26 Sep 2016

Research reveals genetic mutations driving skin cancer

A research collaboration led by the University of Dundee and the Cancer Research UK Beatson Institute has uncovered a common underlying cause in many cases of one of the most widespread forms of skin cancer. The rate of cutaneous squamous cell carcinoma (cSCC), a potentially devastating form of the disease, is rapidly rising and has more than doubled in Scotland over the last 20 years. Despite this growing problem, there is relatively little concrete understanding as to what drives these cancers to form. In order to gain a fuller picture of the processes driving cSCC, the multidisciplinary research team ex...

Research reveals genetic mutations driving skin cancer

21 Sep 2016

Stimulating neurons could protect against brain damage

A breakthrough in understanding how brain damage spreads – and how it could potentially be limited – has been made through a collaboration between neuroscientists and engineers at the Universities of Dundee and Strathclyde. They have uncovered a previously unknown mechanism in the brain that allows networks of neurons to protect against the kind of spreading secondary damage seen in cases of strokes and traumatic brain injuries. “If this network activity could be triggered clinically as soon as possible then major brain damage could be minimised and recovery periods shortened,” said...

Stimulating neurons could protect against brain damage

20 Sep 2016

Academia-industry collaboration gets £7 million to accelerate drug discovery

The University of Dundee has announced renewed funding of more than £7million from three of the world’s leading pharmaceutical companies to support its Division of Signal Transduction Therapy (DSTT). Pharmaceutical giants Boehringer Ingelheim, GlaxoSmithKline and Merck will provide support of £7.2 million until 2020, enabling scientists at Dundee to continue their fundamental research in multiple therapeutic areas, including cancer, arthritis, lupus, hypertension and Parkinson’s disease. This new round of funding secures 38 posts at Dundee for the next four years. The DSTT comprises...

Academia-industry collaboration gets £7 million to accelerate drug discovery

19 Sep 2016

‘Molecular origami’ enables scientists recreate RNA process in lab

University of Dundee scientists have used nanotechnology to perform ‘molecular origami’ in order to replicate naturally occurring genetic processes, research that may one day help enable the precise, targeted delivery of drug molecules in humans. Nanotechnology is engineering at an unimaginably small scale, that of individual molecules. Nature has led the way with this, constructing complex structures and functioning machines inside living cells, and scientists are taking a lead from this to engineer molecular-scale objects using natural molecules as building blocks. Professor David Lilley,&nbs...

‘Molecular origami’ enables scientists recreate RNA process in lab

14 Sep 2016

Dundee researchers contribute to `open science’ project for malaria drugs

Malaria remains one of the world’s leading causes of mortality in developing countries. Last year alone, it killed more than 400,000 people, mostly young children. This week in ACS Central Science, an international consortium of researchers, including scientists at the University of Dundee, unveils the mechanics and findings of a unique “open science” project for malaria drug discovery that has been five years in the making. The current gold standard antimalarial treatments are based on artemisinin, a compound developed in the 1970s in China, combined with a partner drug. Yet, resistance ...

Dundee researchers contribute to `open science’ project for malaria drugs