Christopher Barratt

+44 (0)1382 383398
Head of Division - Systems Medicine & Professor of Reproductive Medicine

Bio

Biography

Professor Barratt is Head of Division Systems Medicine, Head of the Reproductive Medicine Group at the University of Dundee as well as a clinical scientist (Hon) with NHS Tayside. He graduated with an Honours degree in Zoology and then completed a Post Graduate Certificate in Education (University of Wales, Swansea). His PhD, also in Zoology, was under the supervision of Jack Cohen at the University of Birmingham.

His formative post-doctoral studies and ART experience was gained at the University of Sheffield [with Ian Cooke] where they specialized in natural cycle IVF. From 1997-2005 he was the Scientific Director of the ART Centre at the Birmingham Women’s Hospital.

Professor Barratt has been awarded a number of honors for outstanding contributions to the discipline e.g. Young Andrologist of the Year (American Andrology Society), the Professor Sir Robert Edwards keynote lecture at ESHRE.

He is a regularly invited speaker at national and international scientific conferences/workshops. He was a member of the WHO Male Fertility Semen Analysis Taskforce (for both the 4th and 5th editions) and director of the WHO (2012-2017) Male Fertility Expert Working Group which devised a new system for the diagnosis and treatment of the infertile male  (https://academic.oup.com/humupd/article/23/6/660/3979420). He was a member of the Human Fertilisation and Embryology Authority for 6 years.

Professor Barratt has recently been appointed to editorial board of WHO for development of new Semen Analysis manual (6th edition).

He has been on the Editorial Board of Human Reproduction, Human Fertility, Biology of Reproduction, Human Reproduction Update, Journal of Andrology and is currently Editor-in-Chief of Molecular Human Reproduction (Impact factor 5 year 3.6)

 

His life’s ambition is to see - live - Wales comprehensively beat the All Blacks.

Research

We are primarily focused on understanding the function of the human spermatozoa and identifying the key factors in the process of sperm egg interation.

Our research uses cutting edge technology combined with selected samples from patients with well-defined pathology. As such the research has a very strong translational focus.

Our primary collaborators in Dundee are the IVF clinic at NHS Tayside, Abertay University's Dr Sean Brown, Professor Paul Wyatt (Drug Discovery Unit, SLS), and Paul Andrews (National Phenotypic Screening Centre, SLS http://npsc.ac.uk/)

We are funded by NHS Tayside, MRC, Chief Scientists Office (Scotland), Astra Zeneca and the Bill and Melinda Gates Foundation.

We regularly contribute to public debates on reproductive issues: e.g. impact of male age https://www.bionews.org.uk/page_135205

Patents

  • Inventor: Barratt C (CMDN) & Wyatt PG (CLS) ‘Stimulation of human sperm motility’. International application number: PCT/GB2012/052514. Publication number WO/2013/054111. Publication date 18th April 2013.
  • Inventor: Genosis & Barratt C ‘Method and detection kit for male infertility’ 1999. WO/99066331

Teaching

Professor Barratt has supervised 29 MSc, PhD, MD students almost all of whom work in in the field of reproductive medicine.

His teaching consists of:

Supervisor: 9 MSc/PhD students

Leader: SSC in Stem Cells and Assisted Conception

Leader: Human Reproduction, Assisted Conception and Embryonic Stem Cells BMSc

Leader: Human Clinical Embryology and Assisted Conception MSc.

 

External examiner (previous)

  • Quinquennial Review MSc for ART at University of Oxford (2014).
  • MSc for Reproductive and Developmental Biology at University of Edinburgh (2009-2013).
  • United Arab Emirates Ministry of Higher Education and Scientific Research (2012-2013).
  • 3rd year Reproductive Biology course at University of Edinburgh (2015-16).
  • Endocrine and Reproduction Course (MDSC 2101) University West Indies 2014-2017.
  • University of Nottingham (2004-2006).
  • MSc in Embryology at the University of Leeds (2002-2004).
  • MSc ART University of Bristol (2002-2005).

Publications

Homozygous in-frame deletion in CATSPERE in a man producing spermatozoa with loss of CatSper function and compromised fertilizing capacity
8/2018, Human Reproduction
Research Output: Contribution To Journal > Article

A Dolce & Gabbana model in every ART clinic?
7/2018, Molecular Human Reproduction
Research Output: Contribution To Journal > Editorial

Education, education, education : now more than ever?
6/2018, Molecular Human Reproduction
Research Output: Contribution To Journal > Article

Single-cell analysis of [Ca2+]i signalling in sub-fertile men : characteristics and relation to fertilization outcome
4/2018, Human Reproduction
Research Output: Contribution To Journal > Article

Protect us from poor-quality medical research
3/2018, Human Reproduction
Research Output: Contribution To Journal > Article

‘Man Up’ : the importance and strategy for placing male reproductive health centre stage in the political and research agenda.
1/2018, Human Reproduction
Research Output: Contribution To Journal > Article

People are very open-minded about new things, as long as they are exactly like the old ones
12/2017, Molecular Human Reproduction
Research Output: Contribution To Journal > Editorial

Complex CatSper-dependent and independent [Ca2+] signaling induced by human follicular fluid
7/2017, Human Reproduction
Research Output: Contribution To Journal > Article

The diagnosis of male infertility : an analysis of the evidence to support the developments of global WHO guidance. Challenges and future research opportunities
7/2017, Human Reproduction Update
Research Output: Contribution To Journal > Article

Current concepts and unresolved questions in human sperm cumulus and zona interaction
5/2017
Research Output: Contribution To Book Anthology > Chapter

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