Isla Mackenzie

+44 (0)1382 383119
Professor of Cardiovascular Medicine & Honorary Consultant Physician

Bio

Biography

Dr Isla Mackenzie MBChB (Honours), PhD, FRCP Edin, FBPharmacolS is a Clinical Reader in Clinical Pharmacology and Honorary Consultant Physician at the University of Dundee and Ninewells Hospital, Dundee.  Research interests include cardiovascular safety of drugs, clinical trials, hypertension and technology in research.

Clinical interests include general medicine, hypertension and adrenal disorders including phaeochromocytoma. Dr Mackenzie trained in Clinical Pharmacology in Cambridge prior to moving to Dundee in 2008.

Publications

Pigazzani, F, Mackenzie, I & Mac Donald, TM 2018,

'Ibuprofen and Paracetamol: Acceptably Safe for All?' Drug Safety, vol. 41, no. 11, pp. 99-101.
https://doi.org/10.1007/s40264-018-0717-4

Research output: Contribution To Journal



Mac Donald, TM & Mackenzie, IS 2018,

'Reaching an ACCORD on Glycemia and Systolic Blood Pressure Targets in Type 2 Diabetes Mellitus' Journal of the American Heart Association, vol. 7, no. 18, e010508, pp. e010508.
https://doi.org/10.1161/JAHA.118.010508

Research output: Contribution To Journal



Rogers, A, Morrison, I, Rorie, D, Mackenzie, I & Mac Donald, T 2018,

'Protocol for Assessment of Sleep Quality and Duration in the Treatment In Morning versus Evening (TIME) study: a randomised controlled trial using online Patient Reported Outcome Measures' BMJ Open, vol. 8, no. 6, e21890, pp. 1-6.
https://doi.org/10.1136/bmjopen-2018-021890

Research output: Contribution To Journal



Williams, B, Mac Donald, TM, Morant, SV, Webb, DJ, Sever, P, Mc Innes, GT, Ford, I, Cruickshank, JK, Caulfield, MJ, Padmanabhan, S, Mackenzie, IS & Salsbury, J & Brown, MJ 2018,

'Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies' The Lancet Diabetes and Endocrinology, vol. 6, no. 6, pp. 464-475.
https://doi.org/10.1016/S2213-8587(18)30071-8

Research output: Contribution To Journal



Rorie, DA, Flynn, RWV, Mackenzie, IS, Mac Donald, TM & Rogers, A 2017,

'The Treatment In Morning versus Evening (TIME) study: Analysis of recruitment, follow-up and retention rates post-recruitment' Trials, vol. 18, 557, pp. 1-8.
https://doi.org/10.1186/s13063-017-2318-4

Research output: Contribution To Journal



Mac Donald, TM, Williams, B, Webb, DJ, Morant, S, Caulfield, M, Cruickshank, JK, Ford, I, Sever, P, Mackenzie, IS, Padmanabhan, S, Mc Cann, GP, Salsbury, J, Mc Innes, G, Brown, MJ & for The British Hypertension Society Programme of Prevention And Treatment of Hypertension With Algorithm‐based Therapy (PATHWAY) 2017,

'Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double-Blind Randomized Controlled Trial' Journal of the American Heart Association, vol. 6, no. 11, e006986, pp. 1-28.
https://doi.org/10.1161/JAHA.117.006986

Research output: Contribution To Journal



Rorie, DA, Flynn, RWV, Grieve, K, Doney, A, Mackenzie, I, Mac Donald, TM & Rogers, A 2017,

'Electronic case report forms and electronic data capture within clinical trials and pharmacoepidemiology' British Journal of Clinical Pharmacology, vol. 83, no. 9, pp. 1880-1895.
https://doi.org/10.1111/bcp.13285

Research output: Contribution To Journal



Mac Donald, T, Hawkey, CJ, Ford, I, Mc Murray, JJV, Scheiman, JM, Hallas, J, Findlay, E, Grobbee, DE, Hobbs, FDR, Ralston, SH, Reid, DM, Walters, M, Webster, J, Ruschitzka, F, Ritchie, LD, Perez-Gutthann, S, Connolly, E, Greenlaw, N, Wilson, A, Wei, L & Mackenzie, I 2017,

'Randomised trial of switching from prescribed non-selective non-steroidal anti-inflammatory drugs to prescribed celecoxib: The Standard care versus Celecoxib Outcome Trial (SCOT)' European Heart Journal, vol. 38, no. 23, pp. 1843-1850.
https://doi.org/10.1093/eurheartj/ehw387

Research output: Contribution To Journal



Wei, L, Ratnayake, L, Phillips, G, Mc Guigan, CC, Morant, SV, Flynn, RW, Mackenzie, IS & Mac Donald, TM 2017,

'Acid-suppression medications and bacterial gastroenteritis: a population-based cohort study' British Journal of Clinical Pharmacology, vol. 83, no. 6, pp. 1298-1308.
https://doi.org/10.1111/bcp.13205

Research output: Contribution To Journal



Rogers, A, Mackenzie, I, Rorie, D & Mac Donald, T 2017,

Successful recruitment to a large online randomised trial: the TIME study. in Trials: Meeting abstracts from the 4th International Clinical Trials Methodology Conference (ICTMC) and the 38th Annual Meeting of the Society for Clinical Trials. Supplement 1 edn, vol. 18, 089, Trials, no. Suppl. 1, vol. 18, Bio Med Central, United Kingdom, pp. 222-223.
https://doi.org/10.1186/s13063-017-1902-y

Research output: Contribution To Book Anthology



Mackenzie, IS, Morant, SV, Wei, L, Thompson, AM & Mac Donald, TM 2017,

'Spironolactone use and risk of incident cancers: a retrospective, matched cohort study' British Journal of Clinical Pharmacology, vol. 83, no. 3, pp. 653-663.
https://doi.org/10.1111/bcp.13152

Research output: Contribution To Journal



Rogers, A, Flynn, RWV, Mc Donnell, P, Mackenzie, IS & Macdonald, TM 2016,

'A novel drug management system in the Febuxostat versus Allopurinol Streamlined Trial: A description of a pharmacy system designed to supply medications directly to patients within a prospective multicenter randomised clinical trial' Clinical Trials, vol. 13, no. 6, pp. 665-670.
https://doi.org/10.1177/1740774516657048

Research output: Contribution To Journal



Mackenzie, IS, Ford, I, Walker, A, Hawkey, C, Begg, A, Avery, A, Taggar, J, Wei, L, Struthers, AD, Mac Donald, TM & ALL-HEART study group 2016,

'Multicentre, prospective, randomised, open-label, blinded end point trial of the efficacy of allopurinol therapy in improving cardiovascular outcomes in patients with ischaemic heart disease: protocol of the ALL-HEART study' BMJ Open, vol. 6, no. 9, e013774, pp. 1-9.
https://doi.org/10.1136/bmjopen-2016-013774

Research output: Contribution To Journal



Rorie, DA, Rogers, A, Mackenzie, IS, Ford, I, Webb, DJ, Willams, B, Brown, M, Poulter, N, Findlay, E, Saywood, W & Mac Donald, TM 2016,

'Methods of a large prospective, randomised, open-label, blinded end-point study comparing morning versus evening dosing in hypertensive patients: the Treatment In Morning versus Evening (TIME) study' BMJ Open, vol. 6, no. 2, e010313.
https://doi.org/10.1136/bmjopen-2015-010313

Research output: Contribution To Journal



Brown, MJ, Williams, B, Morant, SV, Webb, DJ, Caulfield, MJ, Cruickshank, JK, Ford, I, Mc Innes, G, Sever, P, Salsbury, J, Mackenzie, IS, Padmanabhan, S, Mac Donald, TM & for the British Hypertension Society's Prevention, Treatment of Hypertension with Algorithm-based Therapy (PATHWAY) Studies Group 2016,

'Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial' The Lancet: Diabetes and Endocrinology, vol. 4, no. 2, pp. 136-147.
https://doi.org/10.1016/S2213-8587(15)00377-0

Research output: Contribution To Journal



Williams, B, Mac Donald, TM, Morant, S, Webb, DJ, Sever, P, Mc Innes, G, Ford, I, Cruickshank, JK, Caulfield, MJ, Salsbury, J, Mackenzie, I, Padmanabhan, S, Brown, MJ & or The British Hypertension Society's PATHWAY Studies Group 2015,

'Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial' Lancet, vol. 386, no. 10008, pp. 2059-2068.
https://doi.org/10.1016/S0140-6736(15)00257-3

Research output: Contribution To Journal



Tzemos, N, Lim, PO, Mackenzie, IS & Macdonald, TM 2015,

'Exaggerated exercise blood pressure response and future cardiovascular disease' Journal of Clinical Hypertension , vol. 17, no. 11, pp. 837-844.
https://doi.org/10.1111/jch.12629

Research output: Contribution To Journal



Mac Donald, TM, Williams, B, Caulfield, M, Cruickshank, JK, Mc Innes, G, Sever, P, Webb, DJ, Mackenzie, IS, Salsbury, J, Morant, S, Ford, I & Brown, MJ 2015,

'Monotherapy versus dual therapy for the initial treatment of hypertension (PATHWAY-1): a randomised double-blind controlled trial' BMJ Open, vol. 5, no. 8, e007645.
https://doi.org/10.1136/bmjopen-2015-007645

Research output: Contribution To Journal



Rorie, D, Flynn, R, Mc Connachie, L, Mackenzie, IS & Mac Donald, TM 2015,

'Poster advertisements in practice waiting rooms to recruit patients to the Treatment In Morning vs. Evening (TIME) online study' British Journal of Clinical Pharmacology, vol. 80, no. 2, pp. 325-326.
https://doi.org/10.1111/bcp.12609

Research output: Contribution To Journal



Jennings, CG, Mac Donald, TM, Wei, L, Brown, MJ, Mc Connachie, L & Mackenzie, IS 2015,

'Does offering an incentive payment improve recruitment to clinical trials and increase the proportion of socially deprived and elderly participants?' Trials, vol. 16, 80.
https://doi.org/10.1186/s13063-015-0582-8

Research output: Contribution To Journal



Wei, L, Mackenzie, IS, Mac Donald, TM & George, J 2014,

'Cardiovascular risk associated with sodium-containing medicines' Expert Opinion on Drug Safety, vol. 13, no. 11, pp. 1515-1523.
https://doi.org/10.1517/14740338.2014.970163

Research output: Contribution To Journal



Flynn, RW, Mac Donald, TM, Hapca, A, Mac Kenzie, IS & Schembri, S 2014,

'Quantifying the real life risk profile of inhaled corticosteroids in COPD by record linkage analysis' Respiratory Research, vol. 15, 141.
https://doi.org/10.1186/s12931-014-0141-y

Research output: Contribution To Journal



Jennings, CG, Mackenzie, IS, Flynn, R, Ford, I, Nuki, G, De Caterina, R, Riches, PL, Ralston, SH, Mac Donald, TM & FAST study group 2014,

'Up-titration of allopurinol in patients with gout' Seminars in Arthritis and Rheumatism, vol. 44, no. 1, pp. 25-30.
https://doi.org/10.1016/j.semarthrit.2014.01.004

Research output: Contribution To Journal



Mac Donald, TM, Ford, I, Nuki, G, Mackenzie, IS, De Caterina, R, Findlay, E, Hallas, J, Hawkey, CJ, Ralston, S, Walters, M, Webster, J, Mc Murray, J, Perez Ruiz, F & Jennings, CG 2014,

'Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST): a large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia' BMJ Open, vol. 4, no. 7, e005354.
https://doi.org/10.1136/bmjopen-2014-005354

Research output: Contribution To Journal



Hapca, A, Jennings, CG, Wei, L, Wilson, A, Mac Donald, TM & Mackenzie, IS 2014,

'Effectiveness of newspaper advertising for patient recruitment into a clinical trial' British Journal of Clinical Pharmacology, vol. 77, no. 6, pp. 1064-1072.
https://doi.org/10.1111/bcp.12262

Research output: Contribution To Journal



Jennings, CG, Houston, JG, Severn, A, Bell, S, Mackenzie, IS & Mac Donald, TM 2014,

'Renal artery stenosis-when to screen, what to stent?' Current Atherosclerosis Reports, vol. 16, no. 6, 416.
https://doi.org/10.1007/s11883-014-0416-2

Research output: Contribution To Journal



Witham, MD, Ireland, S, Houston, JG, Gandy, SJ, Waugh, S, Mac Donald, TM, Mackenzie, IS & Struthers, AD 2014,

'Vitamin D therapy to reduce blood pressure and left ventricular hypertrophy in resistant hypertension: randomized, controlled trial' Hypertension, vol. 63, no. 4, pp. 706-712.
https://doi.org/10.1161/HYPERTENSIONAHA.113.02177

Research output: Contribution To Journal



Mackenzie, IS, Morant, SV, Bloomfield, GA, Mac Donald, TM & O'Riordan, J 2014,

'Incidence and prevalence of multiple sclerosis in the UK 1990-2010: a descriptive study in the General Practice Research Database' Journal of Neurology, Neurosurgery & Psychiatry, vol. 85, no. 1, pp. 76-84.
https://doi.org/10.1136/jnnp-2013-305450

Research output: Contribution To Journal



George, J, Majeed, W, Mackenzie, IS, Mac Donald, TM & Wei, L 2013,

'Association between cardiovascular events and sodium-containing effervescent, dispersible, and soluble drugs: nested case-control study' BMJ, vol. 347, f6954.
https://doi.org/10.1136/bmj.f6954

Research output: Contribution To Journal



Mackenzie, IS, Morant, SV, Bloomfield, GA, Macdonald, TM & O'Riordan, JI 2013,

'Changing face of multiple sclerosis in the United kingdom 1990-2010: an incidence and prevalence study' Journal of Neurology, Neurosurgery and Psychiatry, vol. 84, no. 11, ABN Abstracts 027.
https://doi.org/10.1136/jnnp-2013-306573.27

Research output: Contribution To Journal



Wei, L, Macdonald, TM & Mackenzie, IS 2013,

'Pioglitazone and bladder cancer: A propensity score matched cohort study' British Journal of Clinical Pharmacology, vol. 75, no. 1, pp. 254-259.
https://doi.org/10.1111/j.1365-2125.2012.04325.x

Research output: Contribution To Journal



Mackenzie, IS, Wei, L & Mac Donald, TM 2013,

'Cardiovascular safety of lumiracoxib: a meta-analysis of randomised controlled trials in patients with osteoarthritis' European Journal of Clinical Pharmacology, vol. 69, no. 2, pp. 133-141.
https://doi.org/10.1007/s00228-012-1335-1

Research output: Contribution To Journal



Mac Donald, TM, Mackenzie, IS, Wei, L, Hawkey, CJ & Ford, I 2013,

'Methodology of a large prospective, randomised, open, blinded endpoint streamlined safety study of celecoxib versus traditional non-steroidal anti-inflammatory drugs in patients with osteoarthritis or rheumatoid arthritis: protocol of the standard care versus celecoxib outcome trial (SCOT)' BMJ Open, vol. 3, no. 1, e002295.
https://doi.org/10.1136/bmjopen-2012-002295

Research output: Contribution To Journal



Mackenzie, IS, Mac Donald, TM, Thompson, AM, Morant, S & Wei, L 2012,

'Spironolactone and the risk of breast cancer: a cohort study' Pharmacoepidemiology and Drug Safety, vol. 21, no. Supplement s3, 550, pp. 258-258.
https://doi.org/10.1002/pds.3324

Research output: Contribution To Journal



Flynn, RW, Mc Donnell, PG, Mackenzie, IS, Wei, L & Mac Donald, TM 2012,

'An efficient and inexpensive system for the distribution and tracking of investigational medicinal products in streamlined safety trials' Pharmacoepidemiology and Drug Safety, vol. 21, no. Supplement s3, 263, pp. 124-124.
https://doi.org/10.1002/pds.3324

Research output: Contribution To Journal



Wei, L, Hapca, A, Mackenzie, IS & Mac Donald, TM 2012,

'Media campaign for recruitment to a streamlined safety trial in Scotland' Pharmacoepidemiology and Drug Safety, vol. 21, no. Supplement s3, 272, pp. 128-128.
https://doi.org/10.1002/pds.3324

Research output: Contribution To Journal



Wei, L, Mac Donald, TM, Flynn, RW, Wilson, A & Mackenzie, IS 2012,

'Variations in recruitment rate in a multicentre streamlined safety trial' Pharmacoepidemiology and Drug Safety, vol. 21, no. Supplement s3, 184, pp. 87-87.
https://doi.org/10.1002/pds.3324

Research output: Contribution To Journal



Flynn, RW, Saywood, W, Mackenzie, IS, Wei, L & Mac Donald, TM 2012,

'A pilot study to investigate the supply of investigational medicinal product to patients via mail in a streamlined safety study' Pharmacoepidemiology and Drug Safety, vol. 21, no. Supplement S3, 264, pp. 124-125.
https://doi.org/10.1002/pds.3324

Research output: Contribution To Journal



Burton, TJ, Mackenzie, IS, Balan, K, Koo, B, Bird, N, Soloviev, DV, Azizan, EAB, Aigbirhio, F, Gurnell, M & Brown, MJ 2012,

'Evaluation of the sensitivity and specificity of (11)C-metomidate positron emission tomography (PET)-CT for lateralizing aldosterone secretion by Conn's adenomas' Journal of Clinical Endocrinology & Metabolism, vol. 97, no. 1, pp. 100-9.
https://doi.org/10.1210/jc.2011-1537

Research output: Contribution To Journal



Mackenzie, IS, Macdonald, TM, Shakir, S, Dryburgh, M, Mantay, BJ, Mc Donnell, P & Layton, D 2012,

'Influenza H1N1 (swine flu) vaccination: a safety surveillance feasibility study using self-reporting of serious adverse events and pregnancy outcomes' British Journal of Clinical Pharmacology, vol. 73, no. 5, pp. 801-811.
https://doi.org/10.1111/j.1365-2125.2011.04142.x

Research output: Contribution To Journal



Mackenzie, IS, Macdonald, TM, Thompson, A, Morant, S & Wei, L 2012,

'Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study' British Medical Journal, vol. 345, e4447, pp. e4447.
https://doi.org/10.1136/bmj.e4447

Research output: Contribution To Journal



Mac Kenzie, IS, Wei, L, Paterson, KR & Mac Donald, TM 2012,

'Cluster randomized trials of prescription medicines or prescribing policy: public and general practitioner opinions in Scotland' British Journal of Clinical Pharmacology, vol. 74, no. 2, pp. 354-361.
https://doi.org/10.1111/j.1365-2125.2012.04195.x

Research output: Contribution To Journal



Wei, L, Mac Donald, TM & Mackenzie, IS 2011,

'Co-prescription of co-trimoxazole and spironolactone in elderly patients' BMJ, vol. 343, no. 7823, d5656, pp. -.
https://doi.org/10.1136/bmj.d5656

Research output: Contribution To Journal



Mackenzie, IS, Mantay, BJ, Mc Donnell, PG, Wei, L & Mac Donald, TM 2011,

'Managing security and privacy concerns over data storage in healthcare research' Pharmacoepidemiology and Drug Safety, vol. 20, no. 8, pp. 885-893.
https://doi.org/10.1002/pds.2170

Research output: Contribution To Journal



Mackenzie, IS, Mantay, BJ, Mc Donnell, PG, Wei, L & Mac Donald, TM 2011,

'Managing Security and Privacy Concerns over Data Storage in Healthcare Research' Pharmacoepidemiology and Drug Safety, vol. 20, no. s1, pp. S170-S170.
https://doi.org/10.1002/pds.2206

Research output: Contribution To Journal



Mackenzie, IS, Wei, L & Mac Donald, TM 2011,

'Changing Practice Formularies To Study the Comparative Safety and Effectiveness of Medicines: A Concept That Is Supported by the Public' Pharmacoepidemiology and Drug Safety, vol. 20, no. s1, pp. S217-S217.
https://doi.org/10.1002/pds.2206

Research output: Contribution To Journal



Mackenzie, IS, Wei, L, Paterson, K & Mac Donald, TM 2011,

'Randomized Policy Trials: A Powerful Tool for Drug Safety and Effectiveness' Pharmacoepidemiology and Drug Safety, vol. 20, no. s1, pp. S313-S313.
https://doi.org/10.1002/pds.2206

Research output: Contribution To Journal



Mackenzie, IS, Wei, L & Mac Donald, TM 2011,

'Cardiovascular Safety of Lumiracoxib: A Meta-Analysis of Randomised Controlled Trials in Patients with Osteoarthritis' Pharmacoepidemiology and Drug Safety, vol. 20, no. s1, pp. S354-S354.
https://doi.org/10.1002/pds.2206

Research output: Contribution To Journal



Layton, D, Dryburgh, M, Mantay, B, Mac Donald, TM, Shakir, SAW & Mac Kenzie, IS 2011,

'Pilot Swine Flu Vaccination Active Surveillance Study: Final Results' Pharmacoepidemiology and Drug Safety, vol. 20, pp. S86-S87.
https://doi.org/10.1002/pds.2206

Research output: Contribution To Journal



Mackenzie, IS, Mantay, BJ, Mc Donnell, PG, Wei, L & Mac Donald, TM 2011,

'Managing security and privacy concerns over data storage in healthcare research' Pharmacoepidemiology and Drug Safety, vol. 20, no. 8, pp. 885-893.
https://doi.org/10.1002/pds.2170

Research output: Contribution To Journal



Wei, L, Mackenzie, IS, Chen, Y, Struthers, AD & Mac Donald, TM 2011,

'Impact of allopurinol use on urate concentration and cardiovascular outcome' British Journal of Clinical Pharmacology, vol. 71, no. 4, pp. 600-7.
https://doi.org/10.1111/j.1365-2125.2010.03887.x

Research output: Contribution To Journal



Mackenzie, IS & Mac Donald, TM 2011,

'Hypertension in octogenarians: treatment strategies and challenges' European Cardiology, vol. 7, no. 1, pp. 25-28.

Research output: Contribution To Journal



Layton, D, Dryburgh, M, Mac Donald, TM, Shakir, SA & Mackenzie, IS 2011,

'Pilot Swine Flu Vaccination Active Surveillance Study: Final Results' Drug Safety, vol. 34, no. 10, pp. 889-890.
https://doi.org/10.2165/11596230-000000000-00000

Research output: Contribution To Journal



Mackenzie, IS, Coughtrie, MWH, Mac Donald, TM & Wei, L 2010,

'Antiplatelet drug interactions' Journal of General Internal Medicine, vol. 268, no. 6, pp. 516-529.
https://doi.org/10.1111/j.1365-2796.2010.02299.x

Research output: Contribution To Journal



Mackenzie, IS, Wei, L, Rutherford, D, Findlay, EA, Saywood, W, Campbell, MK & Mac Donald, TM 2010,

'Promoting public awareness of randomised clinical trials using the media: the 'Get Randomised' campaign' British Journal of Clinical Pharmacology, vol. 69, no. 2, pp. 128-135.
https://doi.org/10.1111/j.1365-2125.2009.03561.x

Research output: Contribution To Journal



Mackenzie, IS & Mac Donald, TM 2010,

'Treatment of osteoarthritis in hypertensive patients' Expert Opinion on Pharmacotherapy, vol. 11, no. 3, pp. 393-403.
https://doi.org/10.1517/14656560903496422

Research output: Contribution To Journal



Wei, L, Mackenzie, IS, Chen, Y, Struthers, AD & Mac Donald, TM 2010,

'Impact of allopurinol use on urate concentration and cardiovascular outcome' European Heart Journal, vol. 31, no. s1, P4700, pp. 812-813.

Research output: Contribution To Journal



Layton, D, Rutherford, D, Mac Donald, TM, Shakir, S & Mackenzie, IS 2010,

'Pilot Swine Flu Vaccination Active Surveillance Study: Design and Rationale' Drug Safety, vol. 33, no. 10, pp. 898-898.
https://doi.org/10.2165/11532470-000000000-00000

Research output: Contribution To Journal



Layton, D, Rutherford, D, Mac Donald, TM, Shakir, S & Mackenzie, IS 2010,

'Pilot Swine Flu Vaccination Active Surveillance Study: Interim Results' Drug Safety, vol. 33, no. 10, pp. 898-899.
https://doi.org/10.2165/11532470-000000000-00000

Research output: Contribution To Journal



Mackenzie, IS, Dryburgh, M, Rutherford, D, Mac Donald, TM, Shakir, S & Layton, D 2010,

'Participation of General Practices in a Swine Flu Vaccination Study' Drug Safety, vol. 33, no. 10, pp. 911-911.

Research output: Contribution To Journal



Cheriyan, J, Burton, TJ, Bradley, TJ, Wallace, SML, Mäki-Petäjä, KM, Mac Kenzie, IS, Mc Eniery, CM, Brown, J & Wilkinson, IB 2009,

'The effects of urotensin II and urantide on forearm blood flow and systemic haemodynamics in humans' British Journal of Clinical Pharmacology, vol. 68, no. 4, pp. 518-523.
https://doi.org/10.1111/j.1365-2125.2009.03475.x

Research output: Contribution To Journal



Mac Kenzie, IS 2009,

'European association for clinical pharmacology and therapeutics - 9th congress' IDrugs, vol. 12, no. 9, pp. 550-554.

Research output: Contribution To Journal



Mackenzie, IS, Rutherford, D, Findlay, E, Saywood, W, Campbell, MK & Mac Donald, TM 2009,

'The 'Get Randomised' campaign: promoting understanding of randomised clinical trials through the media' Basic & Clinical Pharmacology & Toxicology, vol. 105, pp. 24-24.

Research output: Contribution To Journal



Mackenzie, IS, Mc Eniery, CM, Dhakam, Z, Brown, MJ, Cockcroft, JR & Wilkinson, IB 2009,

'Comparison of the Effects of Antihypertensive Agents on Central Blood Pressure and Arterial Stiffness in Isolated Systolic Hypertension' Hypertension, vol. 54, no. 2, pp. 409-413.
https://doi.org/10.1161/HYPERTENSIONAHA.109.133801

Research output: Contribution To Journal



Mackenzie, IS & Brown, MJ 2009,

'Molecular and clinical investigations in patients with low-renin hypertension' Clinical and Experimental Nephrology, vol. 13, no. 1, pp. 18.
https://doi.org/10.1007/s10157-008-0071-4

Research output: Contribution To Journal



Mackenzie, IS, Rutherford, D & Mac Donald, TM 2008,

'Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis' Arthritis Research & Therapy, vol. 10, S3, pp. -.
https://doi.org/10.1186/ar2464

Research output: Contribution To Journal



Mackenzie, IS & Brown, MJ 2007,

'Pseudopheochromocytoma' Journal of Hypertension, vol. 25, no. 11, pp. 2204-2206.
https://doi.org/10.1097/HJH.0b013e3282f0fdbc

Research output: Contribution To Journal



Mackenzie, IS, Gurnell, M, Balan, KK, Simpson, H, Chatterjee, K & Brown, MJ 2007,

'The use of 18-fluoro-dihydroxyphenylalanine and 18-fluorodeoxyglucose positron emission tomography scanning in the assessment of metaiodobenzylguanidine-negative phaeochromocytoma' European Journal of Endocrinology, vol. 157, no. 4, pp. 533-537.
https://doi.org/10.1530/EJE-07-0369

Research output: Contribution To Journal



Brady, AJB, Mackenzie, IS, Ritchie, S & Brown, MJ 2007,

'Grand Rounds at the British Hypertension Society: Renal artery stenosis' Journal of Human Hypertension, vol. 21, no. 9, pp. 750-755.
https://doi.org/10.1038/sj.jhh.1002260

Research output: Contribution To Journal



Mc Eniery, CM, Wallace, S, Mac Kenzie, IS, Mc Donnell, B, Newby, DE, Cockcroft, JR & Wilkinson, IB 2006,

'Endothelial function is associated with pulse pressure, pulse wave velocity, and augmentation index in healthy humans' Hypertension, vol. 48, no. 4, pp. 602-608.
https://doi.org/10.1161/01.HYP.0000239206.64270.5f

Research output: Contribution To Journal



Brown, MJ, Mackenzie, IS, Ashby, MJ, Balan, KK & Appleton, DS 2006,

'AT2 receptor stimulation may halt progression of pheochromocytoma' Annals of the New York Academy of Sciences, vol. 1073, no. 1, pp. 436-443.
https://doi.org/10.1196/annals.1353.047

Research output: Contribution To Journal



Mackenzie, IS, Ashby, MJ, Donovan, T, Voutnis, DD & Brown, MJ 2006,

'Bilateral adrenal masses: Phaeochromocytoma or melanoma?' Journal of the Royal Society of Medicine, vol. 99, no. 3, pp. 153-155.
https://doi.org/10.1177/014107680609900319

Research output: Contribution To Journal



Mackenzie, IS, Maki-Petaja, KM, Mc Eniery, CM, Bao, YP, Wallace, SM, Cheriyan, J, Monteith, S, Brown, MJ & Wilkinson, IB 2005,

'Aldehyde dehydrogenase 2 plays a role in the bioactivation of nitroglycerin in humans' Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 25, no. 9, pp. 1891-1895.
https://doi.org/10.1161/01.ATV.0000179599.71086.89

Research output: Contribution To Journal



Yasmin, Mc Eniery, CM, Wallace, S, Mackenzie, IS, Cockcroft, JR & Wilkinson, IB 2004,

'C-Reactive Protein Is Associated with Arterial Stiffness in Apparently Healthy Individuals' Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 24, no. 5, pp. 969-974.
https://doi.org/10.1161/01.ATV.zhq0504.0173

Research output: Contribution To Journal



Booth, AD, Jayne, DRW, Kharbanda, RK, Mc Eniery, CM, Mackenzie, IS, Brown, J & Wilkinson, IB 2004,

'Infliximab Improves Endothelial Dysfunction in Systemic Vasculitis: A Model of Vascular Inflammation' Circulation, vol. 109, no. 14, pp. 1718-1723.
https://doi.org/10.1161/01.CIR.0000124720.18538.DD

Research output: Contribution To Journal



Mackenzie, IS & Brown, MJ 2002,

'Genetic profiling versus drug rotation in the optimisation of antihypertensive treatment' Clinical Medicine, vol. 2, no. 5, pp. 465-473.
https://doi.org/10.7861/clinmedicine.2-5-465

Research output: Contribution To Journal



Mackenzie, IS, Wilkinson, IB & Cockcroft, JR 2002,

'Assessment of arterial stiffness in clinical practice' QJM - Monthly Journal of the Association of Physicians, vol. 95, no. 2, pp. 67-74.
https://doi.org/10.1093/qjmed/95.2.67

Research output: Contribution To Journal



Wilkinson, IB, Hall, IR, Mac Callum, H, Mackenzie, IS, Mc Eniery, CM, Van der Arend, BJ, Shu, YE, Mac Kay, LS, Webb, DJ & Cockcroft, JR 2002,

'Pulse-wave analysis: Clinical evaluation of a noninvasive, widely applicable method for assessing endothelial function' Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 22, no. 1, pp. 147-152.
https://doi.org/10.1161/hq0102.101770

Research output: Contribution To Journal



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Activities

British Journal of Clinical Pharmacology (Journal)

Role: Editor
Activity: Editorial activity

1 1 2012

British Hypertension Society (External organisation)

Role: Member
Activity: Membership of committee

  2012