Douglas Steele

+44 (0)1382 496233
Deputy Head of Division - Imaging Science and Technology & Professor of Neuroimaging & Consultant Psychiatrist

Publications

Rupprechter, S, Stankevicius, A, Huys, QJM, Steele, J & Seriès, P 2018,

'Major Depression Impairs the Use of Reward Values for Decision-Making' Scientific Reports, vol. 8, 13798.
https://doi.org/10.1038/s41598-018-31730-w

Research output: Contribution To Journal



Emser, TS, Johnston, B, Steele, J, Kooij, S, Thorell, L & Christiansen, H 2018,

'Assessing ADHD symptoms in children and adults: Evaluating the role of objective measures using the Qbtest' Behavioral and Brain Functions, vol. 14, 11, pp. 1-14.
https://doi.org/10.1186/s12993-018-0143-x

Research output: Contribution To Journal



Tolomeo, S, Matthews, K, Steele, JD & Baldacchino, A 2018,

'Compulsivity in opioid dependence' Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 81, pp. 333-339.
https://doi.org/10.1016/j.pnpbp.2017.09.007

Research output: Contribution To Journal



Valton, V, Romaniuk, L, Steele, D, Lawrie, S & Series, P 2017,

'Comprehensive review: Computational modelling of Schizophrenia' Neuroscience and Biobehavioral Reviews, vol. 83, pp. 631-646.
https://doi.org/10.1016/j.neubiorev.2017.08.022

Research output: Contribution To Journal



Kumara, P, Waiter, GD, Dubois, M, Milders, M, Reid , I & Steele, JD 2017,

'Increased neural response to social rejection in major depression' Depression and Anxiety, vol. 34, no. 11, pp. 1049-1056.
https://doi.org/10.1002/da.22665

Research output: Contribution To Journal



Currie, J, Buruju, D, Perrin, JS, Reid, IC, Steele, JD & Feltovich, N 2017,

'Schizophrenia illness severity is associated with reduced loss aversion' Brain Research, vol. 1664, pp. 9-16.
https://doi.org/10.1016/j.brainres.2017.03.006

Research output: Contribution To Journal



Stolicyn, A, Steele, JD & Seriès, P 2017,

'Conditioned task-set competition: Neural mechanisms of emotional interference in depression' Cognitive, Affective, and Behavioral Neuroscience, vol. 17, no. 2, pp. 269-289.
https://doi.org/10.3758/s13415-016-0478-4

Research output: Contribution To Journal



Raymond, JG, Steele, JD & Seriès, P 2017,

'Modeling trait anxiety: from computational processes to personality' Frontiers in Psychiatry, vol. 8, 1, pp. 1-19.
https://doi.org/10.3389/fpsyt.2017.00001

Research output: Contribution To Journal



Romaniuk, L, Pope, M, Nicol, K, Steele, J & Hall, J 2016,

'Neural correlates of fears of abandonment and rejection in borderline personality disorder' Wellcome Open Research, vol. 1, no. 33, pp. 1-11.
https://doi.org/10.12688/wellcomeopenres.10331.1

Research output: Contribution To Journal



Tolomeo, S, Christmas, D, Jentzsch, I, Johnston, B, Sprengelmeyer, R, Matthews, K & Steele, JD 2016,

'A causal role for the anterior mid-cingulate cortex in negative affect and cognitive control' Brain, vol. 139, no. 6, pp. 1844-1854.
https://doi.org/10.1093/brain/aww069

Research output: Contribution To Journal



Gradin, VB, Pérez, A, Macfarlane, JA, Cavin, I, Waiter, G, Tone, EB, Dritschel, B, Maiche, A & Steele, JD 2016,

'Neural correlates of social exchanges during the Prisoner’s Dilemma game in depression' Psychological Medicine, vol. 46, no. 6, pp. 1289-1300.
https://doi.org/10.1017/S0033291715002834

Research output: Contribution To Journal



Tolomeo, S, Gray, S, Matthews, K, Steele, JD & Baldacchino, A 2016,

'Multifaceted impairments in impulsivity and brain structural abnormalities in opioid dependence and abstinence' Psychological Medicine, vol. 46, no. 13, pp. 2841-2853.
https://doi.org/10.1017/S0033291716001513

Research output: Contribution To Journal



Johnston, BA, Tolomeo, S, Gradin, V, Christmas, D, Matthews, K & Steele, JD 2015,

'Failure of hippocampal deactivation during loss events in treatment-resistant depression' Brain, vol. 138, no. 9, pp. 2766-2776.
https://doi.org/10.1093/brain/awv177

Research output: Contribution To Journal



Johnston, BA, Steele, JD, Tolomeo, S, Christmas, D & Matthews, K 2015,

'Structural MRI-based predictions in patients with treatment-refractory depression (TRD)' PLo S ONE, vol. 10, no. 7, 0132958.
https://doi.org/10.1371/journal.pone.0132958

Research output: Contribution To Journal



Gradin, VB, Pérez, A, Mac Farlane, JA, Cavin, I, Waiter, G, Engelmann, J, Dritschel, B, Pomi, A, Matthews, K & Steele, JD 2015,

'Abnormal brain responses to social fairness in depression: an f MRI study using the Ultimatum Game' Psychological Medicine, vol. 45, no. 6, pp. 1241-1251.
https://doi.org/10.1017/S0033291714002347

Research output: Contribution To Journal



Johnston, BA, Coghill, D, Matthews, K & Steele, JD 2015,

'Predicting methylphenidate response in attention deficit hyperactivity disorder: a preliminary study' Journal of Psychopharmacology, vol. 29, no. 1, pp. 24-30.
https://doi.org/10.1177/0269881114548438

Research output: Contribution To Journal



Johnston, BA, Mwangi, B, Matthews, K, Coghill, D, Konrad, K & Steele, JD 2014,

'Brainstem abnormalities in attention deficit hyperactivity disorder support high accuracy individual diagnostic classification' Human Brain Mapping, vol. 35, no. 10, pp. 5179-5189.
https://doi.org/10.1002/hbm.22542

Research output: Contribution To Journal



Sokunbi, MO, Gradin, VB, Waiter, GD, Cameron, GG, Ahearn, TS, Murray, AD, Steele, DJ & Staff, RT 2014,

'Nonlinear complexity analysis of brain f MRI signals in schizophrenia' PLo S ONE, vol. 9, no. 5.
https://doi.org/10.1371/journal.pone.0095146

Research output: Contribution To Journal



Gradin, VB, Baldacchino, A, Balfour, D, Matthews, K & Steele, JD 2014,

'Abnormal Brain Activity During a Reward and Loss Task in Opiate Dependent Patients Receiving Methadone Maintenance Therapy' Neuropsychopharmacology, vol. 39, no. 4, pp. 885-894.
https://doi.org/10.1038/npp.2013.289

Research output: Contribution To Journal



Christmas, D, Steele, JD, Tolomeo, S, Eljamel, MS & Matthews, K 2013,

'Vagus nerve stimulation for chronic major depressive disorder: 12-month outcomes in highly treatment-refractory patients' Journal of Affective Disorders, vol. 150, no. 3, pp. 1221-1225.
https://doi.org/10.1016/j.jad.2013.05.080

Research output: Contribution To Journal



Gradin, VB, Waiter, G, O'Connor, A, Romaniuk, L, Stickle, C, Matthews, K, Hall, J & Steele, JD 2013,

'Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia' Psychiatry Research: Neuroimaging, vol. 211, no. 2, pp. 104-111.
https://doi.org/10.1016/j.pscychresns.2012.06.003

Research output: Contribution To Journal



Brydges, NM, Whalley, HC, Jansen, MA, Merrifield, GD, Wood, ER, Lawrie, SM, Wynne, S-M, Day, M, Fleetwood-Walker, S, Steele, D, Marshall, I, Hall, J & Holmes, MC 2013,

'Imaging conditioned fear circuitry using awake rodent f MRI' PLo S ONE, vol. 9, no. 1, e54197, pp. 1-7.
https://doi.org/10.1371/journal.pone.0054197

Research output: Contribution To Journal



Johnston, BA, Mwangi, B, Matthews, K, Coghill, D & Steele, JD 2012,

'Predictive classification of individual magnetic resonance imaging scans from children and adolescents' European Child & Adolescent Psychiatry, vol. 22, no. 12, pp. 733-744.
https://doi.org/10.1007/s00787-012-0319-0

Research output: Contribution To Journal



Gradin, V, Gray, S, Mac Farlane, J, Waiter, G, Balfour, D, Matthews, K, Baldacchino, A & Steele, D 2012,

'Neural responses to rewards and punishments in patients with opiate dependence on methadone treatment: f NEMO study' European Neuropsychopharmacology, vol. 22, no. Suppl 2, P.6.c.008, pp. S402-S403.
https://doi.org/10.1016/S0924-977X(12)70628-4

Research output: Contribution To Journal



Gradin, VB, Waiter, G, Kumar, P, Stickle, C, Milders, M, Matthews, K, Reid, I, Hall, J & Steele, JD 2012,

'Abnormal neural responses to social exclusion in schizophrenia' PLo S ONE, vol. 7, no. 8, e42608, pp. -.
https://doi.org/10.1371/journal.pone.0042608

Research output: Contribution To Journal



Mwangi, B, Ebmeier, KP, Matthews, K & Steele, JD 2012,

'Multi-centre diagnostic classification of individual structural neuroimaging scans from patients with major depressive disorder' Brain, vol. 135, no. 5, pp. 1508-1521.
https://doi.org/10.1093/brain/aws084

Research output: Contribution To Journal



Perrin, JS, Merz, S, Bennett, DM, Currie, J, Steele, DJ, Reid, IC & Schwarzbauer, C 2012,

'Electroconvulsive therapy reduces frontal cortical connectivity in severe depressive disorder' Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 14, pp. 5464-5468.
https://doi.org/10.1073/pnas.1117206109

Research output: Contribution To Journal



Mwangi, B, Matthews, K & Steele, JD 2012,

'Prediction of illness severity in patients with major depression using structural MR brain scans' Journal of Magnetic Resonance Imaging, vol. 35, no. 1, pp. 64-71.
https://doi.org/10.1002/jmri.22806

Research output: Contribution To Journal



Sprengelmeyer, R, Steele, JD, Mwangi, B, Kumar, P, Christmas, D, Milders, M & Matthews, K 2011,

'The insular cortex and the neuroanatomy of major depression' Journal of Affective Disorders, vol. 133, no. 1-2, pp. 120-127.
https://doi.org/10.1016/j.jad.2011.04.004

Research output: Contribution To Journal



Gradin, V, Waiter, G, Kumar, P, Ahearn, T, Stickle, C, Milders, M, Matthews, K, Reid, I, Hall, J & Steele, JD 2011,

'Abnormal medial prefrontal cortex responses to social exclusion in schizophrenia: an FMRI study' European Neuropsychopharmacology, vol. 21, P.1.e.004, pp. S305-S305.
https://doi.org/10.1016/S0924-977X(11)70482-5

Research output: Contribution To Journal



Perrin, JS, Bennett, DM, Currie, J, Steele, JD & Reid, IC 2011,

'A MRI investigation of electroconvulsive therapy (ECT) for the treatment of depression' Journal of Psychopharmacology, vol. 25, no. 8, pp. A54-A54.

Research output: Contribution To Journal



Christmas, D, Eljamel, MS, Butler, S, Hazari, H, Mac Vicar, R, Steele, JD, Livingstone, A & Matthews, K 2011,

'Long term outcome of thermal anterior capsulotomy for chronic, treatment refractory depression' Journal of Neurology, Neurosurgery and Psychiatry, vol. 82, no. 6, pp. 594-600.
https://doi.org/10.1136/jnnp.2010.217901

Research output: Contribution To Journal



Gradin, VB, Kumar, P, Waiter, G, Ahearn, T, Stickle, C, Milders, M, Reid, I, Hall, J & Steele, JD 2011,

'Expected value and prediction error abnormalities in depression and schizophrenia' Brain, vol. 134, no. 6, pp. 1751-1764.
https://doi.org/10.1093/brain/awr059

Research output: Contribution To Journal



Currie, J, Buruju, D, Perrin, J, Feltovich, N, Reid, IC & Steele, JD 2011,

'Decision-making in schizophrenia studied within an economics game paradigm' Journal of Psychopharmacology, vol. 25, no. 8, TD24, pp. A71 .

Research output: Contribution To Journal



Gradin, V, Gountouna, V-E, Waiter, G, Ahearn, TS, Brennan, D, Condon, B, Marshall, I, Mc Gonigle, DJ, Murray, AD, Whalley, H, Cavanagh, J, Hadley, D, Lymer, K, Mc Intosh, A, Moorhead, TW, Job, D, Wardlaw, J, Lawrie, SM & Steele, JD 2010,

'Between- and within-scanner variability in the Cali Brain study n-back cognitive task' Psychiatry Research: Neuroimaging, vol. 184, no. 2, pp. 86-95.
https://doi.org/10.1016/j.pscychresns.2010.08.010

Research output: Contribution To Journal



Gradin, V, Kumar, P, Waiter, G, Ahearn, T, Reid, I, Stickle, C, Milders, M, Hall, J & Steele, JD 2010,

'Abnormalities in reward prediction error signals in depression and schizophrenia' European Neuropsychopharmacology, vol. 20, no. s3, pp. S173-S173.
https://doi.org/10.1016/S0924-977X(10)70149-8

Research output: Contribution To Journal



Gradin, VB, Kumar, P, Waiter, G, Ahearn, T, Reid, I, Stickle, C, Milders, M, Hall, J & Steele, JD 2010,

'Abnormalities in reward prediction error signals in depression and schizophrenia' European Neuropsychopharmacology, vol. 20, no. s1, pp. S67-S68.
https://doi.org/10.1016/S0924-977X(10)70079-1

Research output: Contribution To Journal



Gountouna, V-E, Job, DE, Mc Intosh, AM, Moorhead, TWJ, Lymer, GKL, Whalley, HC, Hall, J, Waiter, GD, Brennan, D, Mc Gonigle, DJ, Ahearn, TS, Cavanagh, J, Condon, B, Hadley, DM, Marshall, I, Murray, AD, Steele, JD, Wardlaw, JM & Lawrie, SM 2010,

'Functional Magnetic Resonance Imaging (f MRI) reproducibility and variance components across visits and scanning sites with a finger tapping task' Neuro Image, vol. 49, no. 1, pp. 552-560.
https://doi.org/10.1016/j.neuroimage.2009.07.026

Research output: Contribution To Journal



Kumar, P, Waiter, G, Ahearn, T, Milders, M, Reid, I & Steele, JD 2009,

'Abnormal brain responses during social inclusion in depressive illness and effect of acute anti-depressant medication' European Neuropsychopharmacology, vol. 19, no. S3, pp. S387-S387.
https://doi.org/10.1016/S0924-977X(09)70595-4

Research output: Contribution To Journal



Whalley, HC, Steele, JD, Mukherjee, P, Romaniuk, L, Mc Intosh, AM, Hall, J & Lawrie, SM 2009,

'Connecting the Brain and New Drug Targets for Schizophrenia' Current Pharmaceutical Design, vol. 15, no. 22, pp. 2615-2631.

Research output: Contribution To Journal



Hall, J, Romaniuk, L, Mc Intosh, AM, Steele, JD, Johnstone, EC & Lawrie, SM 2009,

'Associative learning and the genetics of schizophrenia' Trends in Neurosciences, vol. 32, no. 6, pp. 359-365.
https://doi.org/10.1016/j.tins.2009.01.011

Research output: Contribution To Journal



Kumar, P, Waiter, G, Ahearn, T, Milders, M, Reid, I & Steele, JD 2009,

'Frontal operculum temporal difference signals and social motor response learning' Human Brain Mapping, vol. 30, no. 5, pp. 1421-1430.
https://doi.org/10.1002/hbm.20611

Research output: Contribution To Journal



Moorhead, TWJ, Gountouna, V-E, Job, DE, Mc Intosh, AM, Romaniuk, L, Lymer, GKS, Whalley, HC, Waiter, GD, Brennan, D, Ahearn, TS, Cavanagh, J, Condon, B, Steele, JD, Wardlaw, JM & Lawrie, SM 2009,

'Prospective multi-centre Voxel Based Morphometry study employing scanner specific segmentations: procedure development using Cali Brain structural MRI data' BMC Medical Imaging, vol. 9, pp. 8.
https://doi.org/10.1186/1471-2342-9-8

Research output: Contribution To Journal



Kumar, P, Waiter, G, Ahearn, T, Milders, M, Reid, I & Steele, JD 2008,

'Abnormal temporal difference reward-learning signals in major depression' Brain, vol. 131, no. 8, pp. 2084-2093.
https://doi.org/10.1093/brain/awn136

Research output: Contribution To Journal



Steele, JD, Christmas, D, Eljamel, MS & Matthews, K 2008,

'Anterior cingulotomy for major depression: clinical outcome and relationship to lesion characteristics' Biological Psychiatry, vol. 63, no. 7, pp. 670-677.
https://doi.org/10.1016/j.biopsych.2007.07.019

Research output: Contribution To Journal



Rück, C, Karlsson, A, Nyman, H, Åsberg, M, Svanborg, P, Meyerson, BA, Ericson, K, Steele, JD & Edman, G 2008,

'Capsulotomy for obsessive-compulsive disorder: long-term follow-up of 25 patients' Archives of General Psychiatry, vol. 65, no. 8, pp. 914-922.
https://doi.org/10.1001/archpsyc.65.8.914

Research output: Contribution To Journal



Steele, JD, Dillon, JF, Plevris, JN, Hauer, JL, Bouchier, IAD & Hayes, PC 1994,

'Hand skin temperature changes in patients with chronic liver disease' Journal of Hepatology, vol. 21, no. 6, pp. 927-933.

Research output: Contribution To Journal



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