Shona Matthew

+44 (0)1382 383396
NIHR Global Health Research Unit Manager

Other

Shona has welcomed studentship applications from undergraduate and Masters students interested in Medicine and Physics. Since coming to Dundee in 2012, she has supervised a number of students from the University of St Andrews (during their final year projects of during their summer vacations) and from the University of Dundee (Masters and DCAT). She has also supervised students from other national and international Universities. Name: Eilidh Avison Year: 2017 Home University: University of Durham Subject: Physics Year of Study: 5th Achievements: Accepted on the Scottish Training Scheme for Medical Physics Name: Catriona Rooney Year: 2017 Home University: University of St Andrews Subject: Physics Year of Study: 3rd Year Project Title: First pass perfusion bolus timings as an additional diagnostic tool in cardiovascular MRI Achievements: Accepted as a PhD Candidate, Oxford University 2018 Name: Owain Lloyd Thomas Year: 2017 Home University: University of Dundee Subject: Medicine Year of Study: 1st Year Project Title: Texture analysis as an addition tool to ASPECT score Achievements: Poster submission to SHARP 2017 Name: Brianna Burton Year: 2016-2017 Home University: University of St Andrews Subject: Maths & Physics Year of Study: 4th Year Project Project Title: Hyper Signals in Non-Contrast Images of the Brain Achievements: Poster: DHT 2016, SINAPSE 2017 Accepted for Biomedical Engineering MSc – Awarded Bursary Name: Awad Alzahrani Year: 2017 Home University: University of Dundee Subject: Medical Imaging Year of Study: Masters Project Title: Comparison of Different Post-Processing Methods for MR Angiography (CT) Achievements: Poster submission to SHARP 2017 Awarded PhD Position with UoD Name: Ping Tie Year: 2017 Home University: University of Dundee Subject: Medical Imaging Year of Study: Masters Project Title: Comparison of Different Post-Processing Methods for MR Angiography (MRI) Achievements: Awarded MRS PhD Position with UoD Name: Chun Ooi Year: 2016 Home University: University of Dundee Subject: Medicine Year of Study: 3rd Project Title: Developing an electronic data system (Guerbet project) Achievements: Poster presentation SHARP 2016 Name: Brianna Burton Year: 2016 Home University: St Andrews Subject: Maths & Physics Year of Study: 3rd Year Project Title: Blood Mimic Theil Embalmed Cadavers Poster Presentation SINAPSE 2017 Poster Presentation Dr Hadwin 2017 Name: Rachel Stewart Year: 2016 Home University: St Andrews Subject: Physics Year of Study: 4th Project Title: Perfusion of Theil Embalmed Cadavers Achievements: Offered part-time employment with UoD Name: Aaron Daubney Year: 2016 Home University St Andrews Subject: Physics Year of Study: 4th Project Title: Neuro MRI Pre/post scanner upgrade Achievements: Winner of poster prize, SINAPSE 2016 Accepted on Teacher Training Course (Physics) Name: Catherine Brearly Year: 2016 Home University: St Andrews Subject: Physics Year of Study: 4th Project Title: Spiral/Non Spiral Flow – flow rig and cadaveric models Achievements: Poster presentation, SINAPSE 2016 Employed Nuclear Industry Name: Benjamin Mignot Year: 2015 Home University: ENSEEIHT Paris Subject: Engineering Year of Study: 2nd year Project Title: CFD modelling of AVF Achievements: International summer placement Name: Kirsty Butt Year: 2015 Home University: Dundee Subject: Medicine Year of Study: 3rd year Project Title: Developing an electronic data system (Guerbet project) Achievements: Poster presentation UKRC 2016 Name: Amy Gallacher Year: 2015 Home University: St Andrews Subject: Physics Year of Study: 4th Year Project Title: Phantom testing and quality assurance of cardiac MRI Achievements: Awarded casual contract with NHS Tayside Medical Physics Name: Laura Young Year: 2015 Home University: St Andrews Subject: Physics Year of Study: 5th Year Project Title: Computed tomography: Dose, audits, image quality and optimisation techniques Achievements: 2015 Employed by Guerbet as researcher 2015-2018 UoD PhD candidate, ReDVA Fellow 2015 & 2016: Poster presentation, school of medicine symposium. 2016: Poster presentation SHARP 2016: Oral presentation to department of radiology Name: Conor MacDonald Year: 2015 Home University: St Andrews Subject: Physics Year of Study: 5th Year Project Title: A computational validation of MRI as a surveillance tool for vascular access in end-stage renal disease Achievements: Winner of the Undergraduate Awards (Dublin) Conference paper; The Undergraduate Awards Winner of best experimental physics project, St Andrews 2015-2018 UoD PhD candidate ReDVA Fellow Name: Zi Yi Tew Year: 2014 & 2015 Home University: Dundee Subject: Medicine Year of Study: 2nd & 3rd Year Project Title: 2014: Improving blood flow parameters in vascular disease Achievements: 2014: Poster presentation at SHARP 2015: Creating an electronic data system within NHS 2015: Poster presentation UKRC Name: Alexandra Webb Year: 2014 Home University: St Andrews Subject: Physics Year of Study: 5th Year Project Title: Improving blood flow parameters in Dialysis Achievements: 2 x Poster presentations at American Society of Nephrology 2014. Employed by NHS England (vascular lab) Name: Russell Murdoch Year: 2014 Home University: St Andrews Subject: Physics Year of Study: 5th Year Project Title: Measurement of the concentration ratio of PCr to ATP using MRS Achievements: Poster presentation & oral presentation at ESMRMB Accepted on the medical physics Masters course in Australia. Name: Silvie Aikman Green Year: 2013 Home University: Dundee Subject: Medicine Year of Study: 2nd Year Project Title: Stenosis detection reproducibility – TASCFORCE cohort Name: Julia Scott Year: 2013 Home University: St Andrews Subject: Physics Year of Study: 1st Year Project Title: Overview of medical imaging Achievements: Accepted for the medical physics training scheme in 2015

Biography

Alumna of the University of St Andrews, Shona came to the University of Dundee in 2012 with a strong background in laser, particle, solid-state and medical physics. Working as part of Prof J Graeme Houston’s research group, Shona was involved in a number of cardiovascular (CVD) magnetic resonance imaging studies aimed at the accurate and early detection of Cardiovascular disease in distinct patient groups.

In 2014, Shona accepted the role of Project Manager for the ReDVA project (2013 – 2017); an EU funded, FP7 joint industry-academia research programme aimed at overcoming some of the scientific and technical barriers to the understanding, development and adoption of technologies to combat the failure of renal dialysis venous access. 

Following the successful completion of the ReDVA project, Shona moved to Professor Colin Palmer’s group to take on the role of NIHR Global Health Research Unit Manager for the INSPIRED project (2017 -2021). The aim of the project is to combine retinal imaging and molecular information to achieve personalised diabetes treatment in India. In particular to provide a low cost, agile and sustainable solution supported by telemedicine for outreach to the poorest populations. 

Much of Shona’s research has, and continues to be, in collaboration with other departments, Universities and NHS trusts, as well as with national and international partners. 

Research

Oct 2017 – present         

Global Health Research Unit Manager

University of Dundee, Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Dundee, United Kingdom.

To combine retinal imaging and molecular information to achieve personalised diabetes treatment in India. In particular to provide a low cost, agile and sustainable solution supported by telemedicine for outreach to the poorest populations.

Feb 2014 – Nov 2017       Project Manager (ReDVA)

University of Dundee, Division of Cardiovascular & Diabetes Medicine, Dundee, United Kingdom.

EU funded, FP7 joint industry-academia research programme to overcome the scientific and technical barriers to the understanding, development and adoption of technologies to combat the failure of renal dialysis venous access.

Feb 2012 – Jun 2014        Industry funded Post-Doctoral Researcher

University of Dundee, Division of Cardiovascular & Diabetes Medicine

Dundee, United Kingdom. 

Contrast Enhanced Cardiac Magnetic Resonance First-Pass Perfusion Imaging: Pre & Post Contrast Analysis Comparison.

Oct 2009 – Dec 2016        TASCFORCE

University of Dundee, Division of Cardiovascular & Diabetes Medicine

Dundee, United Kingdom. 

Cardiac Magnetic Resonance Imaging First-Pass Perfusion Imaging: Image Optimisation and Image Analysis. 

Nov 2007 – Aug 2012      PhD Student

The Department of Physics & Astronomy, University of St Andrews, St Andrews, United Kingdom. 

The Development and Assessment of Cardiac Magnetic Resonance Imaging for the Detection of Age and Disease Related Changes in the Human Heart: URL: http://hdl.handle.net/10023/3558.

Publications

Shaween Al-Talabany, Ify Mordi, J. Graeme Houston, Helen M. Colhoun, Jonathan R. Weir-McCall, Shona Z. Matthew, Helen C. Looker, Daniel Levin, Jill J. F. Belch, Fiona Dove, Faisel Khan, Chim C. Lang: Epicardial adipose tissue is related to arterial stiffness and inflammation in patients with cardiovascular disease and type 2 diabetes. BMC Cardiovascular Disorders 12/2018; 18(1)., DOI:10.1186/s12872-018-0770-z

Laura K Young MPhys 1, Dr Stephen J Gandy Ph.D2, Lukasz Priba MSc2, Dr Shona Z Matthew Ph.D1, Professor J Graeme Houston MD, FRCR1. The impact of different MRI equipment and scanning parameters on signal intensity ratio measurements in phantoms and healthy volunteers – implications for interpreting Gadolinium signal changes within the brain. (Accepted Aug 2018) Eur. Rad.

Conor MacDonald, Stephen Gandy, Eilidh Avison, Shona Matthew, Rose Ross, J. Graeme Houston. Non-Contrast MRI Methods as a Tool for the Pre-Operative Assessment and Surveillance of the Arterio-Venous Fistula for Haemodialysis. (Accepted Aug. 2018) Magnetic Resonance Materials in Physics, Biology and Medicine.

Matthew A Lambert, Jonathan R Weir-Mccall, Marco Salsano, Stephen J Gandy, Daniel Levin, Ian Cavin, Roberta Littleford, Jennifer A Macfarlane, Shona Z Matthew, Richard S Nicholas, Allan D Struthers, Frank Sullivan, Shelley A Henderson, Richard D White, Jill J F Belch, J Graeme Houston, Richard White Douglas: Prevalence and Distribution of Atherosclerosis in a Low- to Intermediate-Risk Population: Assessment with Whole-Body MR Angiography. Radiology 05/2018; 287(3)., DOI:10.1148/radiol.2018171609

Jonathan R. Weir-McCall, Matthew Lambert, Stephen J. Gandy, Jill J. F. Belch, Ian Cavin, Shelley A. Henderson, Roberta Littleford, Jennifer A. Macfarlane, Shona Z. Matthew, R. Stephen Nicholas, Allan D. Struthers, Frank Sullivan, Richard D. White, J. Graeme Houston: Systemic arteriosclerosis is associated with left ventricular remodeling but not atherosclerosis: A TASCFORCE study. Journal of Cardiovascular Magnetic Resonance 12/2017; 20(1)., DOI:10.1186/s12968-018-0428-0

Eoin A. Murphy, Rose A. Ross, Robert G. Jones, Stephen J. Gandy, Nicolas Aristokleous, Marco Salsano, Jonathan R. Weir-McCall, Shona Matthew, John Graeme Houston: Imaging in Vascular Access. 07/2017; 8(3)., DOI:10.1007/s13239-017-0317-y

J.R. Weir-McCall, P.M. Yeap, C. Papagiorcopulo, K. Fitzgerald, S.J. Gandy, M. Lambert, J.J.F. Belch, I. Cavin, R. Littleford, J.A. Macfarlane, S.Z. Matthew, R.S. Nicholas, A.D. Struthers, F. Sullivan, S.A. Henderson, R.D. White, J.G. Houston: Reply: The Enigma of Left Ventricular Non-Compaction. Journal of the American College of Cardiology 05/2017; 69(19):2470-2471., DOI:10.1016/j.jacc.2017.02.062

Jonathan R Weir-McCall, Faisel Khan, Deirdre B Cassidy, Arsh Thakur, Jennifer Summersgill, Shona Z Matthew, Fiona Adams, Fiona Dove, Stephen J Gandy, Helen M Colhoun, Jill JF Belch, J Graeme Houston: Effects of inaccuracies in arterial path length measurement on differences in MRI and tonometry measured pulse wave velocity. BMC Cardiovascular Disorders 05/2017; 17(1)., DOI:10.1186/s12872-017-0546-x

Helen McLeod, Ben F. Cox, James Robertson, Robyn Duncan, Shona Matthew, Raj Bhat, Avril Barclay, J. Anwar, Tracey Wilkinson, Andreas Melzer, J. Graeme Houston: Human Thiel-Embalmed Cadaveric Aortic Model with Perfusion for Endovascular Intervention Training and Medical Device Evaluation. CardioVascular and Interventional Radiology 04/2017; 40(3)., DOI:10.1007/s00270-017-1643-z

Jonathan R. Weir-McCall, Phey Ming Yeap, Carla Papagiorcopulo, Kerrie Fitzgerald, Stephen J. Gandy, Matthew Lambert, Jill J.F. Belch, Ian Cavin, Roberta Littleford, Jennifer A. Macfarlane, Shona Z. Matthew, R. Stephen Nicholas, Allan D. Struthers, Frank Sullivan, Shelley A. Waugh, Richard D. White, J. Graeme Houston: Left Ventricular Noncompaction. Journal of the American College of Cardiology 11/2016; 68(20):2157-2165., DOI:10.1016/j.jacc.2016.08.054

Jonathan R Weir-Mccall, Kerrie Fitzgerald, Carla J Papagiorcopulo, Stephen J Gandy, Matthew Lambert, Jill J.F. Belch, Ian Cavin, Roberta Littleford, Jennifer A Macfarlane, Shona Z Matthew, R Stephen Nicholas, Allan D Struthers, Frank M Sullivan, Shelley A Waugh, Richard D White, J Graeme Houston: Prevalence of unrecognized myocardial infarction in a low–intermediate risk asymptomatic cohort and its relation to systemic atherosclerosis. European Heart Journal – Cardiovascular Imaging 08/2016; 18(6)., DOI:10.1093/ehjci/jew155

Stephen J Gandy, Matthew Lambert, Jill Belch, Ian Cavin, Elena Crowe, Roberta Littleford, Jennifer A MacFarlane, Shona Z Matthew, Patricia Martin, R Stephen Nicholas, Allan Struthers, Frank Sullivan, Shelley A Waugh, Richard D White, Jonathan R Weir-McCall, J Graeme Houston: 3T MRI investigation of cardiac left ventricular structure and function in a UK population: The tayside screening for the prevention of cardiac events (TASCFORCE) study. Journal of Magnetic Resonance Imaging 05/2016; 44(5)., DOI:10.1002/jmri.25267

Jonathan R Weir-McCall, Kerrie Fitzgerald, C Papagiorcopulo, Stephen J Gandy, Matthew Lambert, Jill JF Belch, Ian Cavin, Roberta Littleford, Jennifer A MacFarlane, Shona Z Matthew, R Stephen Nicholas, Allan D Struthers, Frank Sullivan, Shelley A Waugh, Richard D White, J Graeme Houston: 015 Prevalence, pattern and significance of late gadolinium enhancement in a healthy asymptomatic cohort. Heart (British Cardiac Society) 05/2016; 102(Suppl 5):A5.3-A5., DOI:10.1136/heartjnl-2016-309680.15

Jonathan R Weir-McCall, Suzanne L Duce, Stephen J Gandy, Shona Z Matthew, Patricia Martin, Deirdre B Cassidy, Lynne McCormick, Jill J F Belch, Allan D Struthers, Helen M Colhoun, J Graeme Houston: Whole body cardiovascular magnetic resonance imaging to stratify symptomatic and asymptomatic atherosclerotic burden in patients with isolated cardiovascular disease. BMC Medical Imaging 02/2016; 16(1):18., DOI:10.1186/s12880-016-0121-4

Stephen J Gandy, Shona Matthew, Sushma Rekhraj, Benjamin Szwejkowski, Elena Crowe, Allan D Struthers, J Graeme Houston: MRI of the left atrium at 3T: Evaluation of measurement reproducibility in healthy volunteers and patients with cardiovascular disease. Acta Radiologica 02/2016; 57(12)., DOI:10.1177/0284185115627386

Suzanne L Duce, Jonathan R Weir-McCall, Stephen J Gandy, Shona Z Matthew, Deirdre B Cassidy, Lynne McCormick, Petra Rauchhaus, Helen Looker, Helen M Colhoun, J Graeme Houston: Cohort comparison study of cardiac disease and atherosclerotic burden in type 2 diabetic adults using whole body cardiovascular magnetic resonance imaging. Cardiovascular Diabetology 09/2015; 14(1):122., DOI:10.1186/s12933-015-0284-2

C MacDonald, S Matthew, M Dunn: A Computational Validation of MRI as a Surveillance Tool forVascular Access in End-Stage Renal Disease.

S.J. Gandy, M. Lambert, J.J.F. Belch, I.D. Cavin, E. Crowe, R. Littleford, J.A. Macfarlane, S.Z. Matthew, P. Martin, R.S. Nicholas, A.D. Struthers, F. Sullivan, S.A. Waugh, R.D. White, J.R. Weir-McCall, J.G. Houston: Technical assessment of whole body angiography and cardiac function within a single MRI examination. Clinical Radiology 03/2015; 10(6)., DOI:10.1016/j.crad.2015.02.003

S Matthew, S J Gandy, R S Nicholas, S A Waugh, E A Crowe, R A Lerski, M H Dunn, J G Houston: Quantitative analysis of cardiac left ventricular variables obtained by MRI at 3 T: A pre- and post-contrast comparison. The British journal of radiology 07/2012; 85(1015):e343-7., DOI:10.1259/bjr/62891785

Conferences/Lectures

Jonathan R Weir-McCall, Matthew Lambert, Jill JF Belch, Ian Cavin, Stephen J Gandy, Roberta Littleford, Jennifer A Macfarlane, Shona Z Matthew, RStephen Nicholas, Allan D Struthers, Frank Sullivan, Shelley A Henderson, Richard D White, J Graeme Houston: 15 No association between systemic arteriosclerosis and atherosclerosis on cardiac MRI and whole body angiography: the tascforce study. British Society of Cardiovascular Imaging/ British Society of Cardiovascular CT (BSCI/BSCCT), Annual Spring meeting, Bournemouth, 18–19th May 2017; 05/2017, DOI:10.1136/heartjnl-2017-311677.15

Helen Mcleod, R.Duncan, B.F.Cox, G.A.Corner, G.A.McLeod, T.Wilkinson, S.Matthew, A.Melzer, J.G.Houston: The future of Thiel embalmed human cadavers as an alternative to training and testing using animals. Dr Hadwen Trust, London; 12/2016

Zi Tew, Kirsty McNeil, Kirsty Butt, Conor MacDonald, Laura Young, Shona Matthew, Deirdre Cassidy, Graeme Houston: Gadolinium-based contrast causing hypersignals in human brain: A systematic review. UKRC 2016, ACC Liverpool; 06/2016

R Murdoch, S Gandy, R Nicholas, G Houston, P Martin, J Muir, S Matthew, P Guntur-Ramkumar, Ian Cavin: Investigating strategies for optimal 31P MRS clinical cardiac at 3T: Initial Results.. EuroCMR, Florence, Italy; 05/2016

Helen Mcleod, B F Cox, J Robertson, R Duncan, R Eisma, T Wilkinson, S Matthew, A Barclay, R Bhat, A Melzer, G Houston: Novel Endovascular Simulation Training With Perfused Thiel Embalmed Human Cadavers. 6th National Scottish Medical Education Conference, Edinburgh; 05/2016

C. MacDonald, N Aristokleous, S Matthew, S Gandy, M Dunn, J.G. Houstopn: Arm postiion alters the geometry of the Brachial Artery and the Basilic Vein. 27th MRWG Annual International Conference, Cincinnati, Ohio, USA; 09/2015

Matthew S, Weir-McCall J, Gandy SJ, Milne WG, and Houston JG: A qualitative assessment of first-pass perfusion bolus timings in the assessment of myocardial ischemia: A magnetic resonance study. MRA 2015, Cincinnati; 09/2015

Conor MacDonald, N Aristokleous, S Matthew, M Dunn, JG Houston: Arm Position Alters the Geometry of the Brachial Artery and Basillic Vein. Magnetic Resonance Angiography 27th Annual International Conference (Sep. 2015); 09/2015

H McLeod, J Robertson, B Cox, R Eisma, A Melzer, G Houston, S Matthew: Functionalised Human Thiel embalmed cadavers-the optimum training model?. 5th National Scottish Medical Education Conference, Edinburgh Scotland; 04/2015

Fitzgerald K, Weir-McCall JR, Papagiorcopulo C, Lambert M, White RD, Gandy SJ, Matthew SZ, Colvin I, MacFarlane J, Sullivan FM, Belch JJ, Struthers AD, Houston JG: An investigation into the underlying rate of silent myocardial infarction in a low-intermediate risk asymptomatic cohort.. ESR 2015, Vienna Austria; 03/2015

Zi Yi Tew, Shona Matthew, Efstratios Kokkalis, J Graeme Houston: Improving blood flow parameters in vascular disease: Flow-rig simulations. SHARP Annual Scientific Meeting, Dunkeld Scotland; 12/2014

Weir-McCall J, Dawson A, Fitzgerald K, papgiocopulo C, Lamber M, White RD, Gandy S, Matthew S, Sullivan FM, Belch JJ, Struthers AD, Houston JG: Left Ventricular Non-compaction: Pathalogical or normal variant?. ECR, Vienna Austria; 03/2014

McLeod H, Cox B, Eisma R, Matthew S, Melzer A, Houston G.: Thiel Embalmed Human Cadaver: Vascular Model Development for Teaching and Training.. College Research Symposium, University of Dundee, Crieff Scotland; 02/2014

DB Cassidy, SJ Gandy, S Duce, S matthew, P Martin, J Weir-McCall, JG Houston: Aortic Pulse Wave Velocity as an Indicator of Cardiovascular Risk in Type - 2 Diabetes.. Scottish Heart and Arterial Risk Prevention, Dunkeld Scotland; 11/2013

Matthew S, Cassidy D, Gandy SJ, Houston JG: High Variability in Signal Intensity during CMRI First Pass Perfusion Imaging when a Standard Dose of Contrast Agent is Used- Blood Pool & Myocardium. ISMRM, Salt Lake City USA; 04/2013

Matthew S, Cassidy D, Gandy SJ, Houston JG: High variability in signal intensity and contrast dynamics during CMRI first pass perfusion imaging when a standard dose of contrast agent is used-tansit times of bolus & peak signal intensity in the blood pool.. ISMRM, Salt Lake City USA; 04/2013

Matthew S, GandySJ, Houston JG: High variability in peak signal intensity and contrast dynamics during first pass perfusion imaging: a CMRI study. 16th Scottish Cardiovascular Forum, London,England; 02/2013

Matthew S, Dunn MH, Houston JG: The challenges of cardiac magnetic resonance imaging.. Scottish Untiversities and Stanford University Collaboration (SU2P) Imaging and Sensing in Medicine and the Life Sciences Workshop, Glasgow, Scotland; 06/2012

matthew S, Gandy SJ, Nicholas RS, Lerski RA, Dunn MH, Houston JG: Assessment of the Clinical Differences at 1.5T between Quantitative Righ and Left Ventricular Volumes and Ejection Fractions using MRI.. Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE), Annual Scientific Meeting, Glasgow, Scotland; 05/2012

Matthew S, Gandy SJ, Nicholas RS, Lerski RA, Dunn MH, Houston JG: Assessment of Clinical Differences at 1.5T between Quantitative Right and Left Ventricular Volumes and Ejection Fractions Using MRI.. Scottish Society for Experimental Medicine (SSEM), Dundee, Scotland; 01/2012

Matthew S, Gandy SJ, Dunn MH, Lerski RA, Houston JG: The effect of contrast agent on quantitative morphological LV parameters at 3T.. Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE), Annual Scientific Meeting, Edinburgh, Scotland; 06/2010

Matthew S, Nicholas RS, Gandy SJ, Waugh SA, Crowe E, Dunn M, Lerski RA, Houston JG: Analysis of Cardiac Left Ventricular Parameters Obtained by Magnetic Resonance Imaging at 3 Tesla: A Pre and Post-contrast Quantitative Comparison.. Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE), Annual Scientific Meeting, Edinburgh, Scotland; 06/2010