Nicola Morrice

Postdoctoral Research Assistant

Biography

Research Assistant, Institute of Medical Sciences, University of Aberdeen, 2017 (supervised by Professor Mirela Delibegovic)

PhD Medical Sciences, Institute of Medical Sciences and Centre for Genome Enabled Biology and Medicine, University of Aberdeen, 2013-2017 (supervised by Dr Nimesh Mody)

Bsc (Hons) Biochemistry, University of Dundee, 2009-2013 (final year research project supervised by Professor Tom Owen-Hughes, Wellcome Trust Centre for Gene Regulation and Expression)

Research project, iGEM, Division of Molecular Microbiology, University of Dundee, 2012 (supervised by Professor Frank Sargent and Professor Tracy Palmer)

Publications

Le Sommer S, Morrice N, Pesaresi M, Thompson D, Vickers MA, Murray GI, Mody N, Neel BG, Bence KK, Wilson HM, Delibegovic M (2017), Deficiency in protein tyrosine phosphatase PTP1B shortens lifespan and leads to development of acute leukemia, Cancer Research, doi: 10.1158/008-5472.CNA-17-0946

Thompson D, Morrice N, Grant L, Le Sommer S, Lees EK, Mody N, Wilson HM, Delibegovic M (2017), Pharmacological inhibition of protein tyrosine phosphatase 1B (PTP1B) protects against atherosclerotic plaque formation in the LDLR-/- mouse model of atherosclerosis, Clinical Science, doi: 10.1042/CS20171066

Lees EK, Banks R, Cook C, Hill S, Morrice N, Grant L, Mody N, Delibegovic M (2017), Direct comparison of methionine restriction with leucine restriction on the metabolic health of C57BL/6J mice, Scientific Reports, 7, 9977

Thompson D, Morrice N, Grant L, Le Sommer S, Ziegler K, Whitfield P, Mody N, Wilson H, Delibegovic M, Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE-/- mouse model of atherosclerosis with alterations in IL10/AMPK? pathway, Molecular Metabolism (2017), doi: 10.1016/j.molmet.2017.06.003

Morrice N, Mcilroy GD, Tammireddy SR, Reekie J, Shearer KD, Doherty M, Delibegovic M, Whitfield P, Mody N (2017), Elevated Fibroblast Growth Factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice, Scientific Reports, 3 (7): 43782

Shearer KD, Morrice N, Henderson C, Reekie J, Mcilroy GD, McCaffery PJ, Delibegovic M, Mody N (2015), Fenretinide prevents obesity in aged female mice in association with increased retinoid and estrogen signalling, Obesity, 23 (8): 1655-62