Valerie Godfrey

+44 (0)1382 383113
TASC Quality Assurance Manager

Biography

Valerie graduated from the University of Dundee with a BSc (Hons) in Medical Microbiology. She first started work in the NHS Bacteriology labs at Ninewells Hospital where she gained her Fellowship with the Institute of Biomedical Science. She took 2 years out during this time and completed a MSc by research thesis (potato bacterial diseases) at the Scottish Crop Research Institute (now James Hutton Institute). She moved to the University of Dundee Clinical Pharmacology Department in 1999. She worked in the lab analysing samples from clinical research studies and also managed her own research projects. Valerie received her PhD (steroid hormones and inflammatory processes) in 2005 under the supervision of Professor Allan Struthers and Dr Geoff Lyles. She continued as a Scientific Officer in the Clinical Pharmacology Dept until 2009 when she was appointed as Clinical Research Manager for the Division of Medical Sciences. From here, she moved into the area of Quality Assurance in laboratories and subsequently expanded to become Quality Assurance Manager for Tayside Medical Science Centre (TASC) covering all aspects of clinical research/trials to ensure Good Clinical Practice and regulatory (MHRA) compliance.

As TASC QA Manager, Valerie has been responsible for leading the development, coordination, maintenance and review of a Quality Management System that encompasses the life of clinical research studies from start to finish.

Research

Lectures and conferences

November 2014 - NHS Research Scotland (NRS) Conference, Edinburgh

September 2015 – MHRA GLP and GCP Laboratories Symposium, Birmingham

October 2015 – NRS Conference, Glasgow

February 2016 – School of Medicine Research Symposium, Crieff

October 2016 – NRS Annual Conference, Delivering Research Excellence, Glasgow

November 2016 – School of Medicine Research Symposium, Dundee

Impact

Member of Research Quality Association (2010-present)

Founder member and current chair of National Academic Research Quality Assurance Group (2014-present)

Publications

1. Pauriah, M., Khan, F. et al. B-type natriuretic peptide is an independent predictor of endothelial function in man. Clinical Science. 2012. 123:307-312.

2. Godfrey, V., Martin, A.L., et al. Effects of aldosterone and related steroids on LPS-induced increased expression of inducible NOS in rat aortic smooth muscle cells. British Journal of Pharmacology. 2011. 164:2003-2014.

3. Kennedy, L., Pauriah, M., Godfrey, V. et al. Global array-based transcriptomics from minimal input RNA utilising an optimal RNA isolation process combined with SPIA cDNA probes. PLoS ONE. 2011. 6(3):1-17.

4. AlZadjali, M.A., Godfrey V. et al. Insulin resistance is highly prevalent and is associated with reduced exercise tolerance in nondiabetic patients with heart failure. Journal of the American College of Cardiology. 2009. 53(9): 747-753.

5. Uma, R., Forsyth, J.F. et al. Polymorphisms of the angiotensin converting enzyme gene in relation to intrauterine growth restriction. Acta Obstetricia et Gynecologica. 2010. 89:1197-1201.

6. Uma, R., Forsyth, J.F. et al.Polymorphisms of the angiorensin converting enzyme gene in early-onset and late-onset pre-eclampsia. Journal of Maternal Fetal Neonatal Medicine. 2010. 23(8):874-879.

7. Uma, R., Godfrey, V. et al. Correlation of angiotensin converting enzyme activity and the genotypes of the I/D polymorphism in the ACE gene with preterm birth and birth weight. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2008. 141:27-30.

8. Godfrey, V. et al. Effect of spironolactone on C-reactive protein levels in patients with heart disease. International Journal of Cardiology, 2007. 117(2):282-284.

9. Godfrey, V. et al. The functional consequence of the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene in young healthy volunteers. Cardiovascular Drug Reviews, 2007. 25(3):280-288.

10. Lang, C.C., Godfrey, V. et al. The functional consequence of the GLU298ASP polymorphism of the eNOS gene in humans. Clinical Pharmacology & Therapeutics, 2006. 79(2):P65.

11. Lang, C.C., Godfrey, V. et al. Prevalence of insulin resistance among non-diabetic chronic heart failure patients and its relation to disease severity. Circulation. 2007. 116 (II):705-706.

12. Carmichael, I.C., V. Godfrey & G. Nicholson. Errors associated with determining the susceptibilities of staphylococci to trimethoprim by the Vitek GPS-AK card. Journal of Antimicrobial Chemotherapy, 1999. 44(2):293-294.

13. Godfrey, V. et al. Problems in identifying blood culture isolates. British Journal of Biomedical Science, 1998. 55(1):12-13.