Shona Livingstone

+44 (0)1382 383450
Statistician/Epidemiologist

Biography

Shona is an applied statistician (MSc Applied Statistics, St Catherine’s College Oxford. 1990) with a background in pure science (Joint Honours Chemistry and Biochemistry. Imperial College London, 1988). She has worked in both epidemiological and clinical trial settings and a variety of therapeutic areas (cardiothoric surgery, HIV disease surveillance and clinical trials and diabetes).

Since 2008 she has worked at the University of Dundee as a statistician/epidemiologist focusing mainly on Diabetes related complications using Scottish wide epidemiological data, but has also worked on clinical trial data from the Collaborative Atorvastatin Diabetes Study (CARDS), which she first worked on in 2001 while at University College London.

Research

Using data from Scottish data-linkage systems and clinical databases to study the epidemiology of diabetes complications and the safety of drugs.

Secondary analyses of clinical trial data from Collaborative Atorvastatin Diabetes Study (CARDS).

Main statistical expertise: survival analysis and the analysis of longitudinal data.

 

 

 

 

 

 

 

 

 

Lectures and conferences

Diabetes UK 2015 Oral presentation: “Decomposition of the Difference in Life Expectancy Between Adults With and Without Type 1 Diabetes by Age and Cause.”, 12.03.2015.

 

(University of Dundee) College Research Symposium .Oral presentation: Life expectancy in Type 1 Diabetes”. 27th February 2015

 

EASD September 2013. Poster presentation. Life expectancy in type 1 diabetes: a Scottish Registry Linkage study. 25/09/2013.

Publications

Effect of atorvastatin on C-reactive protein and benefits for cardiovascular disease in patients with type 2 diabetes: analyses from the Collaborative Atorvastatin Diabetes Trial. Sabita S. Soedamah-Muthu,1 Shona J. Livingstone,2 Valentine Charlton-Menys,3 D. John Betteridge,4 Graham A. Hitman,5 H. Andrew W. Neil,6 Weihang Bao,7 David A. DeMicco,7 Gregory M. Preston,7 John H. Fuller,8 Coen D.A. Stehouwer,9 Casper G. Schalkwijk,9 Paul N. Durrington,3 Helen M. Colhoun,2 on behalf of the CARDS Investigators. Diabetologia (in press)

 

Estimated Life Expectancy in a Scottish Cohort With Type 1 Diabetes, 2008-2010. Shona J Livingstone, Daniel Levin, Helen C Looker, Robert S Lindsay, Sarah H Wild, Nicola Joss, Graham Leese, Peter Leslie, Rory J McCrimmon, Wendy Metcalfe, John A McKnight, Andrew D Morris, Donald W M Pearson, John R Petrie, Sam Philip, Naveed A Sattar, Jamie P Traynor, Helen M Colhoun. JAMA The Journal of the American Medical Association 01/2015; 313(1):37-44.

 

End stage renal disease and survival in people with diabetes: a national database linkage study. Samira Bell, Emma H Fletcher, Inez Brady, Helen C Looker, Daniel Levin, Nicola Joss, Jamie P Traynor, Wendy Metcalfe, Bryan Conway, Shona Livingstone, Graham Leese, Sam Philip, Sarah Wild, Nynke Halbesma, Naveed Sattar, Robert S Lindsay, John McKnight, Donald Pearson, Helen M Colhoun. QJM: monthly journal of the Association of Physicians 08/2014.

 

Contemporary Risk of Hip Fracture in Type 1 and Type 2 Diabetes: A National Registry Study from Scotland. Eleanor J Hothersall, Shona J Livingstone, Helen C Looker, S Faisal Ahmed, Steve Cleland, Graham P Leese, Robert S Lindsay, John McKnight, Donald Pearson, Sam Philip, Sarah H Wild, Helen M Colhoun. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research 10/2013.

 

Risk of cardiovascular disease and total mortality in adults with type 1 diabetes: Scottish registry linkage study. Shona J Livingstone, Helen C Looker, Eleanor J Hothersall, Sarah H Wild, Robert S Lindsay, John Chalmers, Stephen Cleland, Graham P Leese, John McKnight, Andrew D Morris, Donald W M Pearson, Norman R Peden, John R Petrie, Sam Philip, Naveed Sattar, Frank Sullivan, Helen M Colhoun. PLoS Medicine 10/2012; 9(10):e1001321.

 

Reduced Incidence of Lower-Extremity Amputations in People With Diabetes in Scotland. Brian Kennon, Graham P Leese, Lynda Cochrane, Helen Colhoun, Sarah Wild, Duncan Stang, Naveed Sattar, Donald Pearson, Robert S Lindsay, Andrew D Morris, Shona Livingstone, Matthew Young, John McKnight, Scott Cunningham. Diabetes care 09/2012; 35(12).

 

Hospitalised hip fracture risk with rosiglitazone and pioglitazone use compared with other glucose-lowering drugs. H M Colhoun, S J Livingstone, H C Looker, A D Morris, S H Wild, R S Lindsay, C Reed, P T Donnan, B Guthrie, G P Leese, J McKnight, D W M Pearson, E Pearson, J R Petrie, S Philip, N Sattar, F M Sullivan, P McKeigue. Diabetologia 09/2012; 55(11):2929-2937.

 

A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts. N van Leeuwen, G Nijpels, M L Becker, H Deshmukh, K Zhou, B H C Stricker, A G Uitterlinden, A Hofman, E van 't Riet, C N A Palmer, [......], R A Calle, A Neil, G Hitman, S J Livingstone, H Colhoun, R R Holman, M I McCarthy, J M Dekker, L M 't Hart, E R Pearson. Diabetologia 03/2012; 55(7):1971-7.

 

Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a). Harshal A Deshmukh, Helen M Colhoun, Toby Johnson, Paul M McKeigue, D John Betteridge, Paul N Durrington, John H Fuller, Shona Livingstone, Valentine Charlton-Menys, Andrew Neil, [......], Aurobindo Chatterjee, Craig Hyde, Roberto A Calle, David A Demicco, Stella Trompet, Iris Postmus, Ian Ford, J Wouter Jukema, Mark Caulfield, Graham A Hitman. The Journal of Lipid Research 02/2012; 53(5):1000-11.

 

Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: Importance of Lp(a). Deshmukh HA, Colhoun HM, Johnson T, McKeigue PM, Betteridge DJ, Durrington PN, Fuller JH, Livingstone S, Charlton-Menys V, Neil A, [......], Chatterjee A, Hyde C, Calle RA, Demicco DA, Trompet S, Postmus I, Ford I, Jukema JW, Caulfield M, Hitman GA. The Journal of Lipid Research 02/2012.

 

Total Soluble and Endogenous Secretory Receptor for Advanced Glycation End Products as Predictive Biomarkers of Coronary Heart Disease Risk in Patients With Type 2 Diabetes. Helen M Colhoun, D John Betteridge, Paul Durrington, Graham Hitman, Andrew Neil, Shona Livingstone, Valentine Charlton-Menys, Weihang Bao, David A Demicco, Gregory M Preston, Harshal Deshmukh, Kathryn Tan, John H Fuller. Diabetes 07/2011; 60(9):2379-85.

 

Effect of socioeconomic status on mortality among people with type 2 diabetes: a study from the Scottish Diabetes Research Network Epidemiology Group. Jeremy J Walker, Shona J Livingstone, Helen M Colhoun, Robert S Lindsay, John A McKnight, Andrew D Morris, John R Petrie, Sam Philip, Naveed Sattar, Sarah H Wild. Diabetes care 03/2011; 34(5):1127-32.

 

The effect of atorvastatin therapy on tumour necrosis factor-? and vascular adhesion molecules in patients with type 2 diabetes mellitus with no prior history of coronary heart disease. Sabita S Soedamah-Muthu, Val Charlton-Menys, Weihang Bao, Casper Schalkwijk, Coen Da Stehouwer, Helen M Colhoun, D John Betteridge, Paul N Durrington, Graham A Hitman, H Andrew W Neil, Shona J Livingstone, John H Fuller. The British Journal of Diabetes & Vascular Disease 01/2011; 11(6):288-297.

 

Metformin in type 1 diabetes reduces insulin requirements without significantly improving glycaemic control. Reply to Schatz H [letter]. S Vella, L Buetow, P Royle, S Livingstone, J R Petrie. Diabetologia 10/2010; 54(1):203-4.

 

The use of metformin in type 1 diabetes: a systematic review of efficacy. S Vella, L Buetow, P Royle, S Livingstone, H M Colhoun, J R Petrie. Diabetologia 05/2010; 53(5):809-20.

 

Effects of atorvastatin on kidney outcomes and cardiovascular disease in patients with diabetes: an analysis from the Collaborative Atorvastatin Diabetes Study (CARDS). Colhoun HM, Betteridge DJ, Durrington PN, Hitman GA, Neil HA, Livingstone SJ, Charlton-Menys V, DeMicco DA, Fuller JH, CARDS Investigators, [......], Winocour P, Fraser J, O'Brien IA, Singh BM, Fulton JA, Millar L, Warner S, Harvey JN, Jennings P, Thow J. American Journal of Kidney Diseases 11/2009; 54(5):810-819.

 

Effects of Atorvastatin on Kidney Outcomes and Cardiovascular Disease in Patients With Diabetes: An Analysis From the Collaborative Atorvastatin Diabetes Study (CARDS). Helen M Colhoun, D John Betteridge, Paul N Durrington, Graham A Hitman, H Andrew W Neil, Shona J Livingstone, Valentine Charlton-Menys, David A DeMicco, John H Fuller. American Journal of Kidney Diseases 06/2009; 54(5):810-9.

 

Targets of statin therapy: LDL cholesterol, non-HDL cholesterol, and apolipoprotein B in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS). Valentine Charlton-Menys, D John Betteridge, Helen Colhoun, John Fuller, Michael France, Graham A Hitman, Shona J Livingstone, H Andrew W Neil, Connie B Newman, Michael Szarek, David A DeMicco, Paul N Durrington.Clinical Chemistry 02/2009; 55(3):473-80. · 7.77 Impact Factor

 

Apolipoproteins, cardiovascular risk and statin response in type 2 diabetes: the Collaborative Atorvastatin Diabetes Study (CARDS). V Charlton-Menys, D. J. Betteridge, H Colhoun, J Fuller, M France, G. A. Hitman, S. J. Livingstone, H. A. W. Neil, C. B. Newman, M Szarek, D. A. DeMicco, P. N. Durrington. Diabetologia 02/2009; 52(2).

 

Stroke prediction and stroke prevention with atorvastatin in the Collaborative Atorvastatin Diabetes Study (CARDS). G A Hitman, H Colhoun, C Newman, M Szarek, D J Betteridge, P N Durrington, J Fuller, S Livingstone, H A W Neil. Diabetic Medicine 12/2007; 24(12):1313-21.