17 Jun 2015

Discovery of a novel antimalarial compound published in Nature

The details of the discovery, properties and mechanism of action of a novel antimalarial compound, DDD107498, have been published in the journal Nature. DDD107498 has the potential to treat malaria patients in a single dose, including those with malaria parasites resistant to current medications, and help reduce the transmission of the parasite. The compound was identified through a collaboration between the University of Dundee’s Drug Discovery Unit (DDU) and Medicines for Malaria Venture (MMV). “The publication describes the discovery and profiling of this exciting new compound,” said P...

15 Jun 2015

A super-targeted method of destroying tumour proteins

Scientists at the University of Dundee have developed a super-targeted method of destroying malevolent proteins in tumour cells, removing the threat of collateral damage to surrounding proteins. The research team led by Dr Alessio Ciulli in the College of Life Sciences at Dundee has developed a small molecule that can hone in highly selectively on a single protein, BRD4, which has emerged as an attractive drug target for cancer. BRD4 and its sister proteins BRD2 and BRD3 are members of a group of proteins known as the BET bromodomains. These have previously been identified as being strong targets for drug ...

9 Jun 2015

Eye imaging software could aid disease diagnosis, study suggests

Imaging technology that scans blood vessels in the eye could be used to help diagnose a wide range of diseases, according to a study carried out by the Universities of Edinburgh and Dundee. Researchers say software designed to assess the health of vessels in the retina could help scientists spot the early signs of heart disease, diabetes and dementia. Changes to the retina are often a sign of sickness elsewhere in the body. The software – known as VAMPIRE – allows scientists to analyse the shape of blood vessels in thousands of images at a time and can identify known indicators of disease. VAMP...

Eye imaging software could aid disease diagnosis, study suggests

5 Jun 2015

Mine-crafting the future of Dundee’s waterfront

Dundee’s central waterfront is the midst of a £1billion transformation. The project has already proved attractive to the world’s leading architects, including Kengo Kuma, designer of the V&A Museum of Design, Dundee. Now the city’s schoolchildren will show how it would look if they were set free to design the waterfront, using the gaming phenomenon Minecraft. Primary 6 and 7 pupils around the city have been working for the past few months on a project led by the University of Dundee and Dundee City Council. Simultaneously, pupils from nine secondary schools across the city have ...

3 Jun 2015

Dundee shares in new arts research funding

Three University of Dundee projects, looking at whaling, rural planning  and 18th century reading habits, will share in a new £380,000 round of arts research funding. The funding comes from Applied Research Collaboration Studentships (ARCS), supported by the Scottish Funding Council and universities themselves. Seven projects across Scotland have been granted £54,000 each under the ARCS initiative. The funding covers two joint projects with the University of Stirling. The first will examine library records dating back to 1747 to gauge how reading habits and book borrowing could affect peop...

Dundee shares in new arts research funding