Michael Murphy

+44 (0)1382 383541
Clinical Reader

Biography

Michael Murphy BA(Mod) MB BCh BAO MA MD FRCP FRCPath ARCM holds degrees in biochemistry and medicine from Trinity College Dublin, and completed higher specialist training in clinical biochemistry in Dublin and Glasgow. He was appointed to the University of Dundee in 2002 where he is Reader in Biochemical Medicine and Director of Admissions. He also co-ordinates the student-selected strand of the Dundee undergraduate curriculum as SSC Convenor. He is Editor-in-Chief of the Annals of Clinical Biochemistry, the UK specialty journal for clinical biochemists, and lead author of a bestselling textbook of clinical biochemistry.

Research

Editor-in-Chief of the Annals of Clinical Biochemistry. Published by SAGE Publications, this is the fully peer-reviewed international journal of the Association for Clinical Biochemistry and Laboratory Medicine. The Annals is also the official journal of NVKC (de Nederlandse Vereniging voor Klinische Chemie) and JSCC (Japan Society of Clinical Chemistry), and the AACB (Australasian Association of Clinical Biochemists) promotes subscriptions to the Annals to their members via a mutual agreement. It accepts papers that contribute to knowledge in all fields of laboratory medicine, especially those pertaining to the understanding, diagnosis and treatment of human disease.

Twitter: @AnnClinBiochem

Research output reflects a broad range of interests, with approximately seventy publications on diverse topics.

Main research focus currently is prevalence of declared disability in undergraduate and postgraduate medicine in the UK, using the linked datasets in the UK Medical Education Database (UKMED).

With colleagues in Dundee he has used record linkage to address a range of specific questions, e.g. defining the association between raised triglycerides and pancreatitis, examining the effectiveness of statins in a 'real-world' setting, assessing the impact of eGFR reporting on prescribing.

As SSC Convenor he has spearheaded SSC initiatives both locally and nationally. Outputs include a series of papers and the chapter on SSCs in the Oxford Textbook of Medical Education.

He maintains links with investigators at the EarlyBird Study in Plymouth, specifically focusing on what can be learnt from studies of gender differences in insulin resistance in childhood. The title of his MD thesis was "Gender differences in insulin resistance in prepubertal British children."

Other strands of activity relate to biochemical practice, e.g. reflex/reflective ("add-on") testing, evidence-based action limits and personalised laboratory medicine.

Books

The sixth edition of Clinical Biochemistry: An Illustrated Colour Text by Michael Murphy, Rajeev Srivastava and Kevin Deans was published by Elsevier in 2018. First published in 1995, the book has been translated into nine languages and estimated global sales are approximately 75,000.

Case Studies in Clinical Biochemistry by Michael Murphy, Rajeev Srivastava and Allan Gaw was published in 2012. The book has been incorporated in its entirety into the online sixth edition of the world-famous Tietz: Fundamentals of Clinical Chemistry and Molecular Diagnostics - the 'bible' for clinical chemists everywhere.

Publications

Most cited papers (from ResearcherID, accessed June 2018):

  1. Girls at five are intrinsically more insulin resistant than boys: The programming hypotheses revisited: The EarlyBird study. Murphy MJ, Metcalf BS, Voss LD, et al. Pediatrics 2004; 113: 82-86.
    Times Cited: 107
     
  2. Increased mortality and morbidity in mild primary hyperparathyroid patients: The Parathyroid Epidemiology & Audit Research Study (PEARS). Yu N, Donnan PT, Flynn RWV, et al. Clin Endocrinol 2010; 73: 30-34.
    Times Cited: 85
     
  3. Increasing prevalence and incidence of thyroid disease in Tayside, Scotland: the Thyroid Epidemiology Audit and Research Study (TEARS). Leese GP, Flynn RV, Jung RT, et al. Clin Endocrinol 2008; 68: 311-316.
    Times Cited: 73
     
  4. The relative contributions of birth weight, weight change, and current weight to insulin resistance in contemporary 5-year-olds: The EarlyBird study. Wilkin TJ, Metcalf BS, Murphy MJ, et al. Diabetes 2002; 51: 3468-3472.
    Times Cited: 64
     
  5. Epidemiology of primary hyperparathyroidism in Tayside, Scotland, UK. Yu N, Donnan PT, Murphy MJ, et al. Clin Endocrinol 2009; 71: 485-493.
    Times Cited: 63
     
  6. Lipid-modifying therapies and risk of pancreatitis: a meta-analysis. Preiss D, Tikkanen MJ, Welsh P, et al. JAMA 2012; 308: 804-811.
    Times Cited: 57
     
  7. Age- and gender-specific TSH reference intervals in people with no obvious thyroid disease in Tayside, Scotland: The Thyroid Epidemiology, Audit, and Research Study (TEARS). Vadiveloo T, Donnan PT, Murphy MJ, et al. JCEM 2013; 98: 1147-1153.
    Times Cited: 48
     
  8. The gender insulin hypothesis: why girls are born lighter than boys, and the implications for insulin resistance. Wilkin TJ, Murphy MJ. Int J Obes 2006; 30: 1056-1061.
    Times Cited: 47
     
  9. Adiponectin in childhood. Jeffery AN, Murphy MJ, Metcalf BS, et al. Int J Pediatr Obes 2008; 3: 130-140
    Times Cited: 42
     
  10. Effectiveness of statins on total cholesterol and cardiovascular disease and all-cause mortality in osteoarthritis and rheumatoid arthritis. Sheng X, Murphy MJ, MacDonald TM, et al. J Rheumatol 2012; 39: 32-40.
    Times Cited: 39