11 Aug 2015

Research offers clues to Parkinson’s disease causes and potential drug target

A stage-by-stage picture of a key cellular mechanism associated with the development of Parkinson’s Disease has been captured for the first time by a research team led by the University of Dundee.  The findings give further understanding of the possible causes of Parkinson’s disease and offer potential for multiple targets for therapeutics to be developed.  Parkinson’s disease (PD) is a neurodegenerative disorder with severe motor and non-motor symptoms. There are several genes associated with PD, with autosomal recessive juvenile Parkinsonism (ARJP) being the most prevalent inh...

Research offers clues to Parkinson’s disease causes and potential drug target

10 Aug 2015

Unravelling the genetics of diabetic neuropathic pain

Research from the University of Dundee could one day help identify which diabetic patients are most likely to experience neuropathic pain and how best to treat them by studying their genetic make-up. Neuropathic pain, caused by a lesion or a disease affecting the nervous system, is one of the most common complications of diabetes, currently affecting around 1 in 4 diabetic patients in the UK. The condition presents itself differently from patient to patient, ranging from constant burning pain to intermittent sharp, shooting pains, but is chronic and debilitating and greatly impairs the quality of life of t...

Unravelling the genetics of diabetic neuropathic pain

20 Jul 2015

Immune system ‘on switch’ breakthrough could lead to new targeted drugs

A crucial ‘on switch’ that boosts the body’s defences against infections has been successfully identified in new scientific research. The breakthrough made by researchers at the University of Aberdeen and the University of Dundee could lead to the development of new drugs to enhance the body’s immune responses to attack, which could benefit people suffering from cancer and other serious conditions. Their findings have been published in the Journal of Molecular and Cell Biology http://www.ncbi.nlm.nih.gov/pubmed/26063615. “We have shown that the cells which turn on our immune r...

20 Jul 2015

Professor Irwin McLean awarded Buchanan Medal by Royal Society

Professor Irwin McLean of the University of Dundee has been awarded the prestigious Buchanan Medal of the Royal Society. The Buchanan Medal is awarded by the Royal Society, the world’s oldest scientific academy in continuous existence, for distinguished contributions to the medical sciences. Irwin McLean is Professor of Human Genetics and Scientific Director of the Centre for Dermatology and Genetic Medicine at Dundee. He is a world renowned expert in the genetics of skin diseases, and his research group has identified the causative genes for more than 20 human diseases. Professor McLean said, &ldquo...

14 Jul 2015

Research project to lay foundations for offshore wind farms

The University of Dundee is to lead a major research project to determine whether cheaper, more environmentally friendly, and more effective foundations can be developed for the offshore renewables industry. The project, funded by a £1million grant from the Engineering and Physical Sciences Research Council, will look at the use of screw piles for offshore installations. These are foundations which are screwed into the ground and are widely used onshore, one example being to support motorway signs and gantries. “The UK has challenging targets for expansion of energy from renewables with the pot...