MEMO and HRC have various clinical trials and studies, including collaborative projects with UK centres and other Scottish Universities.
Allopurinol is a medication usually used to prevent gout. Allopurinol has several positive effects on the heart and blood vessels, is inexpensive and is already widely used in patients. Ischaemic heart disease is common in people in the UK. In this study, we want to improve the treatment of patients with ischaemic heart disease. We want to investigate whether adding allopurinol to these patients’ usual medications will reduce their risk of having a stroke, heart attack or of dying due to cardiovascular disease.
Standard Care versus Celecoxib Outcome Trial (SCOT)
The SCOT study is designed to find out if celecoxib is definitely better, worse or just the same as the other available NSAIDs. Because SCOT will eventually involve many thousands of participants we will also be able to look at the relative safety of all the NSAIDs in common use. This information will be of great value to everyone who needs to take these drugs on a regular basis. It will allow doctors to make the best choice for people with arthritis, not just for their joint pains but also for their general health.
The FAST study is designed to find out if Febuxostat is definitely better, worse or just the same as Allopurinol.
This information will be of great value to everyone who needs to take these drugs on a regular basis.It will allow doctors to make the best choice for people with arthritis, not just for gout pains but also for their general health.
Time Study - Antihypertensive Study
In recent years, special monitors that can measure blood pressure throughout the day and the night have been developed. Results from studies using these monitors have suggested that night time blood pressure might be a better measurement of the benefits of blood pressure lowering. In addition, tablets taken at night lower night-time blood pressure more than tablets taken in the morning. The big question is, would night time dosing be better (or worse) than morning dosing in preventing the bad things associated with high blood pressure (such as strokes and heart attacks)?
MEMO Safety Project
The MEMO Safety Project wants to engage patients in medicine safety and effectiveness.
By collecting participants medical history it is hoped the data will shine a light on what medicines are most effective and what medicines have side effects.
Prevention And Treatment of Hypertension With Algorithm-based therapY (PATHWAY)
HRC is one of 8 UK centres taking part in the PATHWAY studies. PATHWAY comprises three clinical trials of licensed medicines, which aim to address some important areas of uncertainty in the current management of hypertension:
1. Monotherapy vs. dual therapy for initial treatment for hypertension
2. Optimal treatment of drug resistant hypertension
3. Comparison of single and combination diuretics in low-renin hypertension
Swine Flu Trial
The swine flu trial was undertaken by Dundee University to monitor the H1N1 influenza vaccine.
The trial has ended but the results have been published in the British Journal of Clinical Pharmacology.