Roland Wolf

+44 (0)1382 383134
Professor of Pharmacology

Publications

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials
3/2019, Drug Metabolism and Disposition
Research Output: Contribution To Journal > Article

Defining the contribution of CYP1A1 and CYP1A2 to drug metabolism using humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 KO mice
5/2019, Drug Metabolism and Disposition
Research Output: Contribution To Journal > Article

Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
1/2019, Toxicology and Applied Pharmacology
Research Output: Contribution To Journal > Article

Constitutive androstane receptor 1 is constitutively bound to chromatin and ‘primed’ for transactivation in hepatocytes
10/2018, Molecular Pharmacology
Research Output: Contribution To Journal > Article

Discovery of common and rare genetic risk variants for colorectal cancer
10/2018, Nature Genetics
Research Output: Contribution To Journal > Article

Identification of novel pathways of osimertinib disposition and potential implications for the outcome of lung cancer therapy
11/2017, Clinical Cancer Research
Research Output: Contribution To Journal > Article

Cytochrome b5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation : studies in hepatic cytochrome b5 /P450 reductase null (HBRN) mice
9/2017, Archives of Toxicology
Research Output: Contribution To Journal > Article

Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk : A case-control study in unselected white European populations
5/2017, PLoS ONE
Research Output: Contribution To Journal > Article

Measuring in vivo responses to endogenous and exogenous oxidative stress using a novel haem oxygenase 1 reporter mouse
7/2017, Journal of Physiology
Research Output: Contribution To Journal > Article

Novel Pathways Of Ponatinib Disposition Catalysed By CYP1A1 Involving Generation Of Potentially Toxic Metabolites
8/2017, Journal of Pharmacology and Experimental Therapeutics
Research Output: Contribution To Journal > Article

View full profile on research portal

Press

Gene helps predict which ovarian cancer sufferers will benefit most from chemotherapy

Gillian Smith, Michael Ng, Simon Herrington, Michelle Ferguson & Roland Wolf

19/09/12

1 item of media coverage

Press/Media: Research



View full profile on research portal

Activities

14th North American ISSX Meeting

Roland Wolf (Participant)
22 Oct 200626 Oct 2006

Activity: Participating in or organising an event typesParticipation in conference

Activity Type: Attendance

Newcastle Pathology 2005: 3rd Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain and Ireland

Roland Wolf (Participant)
5 Jul 20058 Jul 2005

Activity: Participating in or organising an event typesParticipation in conference

Activity Type: Attendance

British Society for Investigative Dermatology Annual Meeting

Roland Wolf (Participant)
7 Apr 20039 Apr 2003

Activity: Participating in or organising an event typesParticipation in conference

Activity Type: Attendance

184th Meeting of the Pathological Society of Great Britain and Ireland

Roland Wolf (Participant)
2 Jul 20025 Jul 2002

Activity: Participating in or organising an event typesParticipation in conference

Activity Type: Attendance

51st Annual Meeting of the American Society of Human Genetics

Roland Wolf (Participant)
12 Oct 200116 Oct 2001

Activity: Participating in or organising an event typesParticipation in conference

Activity Type: Attendance

View full profile on research portal