16 Nov 2016

Male fertility research boosted by Gates Foundation grant

The University of Dundee announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation. The project will enable a unique collaboration bringing together expertise at Dundee in male fertility and drug discovery to help identify possible new male contraceptive drugs. Grand Challenges Explorations (GCE) supports innovative thinkers worldwide to explore ideas that can break the mould in how we solve persistent global health and development challenges. The Dundee project, led by Professor Andrew Hopkins (Chair of Medicinal Informatics), Dr Pau...

Male fertility research boosted by Gates Foundation grant

9 Nov 2016

Award for ‘outstanding’ research

Scientists from the University of Dundee have written one of the five most outstanding research papers of the past year, according to a prestigious academic journal. An international study led by Professor Chim Lang and Dr Graham Rena at Dundee’s Division of Molecular and Clinical Medicine showed how Metformin, the world’s most commonly used Type 2 diabetes drug, may be ‘repurposed’ to treat non-diabetic conditions. The paper was published in Circulation Research in August and has been named in the journal’s Best Manuscript Awards 2016 alongside four other scientific papers fr...

Award for ‘outstanding’ research

4 Nov 2016

`Molecular commando’ identified to tackle hypoxia pathway

Scientists at the University of Dundee have identified a `molecular commando’ which can be stealthily deployed to activate a hypoxic response, a process which can help to fight a range of conditions including stroke, angina, colitis and brain injuries. A Dundee team led by Professor Alessio Ciulli in the School of Life Sciences have used pioneering techniques to develop a `small molecule’ chemical probe called VH298, which offers highly targeted access to the parts of the cell which regulate hypoxia, known as the hypoxic signalling pathway. “Using a small molecule like this offers a highl...

`Molecular commando’ identified to tackle hypoxia pathway

4 Nov 2016

New protein key to better drugs for neglected diseases

A newly identified method of activating drugs to combat one of the world’s most destructive `neglected’ diseases could lead to better medicines according to new research led by the University of Dundee. Visceral leishmaniasis (VL) is a disease which blights the developing world with 200,000 to 400,000 new cases and an estimated 40,000 deaths annually, making it the second biggest parasitic killer after malaria. The vast majority of cases are seen in seven countries - India, Nepal, Bangladesh, Brazil, Ethiopia, South Sudan and Sudan. There are no vaccines available and current drug treatments al...

New protein key to better drugs for neglected diseases

2 Nov 2016

Efforts to help doctors treat the dying recognised

A plaque marking the University of Dundee’s efforts to help doctors care more effectively for the dying has been unveiled at Ninewells Hospital. Palliation and the Caring Hospital (PATCH), a charity which supports specialist palliative care for patients in Scotland, unveiled the plaque at a ceremony attended by representatives of the University’s School of Medicine and NHS Tayside. The charity initiated the accolade in recognition of the unique collaboration between the three organisations, who have developed a series of workshops to help healthcare professionals have honest and open conversati...

Efforts to help doctors treat the dying recognised