Colin Henderson

+44 (0)1382 383130
Senior Lecturer

Bio

Biography

My undergrdauate degree from the University of Edinburgh in Biochemistry (1981), was followed by a PhD in the Faculty of Medicine at the same institution. After undertaking a Celltech Training Fellowship at the MRC Reproductive Biology Unit in Edinburgh (1984-1987), I joined the Imperial Cancer Research Fund lab of Professor Roland Wolf, which relocated to the University of Dundee in January 1993. As part of ICRF, later Cancer Research UK, I became a senior, then Chief, Scientifc Officer, and later Associate, and then Staff, Scientist. I was appointed to an honorary lecturer position with the University of Dundee in 1999, formally joining the University in April 2011 as a Senior Lecturer in the School of Medicine.

I am an enthusiastic advocate for outreach, and believe passionately that it is our duty as academics and scientists to clearly and openly communicate our work to the public. Ihave been extensively involved for >20 years in science communication and public engagement, both internally (Lab Tours, Open Days) and externally (School visits, Race/Relay for Life, charity & fundraising groups). In 2012, I was Ambassador of the Year (Researcher) in the CRUK ‘Flame of Hope’ awards. I was joint recipient of the Ian Stevenson Award for Public Engagement in 2016, and in 2017 I was appointed become Academic Lead for Public Engagement/Wider Impact for the School of Medicine, and represent the School on the University’s Public Engagement Forum.

I chair the Medical School Biological Services management committee, and I am the School of Medicine Representative on the University Welfare and Ethical use of animals committee. I sit on the National Centre for Reduction, Refinement and Replacment (NC3Rs) Studentship Committee.

Research

Trained as a biochemist, I have over 30 years’ experience working across disciplines in the areas of toxicology, drug metabolism and molecular pharmacology, which has made me a leader in these fields, with an international reputation for innovation. For more than two decades I have been at the cutting edge of transgenic model development, culminating in the generation of genetically altered mice designed to closely mirror human drug metabolism. These unique humanised mouse models havethe potential to create a paradigm shift in pre-clinical drug testing and clinical trial design, particularly addressing the increasing use of drug combinations in oncology. 

Over the last 15 years, my sustained research contributions and extensive knowledge of transgenic design and strategies has established me at the forefront of this area and internationally recognised amongst my peers, and I am regularly invited to speak, chair and participate at national/international conferences and symposia. 

I have established many local, national and international collaborations with both academic and industrial partners, resulting in a strong and sustained publication record. As well as several book chapters and reviews, I have published more than 100 peer-reviewed journal articles; my h-factor is 44 (Google Scholar, February 2018http://tinyurl.com/hth7bzq). My expertise in mouse work, and knowledge of transgenics, has led to my involvement in numerous projects, both across the University and nationally/internationally. Since joining the University in 2011, I have been instrumental in securing more than £5M of grant funding, including two MRC Project grants (2017, 2018) worth >£2M. I regularly review manuscripts submitted for publication to a range of journals, and review grant applications for national funding bodies.

Teaching

Undergraduate: I deliver lectures to science and medical students, mainly in the area of toxicology, drug metabolism and transgenic models. I currently participate in BS50003 MSci Integrated Masters, BS42007 Cancer Biology, BS42027 Cancer Pharmacology, BMSc 40036, BS32029 Biomedical Sciences  and SSC components for Medicine.

Postgraduate: I have been involved in the supervision of a number of graduate students; I am currently primary supervisor to one graduate student. I also participate in, and help run, MRes Cancer Biology

PhD & MSc Examinations:I have been Convenor or Internal Examiner for MSc and PhD theses in the Medical School, and External Examiner at a number of UK academic institutions.

Publications

Mac Leod, AK, Lin, D, Huang, JT-J, Mc Laughlin, LA, Henderson, CJ & Wolf, CR 2018,

'Identification of novel pathways of osimertinib disposition and potential implications for the outcome of lung cancer therapy' Clinical Cancer Research, vol. 24, no. 9, pp. 2138-2147. DOI:
10.1158/1078-0432.CCR-17-3555

Research output: Contribution To Journal



Reed, L, Mrizova, I, Barta, F, Indra, R, Moserova, M, Kopka, K, Schmeiser, HH, Wolf, CR, Henderson, CJ, Stiborova, M, Phillips, DH & Arlt, VM 2018,

'Cytochrome b5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b5 /P450 reductase null (HBRN) mice' Archives of Toxicology. DOI:
10.1007/s00204-018-2162-7

Research output: Contribution To Journal



Mc Mahon, M, Ding, S, Acosta-Jimenez, LP, Frangova, TG, Henderson, CJ & Wolf, CR 2018,

'Measuring in vivo responses to endogenous and exogenous oxidative stress using a novel Heme Oxygenase 1 reporter mouse' Journal of Physiology, vol. 596, no. 1, pp. 105-127. DOI:
10.1113/JP274915

Research output: Contribution To Journal



Pandey, AV, Henderson, CJ, Ishii, Y, Kranendonk, M, Backes, WL & Zanger, UM 2017,

'Editorial: Role of protein-protein interactions in metabolism: Genetics, structure, function' Frontiers in Pharmacology, vol. 8, 881, pp. 1-3. DOI:
10.3389/fphar.2017.00881

Research output: Contribution To Journal



Lin, D, Kostov, R, Huang, J, Henderson, CJ & Wolf, C 2017,

'Novel Pathways Of Ponatinib Disposition Catalysed By CYP1A1 Involving Generation Of Potentially Toxic Metabolites' Journal of Pharmacology and Experimental Therapeutics, vol. 363, no. 1, pp. 12-19. DOI:
10.1124/jpet.117.243246

Research output: Contribution To Journal



Mac Leod, AK, Acosta-Jimenez, L, Coates, PJ, Mc Mahon, M, Carey, FA, Honda, T, Hayes, JD, Henderson, CJ & Wolf, CR 2017,

'Corrigendum to "Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer"' British Journal of Cancer, vol. 117, e1. DOI:
10.1038/bjc.2017.80

Research output: Contribution To Journal



Pouché , L, Vitobello, A, Römer, M, Glogovac, M, Mac Leod, AK, Ellinger-Ziegelbauer, H, Westphal, M, Dubost, V, Stiehl, DP, Dumotier, B, Fekete, A, Moulin, P, Zell, A, Schwarz, M, Moreno , R, Huang, JTJ, Elcombe, CR, Henderson, CJ, Wolf, CR, Moggs, JG & Terranova, R 2017,

'Xenobiotic CAR activators induce Dlk1-Dio3 locus non-coding RNA expression in mouse liver' Toxicological Sciences, vol. 158, no. 2, pp. 367-378. DOI:
10.1093/toxsci/kfx104

Research output: Contribution To Journal



Samuelsson, K, Scheer, N, Wilson, I, Wolf, C & Henderson, CJ 2017,

Genetically Humanized Animal Models. in S Chackalamannil, DP Rotella & SE Ward (eds), Comprehensive Medicinal Chemistry III. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, pp. 130-149. DOI:
10.1016/B978-0-12-409547-2.12376-5

Research output: Contribution To Book Anthology



Schiering, C, Wincent, E, Metidji, A, Iseppon, A, Li, Y, Potocnik, AJ, Omenetti, S, Henderson, CJ, Wolf, CR, Nebert, DW & Stockinger, B 2017,

'Feedback control of AHR signalling regulates intestinal immunity' Nature, vol. 542, no. 7640, pp. 242-245. DOI:
10.1038/nature21080

Research output: Contribution To Journal



Villa, M, Gialitakis, M, Tolaini, M, Ahlfors, H, Henderson, CJ, Wolf, CR, Brink, R & Stockinger, B 2017,

'Aryl hydrocarbon receptor is required for optimal B-cell proliferation' EMBO Journal, vol. 36, no. 1, pp. 116-128. DOI:
10.15252/embj.201695027

Research output: Contribution To Journal



Mac Leod, AK, Mc Laughlin, LA, Henderson, CJ & Wolf, CR 2017,

'Application of Mice Humanised for Cytochrome P450 CYP2D6 to the Study of Tamoxifen Metabolism and Drug-Drug Interaction with Antidepressants' Drug Metabolism and Disposition, vol. 45, no. 1, pp. 17-22. DOI:
10.1124/dmd.116.073437

Research output: Contribution To Journal



Mac Leod, AK, Acosta-Jimenez, L, Coates, PJ, Mc Mahon, M, Carey, FA, Honda, T, Henderson, CJ & Wolf, CR 2016,

'Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer' British Journal of Cancer, vol. 115, no. 12, pp. 1530-1539. DOI:
10.1038/bjc.2016.363

Research output: Contribution To Journal



Mc Mahon, M, Frangova, TG, Henderson, CJ & Wolf, CR 2016,

'Olaparib, monotherapy or with ionizing radiation, exacerbates DNA damage in normal tissues: insights from a new p21 reporter mouse' Molecular Cancer Research, vol. 14, no. 12, pp. 1195-1203. DOI:
10.1158/1541-7786.MCR-16-0108

Research output: Contribution To Journal



Takahashi, S, Fukami, T, Masuo, Y, Brocker, CN, Xie, C, Krausz, KW, Wolf, CR, Henderson, CJ & Gonzalez, FJ 2016,

'Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans' Journal of Lipid Research, vol. 57, pp. 2130-2037. DOI:
10.1194/jlr.M071183

Research output: Contribution To Journal



Wolf, CR, Kapelyukh, Y, Scheer, N & Henderson, CJ 2016,

Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs. in New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 edn, vol. 2016-January, RSC Drug Discovery Series, no. 49, vol. 2016-January, Royal Society of Chemistry, pp. 152-176. DOI:
10.1039/9781782622376-00152

Research output: Contribution To Book Anthology



Mc Millan, DH, van der Velden, JLJ, Lahue, KG, Quan, X, Schneider, RW, Iberg, MS, Nolin, JD, Abdalla, S, Casey, DT, Tew, KD, Townsend, DM, Henderson, CJ, Wolf, CR, Butnor, KJ, Taatjes, DJ, Budd, RC, Irvin, CG, van der Vliet, A, Flemer, S, Anathy, V & Janssen-Heininger, YMW 2016,

'Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π' JCI Insight, vol. 1, no. 8, e85717. DOI:
10.1172/jci.insight.85717

Research output: Contribution To Journal



Scott, EE, Wolf, CR, Otyepka, M, Humphreys, SC, Reed, JR, Henderson, CJ, Mc Laughlin, LA, Paloncyova, M, Navratilova, V, Berka, K, Anzenbacher, P, Dahal, UP, Barnaba, C, Brozik, JA, Jones, JP, Estrada, F, Laurence, JS, Park, JW & Backes, WL 2016,

'The role of protein-protein and protein-membrane Interactions on P450 function' Drug Metabolism and Disposition, vol. 44, no. 4, pp. 576-590. DOI:
10.1124/dmd.115.068569

Research output: Contribution To Journal



Mac Leod, AK, Mc Laughlin, LA, Henderson, CJ & Wolf, CR 2015,

'Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models' Cancer Research, vol. 75, no. 21, pp. 4573-4581. DOI:
10.1158/0008-5472.CAN-15-1454

Research output: Contribution To Journal



Mc Garry, DJ, Chakravarty, P, Wolf, CR & Henderson, CJ 2015,

'Altered protein S-glutathionylation identifies a potential mechanism of resistance to Acetaminophen-induced hepatotoxicity' Journal of Pharmacology and Experimental Therapeutics, vol. 355, no. 2, pp. 137-144. DOI:
10.1124/jpet.115.227389

Research output: Contribution To Journal



Scheer, N, Kapelyukh, Y, Rode, A, Oswald, S, Busch, D, Mc Laughlin, LA, Lin, D, Henderson, CJ & Wolf, CR 2015,

'Defining human pathways of drug metabolism in vivo through the development of a multiple humanized mouse model' Drug Metabolism and Disposition, vol. 43, no. 11, pp. 1679-1690. DOI:
10.1124/dmd.115.065656

Research output: Contribution To Journal



Braeuning, A, Henderson, CJ, Wolf, CR & Schwarz, M 2015,

'Model systems for understanding mechanisms of non-genotoxic carcinogenesis: response' Toxicological Sciences, vol. 147, no. 2, pp. 299-300. DOI:
10.1093/toxsci/kfv186

Research output: Contribution To Journal



Kostov, RV, Knatko, EV, Mc Laughlin, LA, Henderson, CJ, Zheng, S, Huang, JTJ, Honda, T & Dinkova-Kostova, AT 2015,

'Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action' Biochemical and Biophysical Research Communications, vol. 465, no. 3, pp. 402-407. DOI:
10.1016/j.bbrc.2015.08.016

Research output: Contribution To Journal



Mc Garry, DJ, Chen, W, Chakravarty, P, Lamont, DL, Wolf, CR & Henderson, CJ 2015,

'Proteome-wide identification and quantification of S-glutathionylation targets in mouse liver' Biochemical Journal, vol. 469, no. 1, pp. 25-32. DOI:
10.1042/BJ20141256

Research output: Contribution To Journal



Henderson, CJ, Cameron, AR, Chatham, L, Stanley, LA & Wolf, CR 2015,

'Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability' Toxicological Sciences, vol. 145, no. 1, pp. 138-148. DOI:
10.1093/toxsci/kfv039

Research output: Contribution To Journal



Henderson, CJ, Mc Laughlin, LA, Scheer, N, Stanley, LA & Wolf, CR 2015,

'Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivo' Molecular Pharmacology, vol. 87, no. 4, pp. 733-739. DOI:
10.1124/mol.114.097394

Research output: Contribution To Journal



Mac Leod, AK, Fallon, PG, Sharp, S, Henderson, CJ, Wolf, CR & Huang, JT-J 2015,

'An enhanced in vivo stable isotope labeling by amino acids in cell culture (SILAC) model for quantification of drug metabolism enzymes' Molecular & Cellular Proteomics, vol. 14, no. 3, pp. 750-760. DOI:
10.1074/mcp.M114.043661

Research output: Contribution To Journal



Henderson, CJ, Mc Laughlin, LA, Osuna-Cabello, M, Taylor, M, Gilbert, I, Mc Laren, AW & Wolf, CR 2015,

'Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability' Biochemical Journal, vol. 465, no. 3, pp. 479-488. DOI:
10.1042/BJ20140582

Research output: Contribution To Journal



Pajaud, J, Ribault, C, Ben Mosbah, I, Rauch, C, Henderson, C, Bellaud, P, Aninat, C, Loyer, P, Morel, F & Corlu, A 2015,

'Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration' Cell Death and Disease, vol. 6, e1598. DOI:
10.1038/cddis.2014.562

Research output: Contribution To Journal



Arlt, V, Henderson, CJ, Wolf, CR, Stiborová, M & Phillips, DH 2015,

'The Hepatic Reductase Null (HRN™) and Reductase Conditional Null (RCN) mouse models as suitable tools to study metabolism, toxicity and carcinogenicity of environmental pollutants' Toxicology Research, vol. 4, no. 3, pp. 548-562. DOI:
10.1039/C4TX00116H

Research output: Contribution To Journal



Mc Mahon, M, Campbell, KH, Mac Leod, AK, Mc Laughlin, LA, Henderson, CJ & Wolf, CR 2014,

'HDAC inhibitors increase NRF2-signaling in tumour cells and blunt the efficacy of co-adminstered cytotoxic agents' PLo S ONE, vol. 9, no. 11, e114055. DOI:
10.1371/journal.pone.0114055

Research output: Contribution To Journal



Henderson, CJ, Mc Laren, AW & Wolf, CR 2014,

'In vivo regulation of human glutathione transferase GSTP by chemopreventive agents' Cancer Research, vol. 74, no. 16, pp. 4378-4387. DOI:
10.1158/0008-5472.CAN-14-0792

Research output: Contribution To Journal



Braeuning, A, Gavrilov, A, Brown, S, Wolf, CR, Henderson, CJ & Schwarz, M 2014,

'Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXR' Toxicological Sciences, vol. 140, no. 2, pp. 259-70. DOI:
10.1093/toxsci/kfu099

Research output: Contribution To Journal



Scheer, N, Mc Laughlin, LA, Rode, A, Mac Leod, AK, Henderson, CJ & Wolf, CR 2014,

'Deletion of 30 Murine Cytochrome p450 Genes Results In Viable Mice With Compromised Drug Metabolism' Drug Metabolism and Disposition, vol. 42, no. 6, pp. 1022-1030. DOI:
10.1124/dmd.114.057885

Research output: Contribution To Journal



Stiborová, M, Moserová, M, Černá, V, Indra, R, Dračínský, M, Šulc, M, Henderson, CJ, Wolf, CR, Schmeiser, HH, Phillips, DH, Frei, E & Arlt, VM 2014,

'Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions' Toxicology, vol. 318, no. 1, pp. 1-12. DOI:
10.1016/j.tox.2014.02.002

Research output: Contribution To Journal



Macleod, AK, Zang, T, Riches, Z, Henderson, CJ, Wolf, CR & Huang, JT-J 2014,

'A Targeted in Vivo SILAC Approach for Quantification of Drug Metabolism Enzymes: Regulation by the Constitutive Androstane Receptor' Journal of Proteome Research, vol. 13, no. 2, pp. 866-874. DOI:
10.1021/pr400897t

Research output: Contribution To Journal



Henderson, CJ, Mc Laughlin, LA, Finn, RD, Ronseaux, S, Kapelyukh, Y & Wolf, CR 2014,

'A role for cytochrome b5 in the in vivo disposition of anti-cancer and cytochrome P450 probe drugs in mice' Drug Metabolism and Disposition, vol. 42, no. 1, pp. 70-77. DOI:
10.1124/dmd.113.055277

Research output: Contribution To Journal



Luisier, R, Lempiäinen, H, Scherbichler, N, Braeuning, A, Geissler, M, Dubost, V, Müller, A, Scheer, N, Chibout, S-D, Hara, H, Picard, F, Theil, D, Couttet, P, Vitobello, A, Grenet, O, Grasl-Kraupp, B, Ellinger-Ziegelbauer, H, Thomson, JP, Meehan, RR, Elcombe, CR, Henderson, CJ, Wolf, CR, Schwarz, M, Moulin, P, Terranova, R & Moggs, JG 2014,

'Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane X receptors' Toxicological Sciences, vol. 139, no. 2, pp. 501-511. DOI:
10.1093/toxsci/kfu038

Research output: Contribution To Journal



Ismail, HM, O'Neill, PM, Hong, DW, Finn, RD, Henderson, CJ, Wright, AT, Cravatt, BF, Hemingway, J & Paine, MJI 2013,

'Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions' Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 49, pp. 19766-19771. DOI:
10.1073/pnas.1320185110

Research output: Contribution To Journal



Henderson, CJ, Mc Laughlin, LA & Wolf, CR 2013,

'Evidence that Cytochrome b5 and Cytochrome b5 Reductase Can Act as Sole Electron Donors to the Hepatic Cytochrome P450 System' Molecular Pharmacology, vol. 83, no. 6, pp. 1209-1217. DOI:
10.1124/mol.112.084616

Research output: Contribution To Journal



Carvalho, AN, Marques, C, Rodrigues, E, Henderson, CJ, Wolf, CR, Pereira, P & Gama, MJ 2013,

'Ubiquitin-proteasome system impairment and MPTP-induced oxidative stress in the brain of C57BL/6 wild-type and GSTP knockout mice' Molecular Neurobiology, vol. 47, no. 2, pp. 662-72. DOI:
10.1007/s12035-012-8368-4

Research output: Contribution To Journal



Riddick, DS, Ding, X, Wolf, CR, Porter, TD, Pandey, AV, Zhang, Q-Y, Gu, J, Finn, RD, Ronseaux, S, Mc Laughlin, LA, Henderson, CJ, Zou, L & Flück, CE 2013,

'NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology' Drug Metabolism and Disposition, vol. 41, no. 1, pp. 12-23. DOI:
10.1124/dmd.112.048991

Research output: Contribution To Journal



Plitzko, B, Ott, G, Reichmann, D, Henderson, CJ, Wolf, CR, Mendel, R, Bittner, F, Clement, B & Havemeyer, A 2013,

'The involvement of mitochondrial amidoxime reducing components 1 and 2 and mitochondrial cytochrome b5 in N-reductive metabolism in human cells' Journal of Biological Chemistry, vol. 288, no. 28, pp. 20228-20237. DOI:
10.1074/jbc.M113.474916

Research output: Contribution To Journal



Wisniewska, A, Niemira, M, Jagiello, K, Potega, A, Swist, M, Henderson, C, Skwarska, A, Augustin, E, Konopa, J & Mazerska, Z 2012,

'Diminished toxicity of C-1748, 4-methyl-9-hydroxyethylamino-1-nitroacridine, compared with its demethyl analog, C-857, corresponds to its resistance to metabolism in Hep G2 cells' Biochemical Pharmacology, vol. 84, no. 1, pp. 30-42. DOI:
10.1016/j.bcp.2012.03.013

Research output: Contribution To Journal



Castro-Caldas, M, Carvalho, AN, Rodrigues, E, Gama, MJ, Henderson, C & Wolf, CR 2012,

'Glutathione S-Transferase pi Mediates MPTP-Induced c-Jun N-Terminal Kinase Activation in the Nigrostriatal Pathway' Molecular Neurobiology, pp. 1-12. DOI:
10.1007/s12035-012-8266-9

Research output: Contribution To Journal



Arlt, VM, Poirier, MC, Sykes, SE, John, K, Moserova, M, Stiborova, M, Wolf, CR, Henderson, CJ & Phillips, DH 2012,

'Exposure to benzo[a]pyrene of hepatic cytochrome P450 reductase null (HRN) and P450 reductase conditional null (RCN) mice: detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and P-postlabelling' Toxicology Letters, vol. 213, no. 2, pp. 160-166. DOI:
10.1016/j.toxlet.2012.06.016

Research output: Contribution To Journal



Castro-Caldas, M, Carvalho, AN, Rodrigues, E, Henderson, CJ, Wolf, CR, Rodrigues, CMP & Gama, MJ 2012,

'Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease' Molecular Neurobiology, vol. 46, no. 2, pp. 475-486. DOI:
10.1007/s12035-012-8295-4

Research output: Contribution To Journal



Mc Garry, DJ, Wolf, CR & Henderson, CJ 2011,

'Non-catalytic mechanisms involved in glutathione Stransferase Pi mediated cytoprotection' Toxicology, vol. 290, no. 2-3, pp. 130-130. DOI:
10.1016/j.tox.2011.09.052

Research output: Contribution To Journal



Arlt, VM, Singh, R, Stiborova, M, da Costa, GG, Frei, E, Evans, JD, Farmer, PB, Wolf, CR, Henderson, CJ & Phillips, DH 2011,

'Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 reductase conditional null mice' Drug Metabolism and Disposition, vol. 39, no. 12, pp. 2169-2173. DOI:
10.1124/dmd.111.041343

Research output: Contribution To Journal



Henderson, CJ, Ritchie, KJ, Mc Laren, A, Chakravarty, P & Wolf, CR 2011,

'Increased Skin Papilloma Formation in Mice Lacking Glutathione Transferase GSTP' Cancer Research, vol. 71, no. 22, pp. 7048-7060. DOI:
10.1158/0008-5472.CAN-11-0882

Research output: Contribution To Journal



Hawksworth, GM, Farooq, M, Henderson, CJ & Weaver, RJ 2011,

'Regulation of hepatic uptake and efflux transporters in vitro' Drug Metabolism Reviews, vol. 43, pp. 209-209. DOI:
10.3109/03602532.2011.629832

Research output: Contribution To Journal



Potega, A, Dabrowska, E, Niemira, M, Kot-Wasik, A, Ronseaux, S, Henderson, CJ, Wolf, CR & Mazerska, Z 2011,

'The Imidazoacridinone Antitumor Drug, C-1311, Is Metabolized by Flavin Monooxygenases but Not by Cytochrome P450s' Drug Metabolism and Disposition, vol. 39, no. 8, pp. 1423-1432. DOI:
10.1124/dmd.111.038984

Research output: Contribution To Journal



Finn, RD, Mc Laughlin, LA, Hughes, C, Song, C, Henderson, CJ & Wolf, CR 2011,

'Cytochrome b (5) null mouse: a new model for studying inherited skin disorders and the role of unsaturated fatty acids in normal homeostasis' Transgenic Research, vol. 20, no. 3, pp. 491-502. DOI:
10.1007/s11248-010-9426-1

Research output: Contribution To Journal



Henderson, CJ & Wolf, CR 2011,

'Knockout and transgenic mice in glutathione transferase research' Drug Metabolism Reviews, vol. 43, no. 2, pp. 152-164. DOI:
10.3109/03602532.2011.562900

Research output: Contribution To Journal



Levova, K, Moserova, M, Kotrbova, V, Sulc, M, Henderson, CJ, Wolf, CR, Phillips, DH, Frei, E, Schmeiser, HH, Mares, J, Arlt, VM & Stiborova, M 2011,

'Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model' Toxicological Sciences, vol. 121, no. 1, pp. 43-56. DOI:
10.1093/toxsci/kfr050

Research output: Contribution To Journal



Vaughn, MP, Shinohara, DB, Castagna, N, Hicks, JL, Netto, G, De Marzo, AM, Speed, TJ, Reichert, ZR, Kwabi-Addo, B, Henderson, CJ, Wolf, CR, Yegnasubramanian, S & Nelson, WG 2011,

'Humanizing π-class glutathione S-transferase regulation in a mouse model alters liver toxicity in response to acetaminophen overdose' PLo S ONE, vol. 6, no. 10, e25707, pp. -. DOI:
10.1371/journal.pone.0025707

Research output: Contribution To Journal



Wolf, CR, Elcombe, C, Rode, A, Scheer, N, Bower, C & Henderson, C 2011,

'Role of CAR and PXR in xenobiotic toxicity' Toxicology Letters, vol. 205, pp. S13. DOI:
10.1016/j.toxlet.2011.05.1049

Research output: Contribution To Journal



Mc Garry, DJ, Wolf, CR & Henderson, CJ 2010,

'Non-catalytic mechanisms involved in glutathione S-transferase pi mediated cytoprotection' Toxicology, vol. 278, no. 3, pp. 371-372. DOI:
10.1016/j.tox.2010.08.131

Research output: Contribution To Journal



Singh, R, Arlt, VM, Henderson, CJ, Phillips, DH, Farmer, PB & da Costa, GG 2010,

'Detection and quantitation of N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-Phenylimidazo[4,5-b]pyridine adducts in DNA using online column-switching liquid chromatography tandem mass spectrometry' Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, vol. 878, no. 23, pp. 2155-2162. DOI:
10.1016/j.jchromb.2010.06.008

Research output: Contribution To Journal



Ross, J, Plummer, SM, Rode, A, Scheer, N, Bower, CC, Vogel, O, Henderson, CJ, Wolf, CR & Elcombe, CR 2010,

'Human Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) Support the Hypertrophic but not the Hyperplastic Response to the Murine Nongenotoxic Hepatocarcinogens Phenobarbital and Chlordane In Vivo' Toxicological Sciences, vol. 116, no. 2, pp. 452-466. DOI:
10.1093/toxsci/kfq118

Research output: Contribution To Journal



Mc Laughlin, LA, Ronseaux, S, Finn, RD, Henderson, CJ & Wolf, CR 2010,

'Deletion of Microsomal Cytochrome b(5) Profoundly Affects Hepatic and Extrahepatic Drug Metabolism' Molecular Pharmacology, vol. 78, no. 2, pp. 269-278. DOI:
10.1124/mol.110.064246

Research output: Contribution To Journal



Arlt, VM, Henderson, CJ, Wolf, CR, Phillips, DH & Stiborova, M 2010,

'The Hepatic cytochrome P450 reductase null (HRN) mouse model as a tool to study xenobiotic metabolism' Naunyn-Schmiedeberg's Archives of Pharmacology, vol. 381, pp. 83-83.

Research output: Contribution To Journal



Ritchie, KJ, Walsh, S, Sansom, OJ, Henderson, CJ & Wolf, CR 2009,

'Markedly enhanced colon tumorigenesis in Apc(Min) mice lacking glutathione S-transferase Pi' Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 49, pp. 20859-20864. DOI:
10.1073/pnas.0911351106

Research output: Contribution To Journal



Schmidt, K, Hughes, C, Chudek, JA, Goodyear, SR, Aspden, RM, Talbot, R, Gundersen, TE, Blomhoff, R, Henderson, C, Wolf, CR & Tickle, C 2009,

'Cholesterol Metabolism: the Main Pathway Acting Downstream of Cytochrome P450 Oxidoreductase in Skeletal Development of the Limb' Molecular and Cellular Biology, vol. 29, no. 10, pp. 2716-2729. DOI:
10.1128/MCB.01638-08

Research output: Contribution To Journal



Gama, MJ, Castro-Caldas, M, Carvalho, AN, Rodrigues, E, Henderson, CJ & Wolf, CR 2009,

'GSTpi Mediates MPTP-induced JNK Activation in the Nigrostriatal Pathway' Drug Metabolism Reviews, vol. 41, pp. 29-30.

Research output: Contribution To Journal



Finn, RD, Henderson, CJ, Scott, CL & Wolf, CR 2009,

'Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway' Biochemical Journal, vol. 417, no. 1, pp. 43-54. DOI:
10.1042/BJ20080740

Research output: Contribution To Journal



Henderson, CJ, Scheer, N & Wolf, CR 2009,

'Advances in the generation of mouse models to elucidate the pathways of drug metabolism in rodents and man' Expert Review of Clinical Pharmacology, vol. 2, no. 2, pp. 105-109. DOI:
10.1586/17512433.2.2.105

Research output: Contribution To Journal



Bradshaw, TD, Wren, JE, Bruce, M, Barrett, DA, Leong, C-O, Gaskell, M, Wright, EK, Farmer, PB, Henderson, CJ, Wolf, R & Stevens, MFG 2009,

'Preclinical toxicokinetic evaluation of Phortress [2-(4-amino-3- methylphenyl)-5-fluorobenzothiazole lysylamide dihydrochloride] in two rodent species' Pharmacology, vol. 83, no. 2, pp. 99-109. DOI:
10.1159/000183846

Research output: Contribution To Journal



Sim, SC, Miller, WL, Zhong, X-B, Arlt, W, Ogata, T, Ding, X, Wolf, CR, Flueck, CE, Pandey, AV, Henderson, CJ, Porter, TD, Daly, AK, Nebert, DW & Ingelman-Sundberg, M 2009,

'Nomenclature for alleles of the cytochrome P450 oxidoreductase gene' Pharmacogenetics and Genomics, vol. 19, no. 7, pp. 565-566. DOI:
10.1097/FPC.0b013e32832af5b7

Research output: Contribution To Journal



Zhou, J, Wolf, CR, Henderson, CJ, Cai, Y, Board, PG, Foster, PS & Webb, DC 2008,

'Glutathione Transferase P1 An Endogenous Inhibitor of Allergic Responses in a Mouse Model of Asthma' American Journal of Respiratory and Critical Care Medicine, vol. 178, no. 12, pp. 1202-1210. DOI:
10.1164/rccm.200801-178OC

Research output: Contribution To Journal



Finn, RD, Mc Laughlin, LA, Ronseaux, S, Rosewell, I, Houston, JB, Henderson, CJ & Wolf, CR 2008,

'Defining the in Vivo Role for Cytochrome b(5) in Cytochrome P450 Function through the Conditional Hepatic Deletion of Microsomal Cytochrome b(5)' Journal of Biological Chemistry, vol. 283, no. 46, pp. 31385-31393. DOI:
10.1074/jbc.M803496200

Research output: Contribution To Journal



Mc Laughlin, LA, Dickmann, LJ, Wolf, CR & Henderson, CJ 2008,

'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening' Drug Metabolism and Disposition, vol. 36, no. 7, pp. 1322-1331. DOI:
10.1124/dmd.108.021261

Research output: Contribution To Journal



Arlt, VM, Stiborova, M, Henderson, CJ, Thiemann, M, Frei, E, Aimova, D, Singh, R, da Costa, GG, Schmitz, OJ, Farmer, PB, Wolf, CR & Phillips, DH 2008,

'Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice' Carcinogenesis, vol. 29, no. 3, pp. 656-665. DOI:
10.1093/carcin/bgn002

Research output: Contribution To Journal



Stiborova, M, Arlt, VM, Henderson, CJ, Wolf, CR, Kotrbova, V, Moserova, M, Hudecek, J, Phillips, DH & Frei, E 2008,

'Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse' Toxicology and Applied Pharmacology, vol. 226, no. 3, pp. 318-327. DOI:
10.1016/j.taap.2007.09.017

Research output: Contribution To Journal



Potega, A, Ronseaux, S, Henderson, C, Konopa, J & Mazerska, Z 2008,

'THE ROLE OF HEPATIC CYTOCHROME P-450 ENZYMES IN METABOLISM OF IMIDAZOACRIDINONE ANTITUMOR AGENT, C-1311 (SYMADEX): STUDIES WITH THE HEPATIC NADPH: CYTOCHROME P450 REDUCTASE NULL MICE' Drug Metabolism Reviews, vol. 40, pp. 59-60.

Research output: Contribution To Journal



Wang, XJ, Hayes, JD, Henderson, CJ & Wolf, CR 2007,

'Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha' Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 49, pp. 19589-19594. DOI:
10.1073/pnas.0709483104

Research output: Contribution To Journal



Mutch, DM, Klocke, B, Morrison, P, Murray, CA, Henderson, CJ, Seifert, M & Williamson, G 2007,

'The disruption of hepatic cytochrome P450 reductase afters mouse lipid metabolism' Journal of Proteome Research, vol. 6, no. 10, pp. 3976-3984. DOI:
10.1021/pr0700448

Research output: Contribution To Journal



Le Pla, RC, Ritchie, KJ, Henderson, CJ, Wolf, CR, Harrington, CF & Farmer, PB 2007,

'Development of a liquid Chromatography-Electrospray ionization tandem mass spectrometry method for detecting Oxaliplatin-DNA intrastrand cross-links in biological samples' Chemical Research in Toxicology, vol. 20, no. 8, pp. 1177-1182. DOI:
10.1021/tx700088j

Research output: Contribution To Journal



Finn, RD, Mc Laren, AW, Carrie, D, Henderson, CJ & Wolf, CR 2007,

'Conditional deletion of cytochrome P450 oxidoreductase in the liver and gastrointestinal tract: A new model for studying the functions of the P450 system' Journal of Pharmacology and Experimental Therapeutics, vol. 322, no. 1, pp. 40-47. DOI:
10.1124/jpet.107.121780

Research output: Contribution To Journal



Arlt, VM, Stiborova, M, Henderson, CJ, Thiemann, M, Frei, E, Singh, R, da Costa, GG, Schmitz, OJ, Farmer, PB, Wolf, CR & Phillips, DH 2007,

'Exposure to benzo[A]pyrene in the hepatic cytochrome p450 oxidoreductase null mouse: detoxification by hepatic cytochrome p450 is more important than metabolic activation' Naunyn-Schmiedeberg's Archives of Pharmacology, vol. 375, no. Supplement 1, 352, pp. 73-73.

Research output: Contribution To Journal



Ritchie, KJ, Henderson, CJ, Wang, X-J, Vassieva, O, Carrie, D, Farmer, PB, Gaskell, M, Park, K & Wolf, CR 2007,

'Glutathione transferase π plays a critical role in the development of lung carcinogenesis following exposure to tobacco-related carcinogens and urethane' Cancer Research, vol. 67, no. 19, pp. 9248-9257. DOI:
10.1158/0008-5472.CAN-07-1764

Research output: Contribution To Journal



Woods, CG, Andersen, ME, Zhang, Q, Thomas, RS, Henderson, CJ, Wolf, CR & Pi, J 2007,

'Activation of Nrf2 and cellular inflammatory response by hypochlorous acid' Free Radical Biology and Medicine, vol. 43, pp. S160-S160.

Research output: Contribution To Journal



Mutch, DM, Crespy, V, Clough, J, Henderson, CJ, Lariani, S, Mansourian, R, Moulin, J, Wolf, CR & Williamson, G 2006,

'Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver' American Journal of Physiology-Gastrointestinal and Liver Physiology, vol. 291, no. 1, pp. G63-G72. DOI:
10.1152/ajpgi.00565.2005

Research output: Contribution To Journal



Arlt, VM, Henderson, CJ, Wolf, CR, Schmeiser, HH, Phillips, DH & Stiborova, M 2006,

'Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases' Cancer Letters, vol. 234, no. 2, pp. 220-231. DOI:
10.1016/j.canlet.2005.03.035

Research output: Contribution To Journal



Henderson, CJ, Pass, GJ & Wolf, CR 2006,

'The hepatic cytochrome P450 reductase null mouse as a tool to identify a successful candidate entity' Toxicology Letters, vol. 162, no. 1, pp. 111-117. DOI:
10.1016/j.toxlet.2005.10.016

Research output: Contribution To Journal



Wang, XJ, Chamberlain, M, Vassieva, O, Henderson, CJ & Wolf, CR 2005,

'Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase (POR) null mice' Biochemical Journal, vol. 388, no. 3, pp. 857-867. DOI:
10.1042/BJ20042087

Research output: Contribution To Journal



Pass, GJ, Carrie, D, Boylan, M, Lorimore, S, Wright, E, Houston, B, Henderson, CJ & Wolf, CR 2005,

'Role of hepatic cytochrome P450s in the pharmacokinetics and toxicity of cyclophosphamide: studies with the hepatic cytochrome P450 reductase null mouse' Cancer Research, vol. 65, no. 10, pp. 4211-4217. DOI:
10.1158/0008-5472.CAN-04-4103

Research output: Contribution To Journal



Arlt, VM, Stiborova, M, Henderson, CJ, Osborne, MR, Bieler, CA, Frei, E, Martinek, V, Sopko, B, Wolf, CR, Schmeiser, HH & Phillips, DH 2005,

'Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H: quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols' Cancer Research, vol. 65, no. 7, pp. 2644-2652. DOI:
10.1158/0008-5472.CAN-04-3544

Research output: Contribution To Journal



Campbell, SJ, Henderson, CJ, Anthony, DC, Davidson, D, Clark, AJ & Wolf, CR 2005,

'The murine Cyp1a1 gene is expressed in a restricted spatial and temporal pattern during embryonic development' Journal of Biological Chemistry, vol. 280, no. 7, pp. 5828-5835. DOI:
10.1074/jbc.M412899200

Research output: Contribution To Journal



Henderson, CJ & Wolf, CR 2005,

Disruption of the glutathione transferase Pi class genes. in H Sies & L Packer (eds), Gluthione transferases and gamma-glutamyl transpeptidases. Methods in Enzymology, vol. 401, Academic Press, San Diego, pp. 116-135. DOI:
10.1016/S0076-6879(05)01007-4

Research output: Contribution To Book Anthology



Mc Walter, GK, Higgins, LG, Mc Lellan, LI, Henderson, CJ, Song, L, Thornalley, PJ, Itoh, K, Yamamoto, M & Hayes, JD 2004,

'Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates' Journal of Nutrition, vol. 134, no. 12, pp. 3499S-3506S.

Research output: Contribution To Journal



Otto, DME, Henderson, CJ, Carrie, D, Davey, M, Gundersen, TE, Blomhoff, R, Adams, RH, Tickle, C & Wolf, CR 2003,

'Identification of novel roles of the cytochrome P450 system in early embryogenesis: effects on vasculogenesis and retinoic acid homeostasis' Molecular and Cellular Biology, vol. 23, no. 17, pp. 6103-6116. DOI:
10.1128/MCB.23.17.6103-6116.2003

Research output: Contribution To Journal



Elsby, R, Kitteringham, NR, Goldring, CE, Lovatt, CA, Chamberlain, M, Henderson, CJ, Wolf, CR & Park, BK 2003,

'Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi' Journal of Biological Chemistry, vol. 278, no. 25, pp. 22243-22249. DOI:
10.1074/jbc.M301211200

Research output: Contribution To Journal



Kitteringham, NR, Powell, H, Hamlett, J, Hamlett, J, Lovatt, C, Elsby, R, Henderson, CJ, Wolf, CR, Pennington, SR & Park, BK 2003,

'Protein expression profiling of glutathione S-transferase pi null mice as a strategy to identify potential markers of resistance to paracetamol-induced toxicity in the liver' Proteomics, vol. 3, no. 2, pp. 191-207. DOI:
10.1002/pmic.200390028

Research output: Contribution To Journal



Henderson, CJ, Otto, DME, Carrie, D, Magnuson, MA, Mc Laren, AW, Rosewell, I & Wolf, CR 2003,

'Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase' Journal of Biological Chemistry, vol. 278, no. 15, pp. 13480-13486. DOI:
10.1074/jbc.M212087200

Research output: Contribution To Journal



Henderson, CJ, Otto, DME, Mc Laren, AW, Carrie, D & Wolf, CR 2003,

'Knockout mice in xenobiotic metabolism' Drug Metabolism Reviews, vol. 35, no. 4, pp. 385-392. DOI:
10.1081/DMR-120026869

Research output: Contribution To Journal



Catania, JM, Parrish, AR, Kirkpatrick, DS, Chitkara, M, Bowden, GT, Henderson, CJ, Wolf, CR, Clark, AJ, Brendel, K, Fisher, RL & Gandolfi, AJ 2003,

'Precision-cut tissue slices from transgenic mice as an in vitro toxicology system' Toxicology in Vitro, vol. 17, no. 2, pp. 201-205. DOI:
10.1016/S0887-2333(03)00004-3

Research output: Contribution To Journal



Chanas, SA, Jiang, Q, Mc Mahon, M, Mc Walter, GK, Mc Lellan, LI, Elcombe, CR, Henderson, CJ, Wolf, CR, Moffat, GJ, Itoh, K, Yamamoto, M & Hayes, JD 2002,

'Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice' Biochemical Journal, vol. 365, no. Pt 2, pp. 405-16. DOI:
10.1042/BJ20020320

Research output: Contribution To Journal



Ruscoe, JE, Rosario, LA, Wang, T, Gate, L, Arifoglu, P, Wolf, CR, Henderson, CJ, Ronai, Z & Tew, KD 2001,

'Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GST ∏) influences cell proliferation pathways' Journal of Pharmacology and Experimental Therapeutics, vol. 298, no. 1, pp. 339-345.

Research output: Contribution To Journal



Mc Mahon, M, Itoh, K, Yamamoto, M, Chanas, SA, Henderson, CJ, Mc Lellan, LI, Wolf, CR, Cavin, C & Hayes, JD 2001,

'The Cap ‘n’ Collar Basic Leucine Zipper Transcription Factor Nrf2 (NF-E2 p45-related Factor 2) Controls Both Constitutive and Inducible Expression of Intestinal Detoxification and Glutathione Biosynthetic Enzymes' Cancer Research, vol. 61, no. 8, pp. 3299-3307.

Research output: Contribution To Journal



Mc Maghon, M, Chanas, SA, Henderson, CJ, Wolf, CR, Yamamoto, M & Hayes, JD 2001,

'The Nrf2 transcription factor regulates basal expression of class Alpha and class Mu glutathione S-transferases in the mouse, but not necessarily their induction by cancer chemopreventive agents' Chemico-Biological Interactions, vol. 133, no. 1-3, pp. 291-294. DOI:
10.1016/S0009-2797(00)00216-7

Research output: Contribution To Journal



Activities

UK patent for HRN mouse line

Role: Member
Activity: Types of Business and Community - Other

30 12 2005

Tayview Primary School

Role: Member
Activity: Types of Public engagement and outreach - Schools engagement

9 11 2017

Relay for Life - Dundee

Role: Participant
Activity: Types of Public engagement and outreach - Festival/Exhibition

24 9 2007

Relay for Life - Dundee

Role: Participant
Activity: Types of Public engagement and outreach - Festival/Exhibition

21 9 2008

Relay for Life - Dundee

Role: Presenter
Activity: Types of Public engagement and outreach - Festival/Exhibition

25 8 2012

Relay for Life - Blairgowrie

Role: Presenter
Activity: Types of Public engagement and outreach - Festival/Exhibition

7 8 2010

Relay for Life - Blairgowrie

Role: Presenter
Activity: Types of Public engagement and outreach - Festival/Exhibition

23 8 2008

Relay for Life - Arbroath

Role: Presenter
Activity: Types of Public engagement and outreach - Festival/Exhibition

19 9 2009

Relay for Life - Arbroath

Role: Presenter
Activity: Types of Public engagement and outreach - Festival/Exhibition

26 9 2010

Race for Life - Dundee

Role: Presenter
Activity: Types of Public engagement and outreach - Festival/Exhibition

14 6 2009

Race for Life - Dundee

Role: Presenter
Activity: Types of Public engagement and outreach - Festival/Exhibition

15 6 2008

Phd supervisor training

Role: Participant
Activity: Participation in workshop, seminar, course

17 10 2012

Open Door Dundee

Role: Participant
Activity: Festival/Exhibition

16 9 2017

Maggie's Centre visit

Role: Host
Activity: Types of Public engagement and outreach - Festival/Exhibition

10 6 2010

Maggie's Centre

Role: Presenter
Activity: Types of Public engagement and outreach - Public lecture/debate/seminar

4 2 2010

Langlands Primary School

Role: Member
Activity: Types of Public engagement and outreach - Schools engagement

11 5 2018

Lab Tour

Role: Host
Activity: Types of Public engagement and outreach - Festival/Exhibition

11 5 2010

Lab Tour

Role: Host
Activity: Types of Public engagement and outreach - Festival/Exhibition

17 2 2011

Lab Tour

Role: Host
Activity: Types of Public engagement and outreach - Festival/Exhibition

23 2 2010

Lab Tour

Role: Host
Activity: Types of Public engagement and outreach - Festival/Exhibition

6 5 2009