Jean-Christophe Bourdon

+44 (0)1382 383285
Senior Lecturer

Publications

Nguyen Van Long, F, Lardy-Cleaud, A, Bray, S, Chabaud, S, Dubois, T, Diot, A, Thompson, AM, Bourdon, J-C, Perol, D, Bouvet, P, Diaz, J-J & Marcel, V 2018,

'Druggable Nucleolin Identifies Breast Tumours Associated with Poor Prognosis That Exhibit Different Biological Processes' Cancers, vol. 10, no. 10, 390, pp. 1-11.
https://doi.org/10.3390/cancers10100390

Research output: Contribution To Journal



Ko, CJ, Myung, P, Leffell, DJ & Bourdon, J-C 2018,

'Cutaneous immunohistochemical staining pattern of p53β isoforms' Journal of Clinical Pathology.
https://doi.org/10.1136/jclinpath-2018-205098

Research output: Contribution To Journal



Pizzorno, A, Dubois, J, Machado, D, Cartet, G, Traversier, A, Julien, T, Lina, B, Bourdon, J-C, Rosa-Calatrava, M & Terrier, O 2018,

'Influenza A viruses alter the stability and antiviral contribution of host E3-ubiquitin ligase Mdm2 during the time-course of infection' Scientific Reports, vol. 8, 3746, pp. 1-13.
https://doi.org/10.1038/s41598-018-22139-6

Research output: Contribution To Journal



Revin, VV, Gromova, NV, Revina, ES, Grunyushkin, IP, Tychkov, AY, Samonova, AY, Kukina, AN, Moskovkin, AA, Bourdon, JC & Zhelev, N 2018,

'The effect of experimental hyperoxia on erythrocytes’ oxygen-transport function' Biotechnology and Biotechnological Equipment.
https://doi.org/10.1080/13102818.2017.1414633

Research output: Contribution To Journal



Revin, VV, Klenova, NA, Gromova, NV, Grunyushkin, IP, Solomadin, IN, Tychkov, AY, Pestryakova, AA, Sadykhova, AV, Revina, ES, Prosnikova, KV, Bourdon, J-C & Zhelev, N 2017,

'Physical and Chemical Processes and the Morphofunctional Characteristics of Human Erythrocytes in Hyperglycaemia' Frontiers in Physiology, vol. 8, 606.
https://doi.org/10.3389/fphys.2017.00606

Research output: Contribution To Journal



Trovato, MC, Ruggeri, RM, Guzzo, E, Certo, R, Alibrandi, A, Scifo, S, Scardigno, M, Vitarelli, E, Arena, G, Gambadoro, O, Catalano, N, Bourdon, JC, Galletti, B, Galletti, F & Cavallari, V 2017,

'Expression of P53 and isoforms in bening and malignant lesions of the head and neck' Histology and Histopathology, vol. 32, no. 4, pp. 371-377.
https://doi.org/10.14670/HH-11-802

Research output: Contribution To Journal



Trovato, MC, Ruggeri, RM, Scardigno, M, Sturniolo, G, Vita, R, Vitarelli, E, Arena, G, Gambadoro, O, Sturniolo, G, Trimarchi, F, Benvenga, S, Bourdon, J-C & Cavallari, V 2016,

'Immunoreactions for P53 isoforms are associated with ultrastructural proliferative profiles in benign thyroid nodules' Histology and Histopathology, vol. 31, no. 10, 11736, pp. 1079-1087.
https://doi.org/10.14670/HH-11-736

Research output: Contribution To Journal



Gadea, G, Arsic, N, Fernandes, K, Diot, A, Joruiz, SM, Abdallah, S, Meuray, V, Vinot, S, Anguille, C, Remenyi, J, Khoury, MP, Quinlan, PR, Purdie, CA, Jordan, LB, Fuller-Pace, FV, de Toledo, M, Cren, M, Thompson, AM, Bourdon, J-C & Roux , P 2016,

'TP53 drives invasion through expression of its ∆133p53β variant' e Life, vol. 5, e14734, pp. 1-26.
https://doi.org/10.7554/e Life.14734

Research output: Contribution To Journal



Joruiz, SM & Bourdon, J-C 2016,

'p53 isoforms key regulators of the cell fate decision' Cold Spring Harbor Perspectives in Medicine, vol. 6, no. 8, a026583.
https://doi.org/10.1101/cshperspect.a026039

Research output: Contribution To Journal



Mao, X, Gauche, C, Coughtrie, MWH, Bui, C, Gulberti, S, Merhi-Soussi, F, Ramalanjaona, N, Bertin-Jung, I, Diot, A, Dumas, D, De Freitas Caires, N, Thompson, AM, Bourdon, J-C, Ouzzine, M & Fournel-Gigleux, S 2016,

'The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer' Oncogene, vol. 35, pp. 5043-5055.
https://doi.org/10.1038/onc.2016.44

Research output: Contribution To Journal



Marcel, V, Fernandes, K, Terrier, O, Lane, DP & Bourdon, J-C 2014,

'Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response' Cell Death & Differentiation, vol. 21, pp. 1377-1387.
https://doi.org/10.1038/cdd.2014.73

Research output: Contribution To Journal



Surget, S, Khoury, MP & Bourdon, J-C 2014,

'Uncovering the role of p53 splice variants in human malignancy: a clinical perspective' Onco Targets and Therapy, vol. 7, pp. 57-68.
https://doi.org/10.2147/OTT.S53876

Research output: Contribution To Journal



Bourdon, JC 2014,

'p53 isoforms change p53 paradigm' Molecular and Cellular Oncology, vol. 1, no. 4, pp. e969136.
https://doi.org/10.4161/23723548.2014.969136

Research output: Contribution To Journal



Marcel, V, Ghayad, SE, Belin, S, Therizols, G, Morel, A-P, Solano-Gonzàlez, E, Vendrell, JA, Hacot, S, Mertani, HC, Albaret, MA, Bourdon, J-C, Jordan, L, Thompson, A, Tafer, Y, Cong, R, Bouvet, P, Saurin, J-C, Catez, F, Prats, A-C, Puisieux, A & Diaz, J-J 2013,

'p53 acts as a safeguard of translational control by regulating fibrillarin and r RNA methylation in cancer' Cancer Cell, vol. 24, no. 3, pp. 318-330.
https://doi.org/10.1016/j.ccr.2013.08.013

Research output: Contribution To Journal



Terrier, O, Diederichs, A, Dubois, J, Cartet, G, Lina, B, Bourdon, J-C & Rosa-Calatrava, M 2013,

'Influenza NS1 interacts with p53 and alters its binding to p53-responsive genes, in a promoter-dependent manner' FEBS Letters, vol. 587, no. 18, pp. 2965-2971.
https://doi.org/10.1016/j.febslet.2013.08.006

Research output: Contribution To Journal



Simeonova, I, Jaber, S, Draskovic, I, Bardot, B, Fang, M, Bouarich-Bourimi, R, Lejour, V, Charbonnier, L, Soudais, C, Bourdon, J-C, Huerre, M, Londono-Vallejo, A & Toledo, F 2013,

'Mutant mice lacking the p53 C-terminal domain model telomere syndromes' Cell Reports, vol. 3, no. 6, pp. 2046-2058.
https://doi.org/10.1016/j.celrep.2013.05.028

Research output: Contribution To Journal



Terrier, O, Textoris, J, Carron, C, Marcel, V, Bourdon, J-C & Rosa-Calatrava, M 2013,

'Host micro RNA molecular signatures associated with human H1N1 and H3N2 influenza A viruses reveal an unanticipated antiviral activity for mi R-146a' Journal of General Virology, vol. 94, no. 5, pp. 985-995.
https://doi.org/10.1099/vir.0.049528-0

Research output: Contribution To Journal



Bernard, H, Garmy-Susini, B, Ainaoui, N, Van Den Berghe, L, Peurichard, A, Javerzat, S, Bikfalvi, A, Lane, DP, Bourdon, JC & Prats, A-C 2013,

'The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression' Oncogene, vol. 32, no. 17, pp. 2150-2160.
https://doi.org/10.1038/onc.2012.242

Research output: Contribution To Journal



Terrier, O, Bourdon, J-C & Rosa-Calatrava, M 2013,

'p53 Protein Isoforms: Key Regulators in the Front Line of Pathogen Infections?' PLo S Pathogens, vol. 9, no. 4, pp. e1003246.
https://doi.org/10.1371/journal.ppat.1003246

Research output: Contribution To Journal



Allende-Vega, N, Dayal, S, Agarwala, U, Sparks, A, Bourdon, J-C & Saville, MK 2013,

'p53 is activated in response to disruption of the pre-m RNA splicing machinery' Oncogene, vol. 32, no. 1, pp. 1-14.
https://doi.org/10.1038/onc.2012.38

Research output: Contribution To Journal



Marcel, V, Khoury, MP, Fernandes, K, Diot, A, Lane, DP & Bourdon, J-C 2013,

Detecting p53 isoforms at protein level. in S Deb & SP Deb (eds), p53 protocols. Methods in Molecular Biology, vol. 962, Humana Press, Totowa, N.J., pp. 15-29.
https://doi.org/10.1007/978-1-62703-236-0_2

Research output: Contribution To Book Anthology



Khoury, MP, Marcel, V, Fernandes, K, Diot, A, Lane, DP & Bourdon, J-C 2013,

Detecting and quantifying p53 isoforms at m RNA level in cell lines and tissues. in S Deb & SP Deb (eds), p53 protocols. Methods in Molecular Biology, vol. 962, Humana Press, Totowa, N.J., pp. 1-14.
https://doi.org/10.1007/978-1-62703-236-0_1

Research output: Contribution To Book Anthology



Silden, E, Hjelle, SM, Wergeland, L, Sulen, A, Andresen, V, Bourdon, J-C, Micklem, DR, Mc Cormack, E & Gjertsen, BT 2013,

'Expression of TP53 isoforms p53β or p53γ enhances chemosensitivity in TP53(null) cell lines' PLo S ONE, vol. 8, no. 2, e56276.
https://doi.org/10.1371/journal.pone.0056276

Research output: Contribution To Journal



Dichtel-Danjoy, M-L, Ma, D, Dourlen, P, Chatelain, G, Napoletano, F, Robin, M, Corbet, M, Levet, C, Hafsi, H, Hainaut, P, Ryoo, HD, Bourdon, J-C & Mollereau, B 2013,

'Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation' Cell Death & Differentiation, vol. 20, no. 1, pp. 108-116.
https://doi.org/10.1038/cdd.2012.100

Research output: Contribution To Journal



Terrier, O, Marcel, V, Cartet, G, Lane, DP, Lina, B, Rosa-Calatrava, M & Bourdon, J-C 2012,

'Influenza A viruses control expression of proviral human p53 isoforms p53β and Delta133p53α' Journal of Virology, vol. 86, no. 16, pp. 8452-8460.
https://doi.org/10.1128/JVI.07143-11

Research output: Contribution To Journal



Camus, S, Menendez, S, Fernandes, K, Kua, N, Liu, G, Xirodimas, DP, Lane, DP & Bourdon, J-C 2012,

'The p53 isoforms are differentially modified by Mdm2' Cell Cycle, vol. 11, no. 8, pp. 1646-1655.
https://doi.org/10.4161/cc.20119

Research output: Contribution To Journal



Marcel, V, Petit, I, Murray-Zmijewski, F, Goullet De Rugy, T, Fernandes, K, Meuray, V, Diot, A, Lane, DP, Aberdam, D & Bourdon, J-C 2012,

'Diverse p63 and p73 isoforms regulate Delta 133p53 expression through modulation of the internal TP53 promoter activity' Cell Death & Differentiation, vol. 19, no. 5, pp. 816-826.
https://doi.org/10.1038/cdd.2011.152

Research output: Contribution To Journal



Ånensen, N, Hjelle, SM, Van Belle, W, Haaland, I, Silden, E, Bourdon, J-C, Hovland, R, Taskén, K, Knappskog, S, Lønning, PE, Bruserud, O & Gjertsen, BT 2012,

'Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia' Oncogene, vol. 31, no. 12, pp. 1533-1545.
https://doi.org/10.1038/onc.2011.348

Research output: Contribution To Journal



Watt, S, Pourreyron, C, Purdie, K, Hogan, C, Cole, CL, Foster, N, Pratt, N, Bourdon, J-C, Appleyard, V, Murray, K, Thompson, A, Mao, X, Mein, C, Bruckner-Tuderman, L, Evans, A, Mc Grath, JA, Proby, CM, Foerster, J, Leigh, I & South, A 2011,

'Integrative m RNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma' Oncogene, vol. 30, no. 46, pp. 4666-4677.
https://doi.org/10.1038/onc.2011.180

Research output: Contribution To Journal



Khoury, MP & Bourdon, J-C 2011,

'p53 isoforms: an intracellular microprocessor?' Genes and Cancer, vol. 2, no. 4, pp. 453-465.
https://doi.org/10.1177/1947601911408893

Research output: Contribution To Journal



Terrier, O, Josset, L, Textoris, J, Marcel, V, Cartet, G, Ferraris, O, N'Guyen, C, Lina, B, Diaz, J-J, Bourdon, J-C & Rosa-Calatrava, M 2011,

'Cellular transcriptional profiling in human lung epithelial cells infected by different subtypes of influenza A viruses reveals an overall down-regulation of the host p53 pathway' Virology Journal, vol. 8, 285.
https://doi.org/10.1186/1743-422X-8-285

Research output: Contribution To Journal



Moore, HC, Johnston, M, Nicol, SM, Bourdon, J-C, Thompson, AM, Hutvagner, G & Fuller-Pace, FV 2011,

'An evolutionarily conserved, alternatively spliced, intron in the p68/DDX5 DEAD-box RNA helicase gene encodes a novel mi RNA' RNA: a Publication of the RNA Society, vol. 17, no. 4, pp. 555-562.
https://doi.org/10.1261/rna.2591611

Research output: Contribution To Journal



Marcel, V, Olivier, M, Mollereau, B, Hainaut, P & Bourdon, J-C 2011,

'First International p53 Isoforms Meeting: 'p53 isoforms through evolution: from identification to biological function'' Cell Death & Differentiation, vol. 18, no. 3, pp. 563-564.
https://doi.org/10.1038/cdd.2010.156

Research output: Contribution To Journal



Ghayad, SE, Belin, S, Morel, A-P, Hacot, S, Mertani, HC, Vendrell, J, Bourdon, J-C, Prats, A-C, Puisieux, A & Diaz, J-J 2011,

'Involvement of p53 in ribosomal RNA processing and translational control' Bulletin du Cancer, vol. 98, no. S1, pp. S30-S30.

Research output: Contribution To Journal



Aoubala, M, Murray-Zmijewski, F, Khoury, MP, Fernandes, K, Perrier, S, Bernard, H, Prats, A-C, Lane, DP & Bourdon, J-C 2011,

'p53 directly transactivates Delta 133p53 alpha, regulating cell fate outcome in response to DNA damage' Cell Death & Differentiation, vol. 18, no. 2, pp. 248-258.
https://doi.org/10.1038/cdd.2010.91

Research output: Contribution To Journal



Marcel, V, Dichtel-Danjoy, M-L, Sagne, C, Hafsi, H, Ma, D, Ortiz-Cuaran, S, Olivier, M, Hall, J, Mollereau, B, Hainaut, P & Bourdon, J-C 2011,

'Biological functions of p53 isoforms through evolution: lessons from animal and cellular models' Cell Death & Differentiation, vol. 18, no. 12, pp. 1815-1824.
https://doi.org/10.1038/cdd.2011.120

Research output: Contribution To Journal



Bourdon, J-C, Khoury, MP, Diot, A, Baker, L, Fernandes, K, Aoubala, M, Quinlan, P, Purdie, CA, Jordan, LB, Prats, A-C, Lane, DP & Thompson, AM 2011,

'p53 mutant breast cancer patients expressing p53 gamma have as good a prognosis as wild-type p53 breast cancer patients' Breast Cancer Research, vol. 13, no. 1, R7, pp. -.
https://doi.org/10.1186/bcr2811

Research output: Contribution To Journal



Dalvai, M, Mondesert, O, Bourdon, J-C, Ducommun, B & Dozier, C 2011,

'Cdc25B is negatively regulated by p53 through Sp1 and NF-Y transcription factors' Oncogene, vol. 30, no. 19, pp. 2282-2288.
https://doi.org/10.1038/onc.2010.588

Research output: Contribution To Journal



Bergoglio, V, Pillaire, M-J, Allera-Moreau, C, Vidal-Fernandez, A, Bieth, A, Oumouhou, N, Lepage, B, Gordien, K, Rouquette, I, Brouchet, L, Delisle, M-B, Wood, R, Bourdon, J-C, Roche, H, Selves, J, Guimbaud, R, Martin, AL, Tourriere, H, Bianco, J, Pasero, P, Hoffmann, J-S & Cazaux, C 2011,

'The non-conventional replication of DNA as a prognosis signature in solid cancers' Bulletin du Cancer, vol. 98, pp. S40 .

Research output: Contribution To Journal



Moore, HC, Jordan, LB, Bray, SE, Baker, L, Quinlan, PR, Purdie, CA, Thompson, AM, Bourdon, J-C & Fuller-Pace, FV 2010,

'The RNA helicase p68 modulates expression and function of the Delta 133 isoform(s) of p53, and is inversely associated with Delta 133p53 expression in breast cancer' Oncogene, vol. 29, no. 49, pp. 6475-6484.
https://doi.org/10.1038/onc.2010.381

Research output: Contribution To Journal



Fujita, K, Horikawa, I, Mondal, AM, Jenkins, LMM, Appella, E, Vojtesek, B, Bourdon, J-C, Lane, DP & Harris, CC 2010,

'Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence' Nature Cell Biology, vol. 12, no. 12, pp. 1205-U196.
https://doi.org/10.1038/ncb2123

Research output: Contribution To Journal



Marcel, V, Perrier, S, Aoubala, M, Ageorges, S, Groves, MJ, Diot, A, Fernandes, K, Tauro, S & Bourdon, J-C 2010,

'Delta 160p53 is a novel N-terminal p53 isoform encoded by Delta 133p53 transcript' FEBS Letters, vol. 584, no. 21, pp. 4463-4468.
https://doi.org/10.1016/j.febslet.2010.10.005

Research output: Contribution To Journal



Mc Kenzie, L, King, S, Marcar, L, Nicol, S, Dias, S, Schumm, K, Robertson, P, Bourdon, J-C, Perkins, N, Fuller-Pace, F & Meek, DW 2010,

'p53-dependent repression of polo-like kinase-1 (PLK1)' Cell Cycle, vol. 9, no. 20, pp. 4200-4212.
https://doi.org/10.4161/cc.9.20.13532

Research output: Contribution To Journal



Lemee, F, Bergoglio, V, Fernandez-Vidal, A, Machado-Silva, A, Pillaire, M-J, Bieth, A, Gentil, C, Baker, L, Martin, A-L, Leduc, C, Lam, E, Magdeleine, E, Filleron, T, Oumouhou, N, Kaina, B, Seki, M, Grimal, F, Lacroix-Triki, M, Thompson, A, Roche, H, Bourdon, J-C, Wood, RD, Hoffmann, J-S & Cazaux, C 2010,

'DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability' Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 30, pp. 13390-13395.
https://doi.org/10.1073/pnas.0910759107

Research output: Contribution To Journal



Cazaux, CC, Bergoglio, VB, Lemee, FL, Vidal-Fernandez, AVF, Machado, AM, Martin, ALM, Roche, HR, Wood, RDW, Bourdon, JBC & Hoffmann, JSH 2010,

'POLQ up-regulation is associated with poor survival in breast cancer, perturbs DNA replication and promotes genetic instability' EJC Supplements, vol. 8, no. 5, 132, pp. 35-35.
https://doi.org/10.1016/S1359-6349(10)70940-X

Research output: Contribution To Journal



Khoury, MP & Bourdon, J-C 2010,

'The isoforms of the p53 protein' Cold spring harbor perspectives in biology, vol. 2, no. 3, a000927, pp. -.
https://doi.org/10.1101/cshperspect.a000927

Research output: Contribution To Journal



Baker, L, Quinlan, PR, Patten, N, Ashfield, A, Birse-Stewart-Bell, L-J, Mc Cowan, C, Bourdon, J-C, Purdie, CA, Jordan, LB, Dewar, JA, Wu, L & Thompson, AM 2010,

'p53 mutation, deprivation and poor prognosis in primary breast cancer' British Journal of Cancer, vol. 102, no. 4, pp. 719-726.
https://doi.org/10.1038/sj.bjc.6605540

Research output: Contribution To Journal



Machado-Silva, A, Perrier, S & Bourdon, J-C 2010,

'p53 family members in cancer diagnosis and treatment' Seminars in Cancer Biology, vol. 20, no. 1, pp. 57-62.
https://doi.org/10.1016/j.semcancer.2010.02.005

Research output: Contribution To Journal



Aoubala, M, Murray-Zmijewski, F, Khoury, M, Perrier, S, Fernandes, K, Prats, AC, Lane, D & Bourdon, JC 2010,

'D133P53, directly transactivated by p53, prevents p53-mediated apoptosis without inhibiting p53-mediated cell cycle arrest' Breast Cancer Research, vol. 12, P8, pp. S4-S4.
https://doi.org/10.1186/bcr2505

Research output: Contribution To Journal



Fujita, K, Mondal, AM, Horikawa, I, Nguyen, GH, Kumamoto, K, Sohn, JJ, Bowman, ED, Mathe, EA, Schetter, AJ, Pine, SR, Ji, H, Vojtesek, B, Bourdon, J-C, Lane, DP & Harris, CC 2009,

'p53 isoforms Delta 133p53 and p53 beta are endogenous regulators of replicative cellular senescence' Nature Cell Biology, vol. 11, no. 9, pp. 1135-U208.
https://doi.org/10.1038/ncb1928

Research output: Contribution To Journal



Chen, J, Ng, SM, Chang, C, Zhang, Z, Bourdon, J-C, Lane, DP & Peng, J 2009,

'p53 isoform Delta 113p53 is a p53 target gene that antagonizes p53 apoptotic activity via Bclx L activation in zebrafish' Genes & Development, vol. 23, no. 3, pp. 278-290.
https://doi.org/10.1101/gad.1761609

Research output: Contribution To Journal



Bergoglio, V, Lemee, F, Machado-Silva, A, Pillaire, MJ, Gentil, C, Baker, L, Martin, AL, Leduc, C, Lam, E, Magdeleine, E, Filleron, T, Thompson, A, Jordan, B, Spielman, M, Delozier, T, Fumoleau, P, Kaina, B, Seki, M, Wood, RD, Lacroix-Triki, M, Roche, H, Bourdon, J-C, Hoffmann, JS & Cazaux, C 2009,

'Gene expression of 3R in breast tumors from the CAPS01 protocol' Bulletin du Cancer, vol. 96, pp. S32-S33.

Research output: Contribution To Journal



Vendrell, JA, Bourdon, J, Cohen, PA & Thompson, AM 2009,

'Estrogen regulation of p53 isoforms in the human breast cancer cell line MCF7' Cancer Research, vol. 69, no. 2 Suppl. 1, 4067.
https://doi.org/10.1158/0008-5472.SABCS-4067

Research output: Contribution To Journal



Zocchi, L, Bourdon, JC, Codispoti, A, Knight, R, Lane, DP, Melino, G & Terrinoni, A 2008,

'Scotin: A new p63 target gene expressed during epidermal differentiation' Biochemical and Biophysical Research Communications, vol. 367, no. 2, pp. 271-276.
https://doi.org/10.1016/j.bbrc.2007.12.115

Research output: Contribution To Journal



Ebrahimi, M, Boldrup, L, Coates, PJ, Wahlin, Y-B, Bourdon, J-C & Nylander, K 2008,

'Expression of novel p53 isoforms in oral lichen planus' Oral Oncology, vol. 44, no. 2, pp. 156-161.
https://doi.org/10.1016/j.oraloncology.2007.01.014

Research output: Contribution To Journal



Dalvai, M, Dozier, C, Bourdon, JC & Ducommun, B 2008,

'Regulation of CDC25B expression by p53. An additional complexity step' Bulletin du Cancer, vol. 95, pp. S45 .

Research output: Contribution To Journal



Fernandes, K & Bourdon, JC 2008,

'p53 beta isoform modulates differentially p53 transcriptional activity in response to stress' Breast Cancer Research, vol. 10, pp. S9-S9.
https://doi.org/10.1186/bcr1896

Research output: Contribution To Journal



Draeby, I, Woods, YL, la Cour, JM, Mollerup, J, Bourdon, J-C & Berchtold, MW 2007,

'The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane' Archives of Biochemistry and Biophysics, vol. 467, no. 1, pp. 87-94.
https://doi.org/10.1016/j.abb.2007.07.028

Research output: Contribution To Journal



Bourdon, J-C 2007,

'p53 and its isoforms in cancer' British Journal of Cancer, vol. 97, no. 3, pp. 277-282.
https://doi.org/10.1038/sj.bjc.6603886

Research output: Contribution To Journal



Bourdon, J-C 2007,

'p53 family isoforms' Current Pharmaceutical Biotechnology, vol. 8, no. 6, pp. 332-336.

Research output: Contribution To Journal



Boldrup, L, Bourdon, J-C, Coates, PJ, Sjostrom, B & Nylander, K 2007,

'Expression of p53 isoforms in squamous cell carcinoma of the head and neck' European Journal of Cancer, vol. 43, no. 3, pp. 617-623.
https://doi.org/10.1016/j.ejca.2006.10.019

Research output: Contribution To Journal



Anensen, N, Oyan, AM, Bourdon, J-C, Kalland, KH, Bruserud, O & Gjertsen, BT 2006,

'A distinct p53 protein isoform signature reflects the onset of induction chemotherapy for acute myeloid leukemia' Clinical Cancer Research, vol. 12, no. 13, pp. 3985-3992.
https://doi.org/10.1158/1078-0432.CCR-05-1970

Research output: Contribution To Journal



Murray-Zmijewski, F, Lane, D & Bourdon, J-C 2006,

'p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress' Cell Death & Differentiation, vol. 13, no. 6, pp. 962-972.
https://doi.org/10.1038/sj.cdd.4401914

Research output: Contribution To Journal



Dudgeon, C, Kek, C, Demidov, ON, Saito, S, Fernandes, K, Diot, A, Bourdon, J-C, Lane, DP, Appella, E, Fornace , AJ & Bulavin, DV 2006,

'Tumor susceptibility and apoptosis defect in a mouse strain expressing a human p53 transgene' Cancer Research, vol. 66, no. 6, pp. 2928-2936.
https://doi.org/10.1158/0008-5472.CAN-05-2063

Research output: Contribution To Journal



Bourdon, JC, Fernandes, K, Murray-Zmijewski, F, Liu, G, Diot, A, Xirodimas, DP, Saville, MK & Lane, DP 2005,

'p53 isoforms can regulate p53 transcriptional activity' Genes & Development, vol. 19, no. 18, pp. 2122-2137.
https://doi.org/10.1101/gad.1339905

Research output: Contribution To Journal



Bates, GJ, Nicol, SM, Wilson, BJ, Jacobs, A-MF, Bourdon, J-C, Wardrop, J, Gregory, DJ, Lane, DP, Perkins, ND & Fuller-Pace, FV 2005,

'The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor' The EMBO Journal, vol. 24, no. 3, pp. 543-553.
https://doi.org/10.1038/sj.emboj.7600550

Research output: Contribution To Journal



Saville, MK, Sparks, A, Xirodimas, DP, Wardrop, J, Stevenson, LF, Bourdon, J-C, Woods, YL & Lane, DP 2004,

'Regulation of p53 by the ubiquitin-conjugating enzymes Ubc H5B/C in vivo' Journal of Biological Chemistry, vol. 279, no. 40, pp. 42169-42181.
https://doi.org/10.1074/jbc.M403362200

Research output: Contribution To Journal



Xirodimas, DP, Saville, MK, Bourdon, JC, Hay, RT & Lane, DP 2004,

'Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity' Cell, vol. 118, no. 1, pp. 83-97.
https://doi.org/10.1016/j.cell.2004.06.016

Research output: Contribution To Journal



Nagy, N, Takahara, M, Nishikawa, J, Bourdon, JC, Kis, LL, Klein, G & Klein, E 2004,

'Wild-type p53 activates SAP expression in lymphoid cells' Oncogene, vol. 23, no. 53, pp. 8563-8570.
https://doi.org/10.1038/sj.onc.1207908

Research output: Contribution To Journal



Paitel, E, Sunyach, C, da Costa, CA, Bourdon, J-C, Vincent, B & Checler, F 2004,

'Primary cultured neurons devoid of cellular prion display lower responsiveness to Staurosporine through the control of p53 at both transcriptional and post-transcriptional levels' Journal of Biological Chemistry, vol. 279, no. 1, pp. 612-618.
https://doi.org/10.1074/jbc.M310453200

Research output: Contribution To Journal



Tullo, A, Mastropasqua, G, Bourdon, JC, Centonze, P, Gostissa, M, Costanzo, A, Levrero, M, Del Sal, G, Saccone, C & Sbisa, E 2003,

'Adenosine deaminase, a key enzyme in DNA precursors control, is a new p73 target' Oncogene, vol. 22, no. 54, pp. 8738-8748.
https://doi.org/10.1038/sj.onc.1206967

Research output: Contribution To Journal



Bourdon, JC, De Laurenzi, V, Melino, G & Lane, D 2003,

'p53: 25 years of research and more questions to answer' Cell Death & Differentiation, vol. 10, no. 4, pp. 397-399.
https://doi.org/10.1038/sj.cdd.4401243

Research output: Contribution To Journal



Bourdon, J-C, Renzing, J, Robertson, PL, Fernandes, KN & Lane, DP 2002,

'Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane' Journal of Cell Biology, vol. 158, no. 2, pp. 235-246.
https://doi.org/10.1083/jcb.200203006

Research output: Contribution To Journal



Deguin-Chambon, V, Vacher, M, Jullien, M, May, E & Bourdon, J-C 2000,

'Direct transactivation of c-Ha-Ras gene by p53: evidence for its involvement in p53 transactivation activity and p53-mediated apoptosis' Oncogene, vol. 19, no. 51, pp. 5831-5841.

Research output: Contribution To Journal



Munsch, D, Watanabe-Fukunaga, R, Bourdon, J-C, Nagata, S, May, E, Yonish-Rouach, E & Reisdorf, P 2000,

'Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis' Journal of Biological Chemistry, vol. 275, no. 6, pp. 3867-3872.
https://doi.org/10.1074/jbc.275.6.3867

Research output: Contribution To Journal



Nylander, K, Bourdon, J-C, Bray, SE, Gibbs, NK, Kay, R, Hart, I & Hall, PA 2000,

'Transcriptional activation of tyrosinase and TRP-I by p53 links UV irradiation to the protective tanning response' Journal of Pathology, vol. 190, no. 1, pp. 39-46.
https://doi.org/10.1002/(SICI)1096-9896(200001)190:1<39::AID-PATH492>3.0.CO;2-V

Research output: Contribution To Journal



Miro, F, Lelong, J-C, Pancetti, F, Roher, N, Duthu, A, Plana, M, Bourdon, JC, Bachs, O, May, E & Itarte, E 1999,

'Tumour suppressor protein p53 released by nuclease digestion increases at the onset of rat liver regeneration' Journal of Hepatology, vol. 31, no. 2, pp. 306-314.

Research output: Contribution To Journal



Bourdon, J-C, Deguin-Chambon, V, Lelong, J-C, Dessen, P, May, P, Debuire, B & May, E 1997,

'Further characterisation of the p53 responsive element - identification of new candidate genes for trans-activation by p53' Oncogene, vol. 14, no. 1, pp. 85-94.

Research output: Contribution To Journal



Bourdon, J-C, D'Errico, A, Paterlini, P, Grigioni, W, May, E & Debuire, B 1995,

'p53 protein accumulation in European hepatocellular carcinoma is not always dependent on p53 gene mutation' Gastroenterology, vol. 108, no. 4, pp. 1176-1182.
https://doi.org/10.1016/0016-5085(95)90217-1

Research output: Contribution To Journal



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