targeted anti-cancer therapy with CDK4/6 inhibitors
Supervisors:Dr Adrian Saurin, Professor Russell Petty
Development of a liquid biopsy assay to assist in identifying patients at high risk of colorectal neoplasia in symptomatic patients with elevated faecal haemoglobin concentrations
Supervisors:Dr Craig Mowat, Dr David Baty
ADOPT 2: Precision drug dosing for cancer patients using simple, home-based pharmacokinetic profiling
Supervisors:Professor Charlotte Proby, Professor Roland Wolf
Dissecting the potential for GSK3 inhibition to improve lymphoma treatment
Supervisors:Professor Calum Sutherland, Dr Sudhir Tauro
Prediction of individual patient survival and GBM tumour characteristics
Supervisors: Professor Douglas Steele, Dr Kismet Ibrahim,Dr Dumitru Trucu
Exploiting the full potential of BACH1 as an anti-metastatic target in lung cancer
Supervisors:Dr Laureano de la Vega, Professor Russell Petty
Identifying ion channels as potential targets in personalised colon cancer therapy and biomarkers of prognosis
Supervisors:Professor Tim Hales, Dr Mairi McLean
Non-clinical studentships are funded 4 years and clinical for 3 years full time.
- tuition fees, including overseas student fees if required
- all research consumables stipend at RCUK rates or clinical research fellow salary as appropriate
- and an allowance for congress travel
Must possess or be expected to possess by the time of starting the PhD, at least one of the following:
- First class, or upper second class honours degree in a relevant scientific discipline, or equivalent
- Postgraduate Masters degree in a relevant scientific discipline, or equivalent
- Primary medical Qualification MB ChB or equivalent
English language requirements
- IELTS minimum overall score of 6.5 (Reading 5.5, Listening 5.5, Speaking 5.5 Writing 6.0)
How to apply
Applications should be made to the DTP, and NOT to individual projects. Applications made direct to individual projects or supervisors will not be accepted.
Applicants should complete the application form for the doctoral training programme and list up to 3 projects that they are interested in, in order of preference.
Candidates should provide a 500 word statement supporting their application which should include detail of:
- Their personal motivation to undertake an interdisciplinary PhD in precision cancer medicine.
- Why this DTP in general is of interest to them.
- Why their selected projects in particular are of interest to them.
Candidates are strongly encouraged to contact potential supervisors of the projects of interest listed in their application.
A curriculum vitae detailing candidates educational qualifications and other relevant information including the details of 2 academic referees should be submitted together with the application form.
The closing date for applications is Monday 22 March 2021.
Candidates will be selected for interview which are expected to take place remotely at the end of March 2021.
Allocation to projects will be on the basis of application and interview ranking, with a matching process in which the highest ranked students are offered their first choice project, and so on.
If you have further questions, please email NinewellsCC@dundee.ac.uk and a member of the team will help with your enquiry.