Brian Lipworth

+44 (0)1382 383902
Professor of Allergy and Pulmonology (Clinical)

Bio

Research

SCOTTISH CENTRE FOR RESPIRATORY RESEARCH

This is a group which I set up with my own funding in 1991 which now enjoys an international reputation for research excellence in the field of clinical airway research. I have clinical and research expertise in respiratory and cardiovascular medicine, along with my original background in clinical pharmacology and therapeutics. This places me in a unique position in terms of my research profile, and particularly with respect to attracting peer reviewed and industry funding.

I have good collaborative relationships with several International pharmaceutical companies and with other universities in Europe and USA.  I have brought in 6.6 M in the last 5 years. I have signed up as commercial research champion with the Tayside Medical Science Centre and am now recruiting into numerous Pharmaceutical sponsored multicenter clinical trials.

To date, clinical research fellows under my supervision have resulted in 22 MD or PhD theses. I take my mentoring role of young fellows very seriously.

It gives me immense pride and satisfaction that three of my research fellows have been appointed to UK chairs – Nigel Wheeldon (Sheffield), David Kiely (Sheffield), Andrew Wilson (Norwich).

Research interests

Significance of Research for NHS

  • Research studies using using health informatics data linkage has identified a defined small airway asthma phenotype which is associated with impaired control (Manoharan et al Eur Respir J 2014; 44: 1353–1355; Lipworth et al Lancet RM 2014;2: 497–506;Jabbal et al J Allergy Clin Immunol 2016;138:601-603)
  • A genotyped database showed a adverse interaction between beta-2 receptor Arg16Gly genotype and use of long-acting beta-2 agonists (Lee et al. Br J Clin Pharmacol 2004:57:68-75, Palmer et al. Thorax 2006;61:940-44, Basu et al. J Allergy Clin Immunol 2009;124:1188-94; Turner et al J Allergy Clin Immunol 2016;138:107-113).  This led to the first RCT showing a personalised genotyped based approach to prescribing (Lipworth et al Clin Sci 2013;124:521-528) 
  • A meta-analysis evaluated potential adverse reactions to NSAIDs and COX2 inhibitors in patients with asthma (Morales et al J Allergy Clin Immunol 2014;134:40-45; Morales et al Allergy 2015;70:828-8) 
  • Health informatics demonstrated the potential for adverse effects of beta-blockers in asthma and concomitant cardiovascular disease (Morales et al BMC Medicine 2017;doi:10.1186/s12916-017-0781-0; Morales et al Br J Clin Pharmacol 2016;82:814-822; Morales et al Chest 2014;145:779-786) 
  • Using a national database, I also showed underuse of beta-blockers in patients with heart failure and COPD, indicating a clinically relevant unmet need in such patients (Lipworth et al Heart 2016;102:1909-1914).In addition I showed that beta-blockers are safe to use in COPD with any beta-2 receptor mediated adverse effects on lung function mitigated by concomitant  long acting muscarinic antagonists (Jabbal et al  QJM 2017;110:785-792) .This in turn led to an NIHR funded randomized  controlled trial  to evaluate the effects of bisoprolol on exacerbations in COPD on which I am co-chief applicant 
  • We showed the impact of the smoking ban on health in bar workers, and received international media coverage (Menzies et al JAMA 2006;296:1742-1748) with an accompanying editorial emphasizing its importance 
  • I have also shown that a novel osmotic bronchial challenge test with mannitol is well tolerated in primary care, to assess airway inflammation, resulting in better long term asthma control (Lipworth et al Chest 2010;141:607-15). A screening programme involving bronchial challenge testing was employed to identify potential overtreatment of patients with adult asthma in the community (Manoharan et al Clin Exp Allergy 2014;44:1240-1245) 
  • Research into the role of the unified allergic airway (Barnes et al Allergy 2007:62:73-80) and the role of  medical polypectomy (Vaidyanathan et al Ann Intern Med 2011;154:293-302)  has driven setting up of a unique one stop combined medical/surgical rhinology service

Teaching

Dundee Curriculum

I have played a major role in the implementation and development of the new medical curriculum in Dundee. In my capacity as system convener for respiratory teaching (1991-2014), I have been responsible for complete restructuring of the teaching delivered in this area, in which I have always had a significant hands on component. New innovations include the drawing up of an electronic study guide and web based teaching aids.

Postgraduate Teaching

I have previously been involved in teaching and examining for the MRCP PACES, Glasgow postgraduate respiratory medicine course; respiratory education for the Royal College of Physicians of Edinburgh. I also give regular postgraduate educational lectures to primary and secondary care doctors, both in the UK and abroad.

Publications

Kuo, CR, Jabbal, S & Lipworth, B 2018,

'Is small airways dysfunction related to asthma control and type 2 inflammation?' Annals of Allergy, Asthma & Immunology. DOI:
10.1016/j.anai.2018.08.009

Research output: Contribution To Journal



Lipworth, B, Jabbal, S & Kuo, CR 2018,

'Anti-interleukin 13 for asthma: stick or twist?' The Lancet Respiratory Medicine. DOI:
10.1016/S2213-2600(18)30275-3

Research output: Contribution To Journal



Lipworth, BJ & Jabbal, S 2018,

'What can we learn about COPD from impulse oscillometry?' Respiratory Medicine, vol. 139, pp. 106-109. DOI:
10.1016/j.rmed.2018.05.004

Research output: Contribution To Journal



Lipworth, B, Kuo, C & Jabbal, S 2018,

'Adrenal suppression with inhaled corticosteroids: the seed and the soil' The Lancet Respiratory Medicine, vol. 6, no. 6, pp. e19. DOI:
10.1016/S2213-2600(18)30148-6

Research output: Contribution To Journal



Weir-Mc Call, JR, Liu-Shiu-Cheong, PS, Struthers, AD, Lipworth, BJ & Houston, JG 2018,

'Disconnection of pulmonary and systemic arterial stiffness in COPD' International Journal of Chronic Obstructive Pulmonary Disease, vol. 13, pp. 1755-1765. DOI:
10.2147/COPD.S160077

Research output: Contribution To Journal



Jabbal, S & Lipworth, B 2018,

'Does the asthma visual analogue scale relate to the asthma control questionnaire?' Annals of Allergy, Asthma & Immunology. DOI:
10.1016/j.anai.2017.12.026

Research output: Contribution To Journal



Weir-Mc Call, JR, Liu Shiu Cheong, PSK, Struthers, AD, Lipworth, BJ & Houston, JG 2018,

'Pulmonary arterial stiffening in COPD and its implications for right ventricular remodelling.' European Radiology. DOI:
10.1007/s00330-018-5346-x

Research output: Contribution To Journal



Lipworth, B & Israel, E 2018,

'Asthma Step-Down Strategies: Perhaps the Patient Should Decide?' The Journal of Allergy and Clinical Immunology: In Practice, vol. 6, no. 2, pp. 644-645. DOI:
10.1016/j.jaip.2017.08.026

Research output: Contribution To Journal



Fathi, A, Weir-Mc Call, JR, Struthers, AD, Lipworth, BJ & Houston, JG 2018,

'Effects of contrast administration on cardiac MRI volumetric, flow and pulse wave velocity quantification using manual and software-based analysis' British Journal of Radiology, vol. 91, no. 1084, 20170717. DOI:
10.1259/bjr.20170717

Research output: Contribution To Journal



Jabbal, S & Lipworth, BJ 2017,

'Sensitivity of lung resistance and compliance to beta-blocker induced bronchoconstriction and long acting beta-agonist withdrawal in COPD' Lung. DOI:
10.1007/s00408-017-0079-1

Research output: Contribution To Journal



Jabbal, S, Anderson, W, Short, P, Morrison, A, Manoharan, A & Lipworth, BJ 2017,

'Cardiopulmonary interactions with beta-blockers and inhaled therapy in COPD' QJM : an International Journal of Medicine, vol. 110, no. 12, pp. 785-792. DOI:
10.1093/qjmed/hcx155

Research output: Contribution To Journal



Jabbal, S & Lipworth, BJ 2017,

'Blood eosinophils: The forgotten man of inhaled steroid dose titration ' Clinical and Experimental Allergy. DOI:
10.1111/cea.13057

Research output: Contribution To Journal



Lipworth, BJ & Jabbal, S 2017,

'Un-diagnosing persistent adult asthma' European Respiratory Journal, vol. 50, no. 5, 1701433. DOI:
10.1183/13993003.01433-2017

Research output: Contribution To Journal



Lipworth, BJ & Jabbal, S 2017,

'FULFIL: an Unmet Need in Chronic Obstructive Pulmonary Disease ' American Journal of Respiratory and Critical Care Medicine, vol. 196, no. 8, pp. 1082-1082. DOI:
10.1164/rccm.201704-0728LE

Research output: Contribution To Journal



Jabbal, S & Lipworth, BJ 2017,

'Tolerability of Bisoprolol on Domiciliary Spirometry in COPD' Lung. DOI:
10.1007/s00408-017-0061-y

Research output: Contribution To Journal



Lipworth, B & Jabbal, S 2017,

'A pragmatic approach to simplifying inhaler therapy for COPD' The Lancet Respiratory Medicine, vol. 5, no. 9, pp. 679-681. DOI:
10.1016/S2213-2600(17)30264-3

Research output: Contribution To Journal



Jabbal, S, Manoharan, A & Lipworth, BJ 2017,

'Bronchoprotective tolerance with indacaterol is not modified by concomitant tiotropium in persistent asthma' Clinical and Experimental Allergy, pp. 1-7. DOI:
10.1111/cea.12972

Research output: Contribution To Journal



Lipworth, BJ & Jabbal, S 2017,

'Drug-device interaction for systemic effects of fluticasone in patients with asthma' Annals of Allergy, Asthma & Immunology, vol. 119, no. 2, pp. 194. DOI:
10.1016/j.anai.2017.01.023

Research output: Contribution To Journal



Silkoff, PE, Flavin, S, Gordon, R, Loza, MJ, Sterk, PJ, Lutter, R, Diamant, Z, Turner, RB, Lipworth, BJ, Proud, D, Singh, D, Eich, A, Backer, V, Gern, JE, Herzmann, C, Halperin, SA, Mensinga, TT, Del Vecchio, AM, Branigan, P, San Mateo, L, Baribaud, F, Barnathan, ES & Johnston, SL 2017,

'TLR3 Blockade in Rhinovirus-Induced Experimental Asthma Exacerbations: A Randomized Controlled Study' Journal of Allergy and Clinical Immunology. DOI:
10.1016/j.jaci.2017.06.027

Research output: Contribution To Journal



Jabbal, S, Poli, G & Lipworth, B 2017,

'Does size really matter: relationship of particle size to lung deposition and exhaled fraction' Journal of Allergy and Clinical Immunology, vol. 139, no. 6, pp. 2013-2014.e1. DOI:
10.1016/j.jaci.2016.11.036

Research output: Contribution To Journal



Lipworth, BJ & Jabbal, S 2017,

'Reappraising the clinical impact of mepolizumab' Lancet, vol. 5, no. 6, e20. DOI:
10.1016/S2213-2600(17)30183-2

Research output: Contribution To Journal



Nair, A, Mc Kinlay, L, Williamson, P, Short, P, Burns, P & Lipworth, BJ 2017,

'Erratum to: Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers' European Journal of Clinical Pharmacology, vol. 73, no. 6, pp. 793-793. DOI:
10.1007/s00228-017-2259-6

Research output: Contribution To Journal



Galant, SP, Komarow, HD, Shin, H-W, Siddiqui, S & Lipworth, BJ 2017,

'The case for impulse oscillometry in the management of asthma in children and adults' Annals of Allergy, Asthma & Immunology, vol. 118, no. 6, pp. 664-671. DOI:
10.1016/j.anai.2017.04.009

Research output: Contribution To Journal



Lipworth, B & Jabbal, S 2017,

'Debate on long-acting β agonists for asthma: they think it's all over' The Lancet Respiratory Medicine, vol. 5, no. 3, pp. e14-e15. DOI:
10.1016/S2213-2600(17)30053-X

Research output: Contribution To Journal



Anderson, WJ, Short, P, Jabbal, S & Lipworth, B 2017,

'Inhaled corticosteroid dose-response in asthma: Should we measure inflammation?' Annals of Allergy, Asthma & Immunology, vol. 118, no. 2, pp. 179-185. DOI:
10.1016/j.anai.2016.11.018

Research output: Contribution To Journal



Morales, DR, Lipworth, BJ, Donnan, PT, Jackson, C & Guthrie, B 2017,

'Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study' BMC Medicine, vol. 15, 18. DOI:
10.1186/s12916-017-0781-0

Research output: Contribution To Journal



Anderson, W & Lipworth, B 2017,

'Obesity and asthma – do we need expensive therapies?' Thorax.

Research output: Contribution To Journal



Lipworth, B, Newton, J, Ram, B, Small, I & Schwarze, J 2017,

'An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel ' NPJ Primary Care Respiratory Medicine, vol. 27, 3, pp. 1-8. DOI:
10.1038/s41533-016-0001-y

Research output: Contribution To Journal



Lipworth, B & Jabbal, S 2017,

'Impact of Spacers on Therapeutic Ratio with Inhaled Corticosteroids' The Journal of Allergy and Clinical Immunology: In Practice, vol. 5, no. 4, pp. 1163. DOI:
10.1016/j.jaip.2017.03.011

Research output: Contribution To Journal



Bousquet, J, Hellings, PW, Agache, I, Bedbrook, A, Bachert, C, Bergmann, KC, Bewick, M, Bindslev-Jensen, C, Bosnic-Anticevitch, S, Bucca, C, Caimmi, DP, Camargos, PAM, Canonica, GW, Casale, T, Chavannes, NH, Cruz, AA, De Carlo, G, Dahl, R, Demoly, P, Devillier, P, Fonseca, J, Fokkens, WJ, Guldemond, NA, Haahtela, T, Illario, M, Just, J, Keil, T, Klimek, L, Kuna, P, Larenas-Linnemann, D, Morais-Almeida, M, Mullol, J, Murray, R, Naclerio, R, O'Hehir, RE, Papadopoulos, NG, Pawankar, R, Potter, P, Ryan, D, Samolinski, B, Schunemann, HJ, Sheikh, A, Simons, FER, Stellato, C, Todo-Bom, A, Tomazic, PV, Valiulis, A, Valovirta, E, Ventura, MT, Wickman, M, Young, I, Yorgancioglu, A, Zuberbier, T, Aberer, W, Akdis, CA, Akdis, M, Annesi-Maesano, I, Ankri, J, Ansotegui, IJ, Anto, JM, Arnavielhe, S, Asarnoj, A, Arshad, H, Avolio, F, Baiardini, I, Barbara, C, Barbagallo, M, Bateman, ED, Beghé, B, Bel, EH, Bennoor, KS, Benson, M, Białoszewski, AZ, Bieber, T, Bjermer, L, Blain, H, Blasi, F, Boner, AL, Bonini, M, Bonini, S, Bosse, I, Bouchard, J, Boulet, LP, Bourret, R, Bousquet, PJ, Braido, F, Briggs, AH, Brightling, CE, Brozek, J, Buhl, R, Bunu, C, Burte, E, Bush, A, Caballero-Fonseca, F, Calderon, MA, Camuzat, T, Cardona, V, Carreiro-Martins, P, Carriazo, AM, Carlsen, KH, Carr, W, Cepeda Sarabia, AM, Cesari, M, Chatzi, L, Chiron, R, Chivato, T, Chkhartishvili, E, Chuchalin, AG, Chung, KF, Ciprandi, G, de Sousa, JC, Cox, L, Crooks, G, Custovic, A, Dahlen, SE, Darsow, U, Dedeu, T, Deleanu, D, Denburg, JA, De Vries, G, Didier, A, Dinh-Xuan, AT, Dokic, D, Douagui, H, Dray, G, Dubakiene, R, Durham, SR, Du Toit, G, Dykewicz, MS, Eklund, P, El-Gamal, Y, Ellers, E, Emuzyte, R, Farrell, J, Fink Wagner, A, Fiocchi, A, Fletcher, M, Forastiere, F, Gaga, M, Gamkrelidze, A, Gemicioğlu, B, Gereda, JE, van Wick, RG, González Diaz, S, Grisle, I, Grouse, L, Gutter, Z, Guzmán, MA, Hellquist-Dahl, B, Heinrich, J, Horak, F, Hourihane, JOB, Humbert, M, Hyland, M, Iaccarino, G, Jares, EJ, Jeandel, C, Johnston, SL, Joos, G, Jonquet, O, Jung, KS, Jutel, M, Kaidashev, I, Khaitov, M, Kalayci, O, Kalyoncu, AF, Kardas, P, Keith, PK, Kerkhof, M, Kerstjens, HAM, Khaltaev, N, Kogevinas, M, Kolek, V, Koppelman, GH, Kowalski, ML, Kuitunen, M, Kull, I, Kvedariene, V, Lambrecht, B, Lau, S, Laune, D, Le, LTT, Lieberman, P, Lipworth, B, Li, J, Lodrup Carlsen, KC, Louis, R, Lupinek, C, Mac Nee, W, Magar, Y, Magnan, A, Mahboub, B, Maier, D, Majer, I, Malva, J, Manning, P, De Manuel Keenoy, E, Marshall, GD, Masjedi, MR, Mathieu-Dupas, E, Maurer, M, Mavale-Manuel, S, Melén, E, Melo-Gomes, E, Meltzer, EO, Mercier, J, Merk, H, Miculinic, N, Mihaltan, F, Milenkovic, B, Millot-Keurinck, J, Mohammad, Y, Momas, I, Mösges, R, Muraro, A, Namazova-Baranova, L, Nadif, R, Neffen, H, Nekam, K, Nieto, A, Niggemann, B, Nogueira-Silva, L, Nogues, M, Nyembue, TD, Ohta, K, Okamoto, Y, Okubo, K, Olive-Elias, M, Ouedraogo, S, Paggiaro, P, Pali-Schöll, I, Palkonen, S, Panzner, P, Papi, A, Park, HS, Passalacqua, G, Pedersen, S, Pereira, AM, Pfaar, O, Picard, R, Pigearias, B, Pin, I, Plavec, D, Pohl, W, Popov, TA, Portejoie, F, Postma, D, Poulsen, LK, Price, D, Rabe, KF, Raciborski, F, Roberts, G, Robalo-Cordeiro, C, Rodenas, F, Rodriguez-Mañas, L, Rolland, C, Roman Rodriguez, M, Romano, A, Rosado-Pinto, J, Rosario, N, Rottem, M, Sanchez-Borges, M, Sastre-Dominguez, J, Scadding, GK, Scichilone, N, Schmid-Grendelmeier, P, Serrano, E, Shields, M, Siroux, V, Sisul, JC, Skrindo, I, Smit, HA, Solé, D, Sooronbaev, T, Spranger, O, Stelmach, R, Sterk, PJ, Strandberg, T, Sunyer, J, Thijs, C, Triggiani, M, Valenta, R, Valero, A, van Eerd, M, van Ganse, E, van Hague, M, Vandenplas, O, Varona, LL, Vellas, B, Vezzani, G, Vazankari, T, Viegi, G, Vontetsianos, T, Wagenmann, M, Walker, S, Wang, DY, Wahn, U, Werfel, T, Whalley, B, Williams, DM, Williams, S, Wilson, N, Wright, J, Yawn, BP, Yiallouros, PK, Yusuf, OM, Zaidi, A, Zar, HJ, Zernotti, ME, Zhang, L, Zhong, N & Zidarn, M 2016,

'ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle' Clinical and Translational Allergy, vol. 6, 47, pp. 1-14. DOI:
10.1186/s13601-016-0137-4

Research output: Contribution To Journal



Brixner, D, Meltzer, EO, Marland, K, Carroll, CA, Munzel, U & Lipworth, B 2016,

'Implication of alternative minimal clinically important difference threshold estimation on technology assessment' International Journal of Technology Assessment in Health Care, vol. 32, no. 6, pp. 371-375. DOI:
10.1017/S0266462316000593

Research output: Contribution To Journal



Lipworth, B, Skinner, D, Devereux, G, Thomas, V, Ling Zhi Jie, J, Martin, J, Carter, V & Price, DB 2016,

'Underuse of β-blockers in heart failure and chronic obstructive pulmonary disease' Heart, vol. 102, no. 23, pp. 1909-1914. DOI:
10.1136/heartjnl-2016-309458

Research output: Contribution To Journal



Lipworth, B, Skinner, D, Devereux, G, Thomas, V, Ling Zhi Jie, J, Martin, J, Carter, V & Price, DB 2016,

'It is important to distinguish between HFr EF and HFp EF when interpreting these data' Heart (British Cardiac Society), vol. 102, no. 23, 1934. DOI:
10.1136/heartjnl-2016-310557

Research output: Contribution To Journal



Edwards, SC, Fairbrother, SE, Scowcroft, A, Chiu, G, Ternouth, A & Lipworth, BJ 2016,

'The burden of chronic obstructive pulmonary disease associated with maintenance monotherapy in the UK' International Journal of Chronic Obstructive Pulmonary Disease, vol. 11, no. 1, pp. 2851-2858. DOI:
10.2147/COPD.S109707

Research output: Contribution To Journal



Jabbal, S, Manoharan, A, Anderson, W & Lipworth, B 2016,

'LATE-BREAKING ABSTRACT: Real life impact of long acting beta-2-agonist withdrawal in controlled step 3 asthma patients' European Respiratory Journal, vol. 48, no. Suppl60. DOI:
10.1183/13993003.congress-2016.OA4829

Research output: Contribution To Journal



Weir-Mc Call, JR, Kamalasanan, A, Cassidy, DB, Struthers, AD, Lipworth, BJ & Houston, JG 2016,

'Assessment of proximal pulmonary arterial stiffness using magnetic resonance imaging: effects of technique, age and exercise' BMJ Open Respiratory Research, vol. 3, no. 1, e000149. DOI:
10.1136/bmjresp-2016-000149

Research output: Contribution To Journal



Jabbal, S, Manoharan, A, Anderson, W, Lipworth, J & Lipworth, B 2016,

'Real-life effect of long-acting β2-agonist withdrawal in patients with controlled step 3 asthma' Annals of Allergy, Asthma & Immunology, vol. 117, no. 4, pp. 430-431. DOI:
10.1016/j.anai.2016.07.022

Research output: Contribution To Journal



Lipworth, B, Wedzicha, J, Devereux, G, Vestbo, J & Dransfield, MT 2016,

'Beta-blockers in COPD: time for reappraisal' European Respiratory Journal, vol. 48, no. 3, pp. 880-888. DOI:
10.1183/13993003.01847-2015

Research output: Contribution To Journal



Morales, DR, Dreischulte, T, Lipworth, BJ, Donnan, PT, Jackson, C & Guthrie, B 2016,

'Respiratory effect of beta-blocker eye drops in asthma: population-based study and meta-analysis of clinical trials' British Journal of Clinical Pharmacology, vol. 82, no. 3, pp. 814-822. DOI:
10.1111/bcp.13006

Research output: Contribution To Journal



Jabbal, S, Manoharan, A, Lipworth, J & Lipworth, B 2016,

'Utility of impulse oscillometry in patients with moderate to severe persistent asthma' Journal of Allergy and Clinical Immunology, vol. 138, no. 2, pp. 601-603. DOI:
10.1016/j.jaci.2015.12.1336

Research output: Contribution To Journal



Lipworth, B 2016,

'Improvements with sublingual house dust mite immunotherapy in allergic rhinitis' Journal of Allergy and Clinical Immunology, vol. 138, no. 2, pp. 634-635. DOI:
10.1016/j.jaci.2016.03.033

Research output: Contribution To Journal



Currie , GP & Lipworth, BJ 2016,

'Inhaled treatment for chronic obstructive pulmonary disease: what’s new and how does it fit? ' QJM : an International Journal of Medicine, vol. 109, no. 8, pp. 505-512. DOI:
10.1093/qjmed/hcv212

Research output: Contribution To Journal



Bousquet, J, Farrell, J, Crooks, G, Hellings, P, Bel, EH, Bewick, M, Chavannes, NH, de Sousa, JC, Cruz, AA, Haahtela, T, Joos, G, Khaltaev, N, Malva, J, Muraro, A, Nogues, M, Palkonen, S, Pedersen, S, Robalo-Cordeiro, C, Samolinski, B, Strandberg, T, Valiulis, A, Yorgancioglu, A, Zuberbier, T, Bedbrook, A, Aberer, W, Adachi, M, Agusti, A, Akdis, CA, Akdis, M, Ankri, J, Alonso, A, Annesi-Maesano, I, Ansotegui, IJ, Anto, JM, Arnavielhe, S, Arshad, H, Bai, C, Baiardini, I, Bachert, C, Baigenzhin, AK, Barbara, C, Bateman, ED, Beghé, B, Kheder, AB, Bennoor, KS, Benson, M, Bergmann, KC, Bieber, T, Bindslev-Jensen, C, Bjermer, L, Blain, H, Blasi, F, Boner, AL, Bonini, M, Bonini, S, Bosnic-Anticevitch, S, Boulet, LP, Bourret, R, Bousquet, PJ, Braido, F, Briggs, AH, Brightling, CE, Brozek, J, Buhl, R, Burney, PG, Bush, A, Caballero-Fonseca, F, Caimmi, D, Calderon, MA, Calverley, PM, Camargos, PAM, Canonica, GW, Camuzat, T, Carlsen, KH, Carr, W, Carriazo, A, Casale, T, Cepeda Sarabia, AM, Chatzi, L, Chen, YZ, Chiron, R, Chkhartishvili, E, Chuchalin, AG, Chung, KF, Ciprandi, G, Cirule, I, Cox, L, Costa, DJ, Custovic, A, Dahl, R, Dahlen, SE, Darsow, U, De Carlo, G, De Blay, F, Dedeu, T, Deleanu, D, De Manuel Keenoy, E, Demoly, P, Denburg, JA, Devillier, P, Didier, A, Dinh-Xuan, AT, Djukanovic, R, Dokic, D, Douagui, H, Dray, G, Dubakiene, R, Durham, SR, Dykewicz, MS, El-Gamal, Y, Emuzyte, R, Fabbri, LM, Fletcher, M, Fiocchi, A, Fink Wagner, A, Fonseca, J, Fokkens, WJ, Forastiere, F, Frith, P, Gaga, M, Gamkrelidze, A, Garces, J, Garcia-Aymerich, J, Gemicioğlu, B, Gereda, JE, González Diaz, S, Gotua, M, Grisle, I, Grouse, L, Gutter, Z, Guzmán, MA, Heaney, LG, Hellquist-Dahl, B, Henderson, D, Hendry, A, Heinrich, J, Heve, D, Horak, F, Hourihane, JOB, Howarth, P, Humbert, M, Hyland, ME, Illario, M, Ivancevich, JC, Jardim, JR, Jares, EJ, Jeandel, C, Jenkins, C, Johnston, SL, Jonquet, O, Julge, K, Jung, KS, Just, J, Kaidashev, I, Khaitov, MR, Kalayci, O, Kalyoncu, AF, Keil, T, Keith, PK, Klimek, L, Koffi N'Goran, B, Kolek, V, Koppelman, GH, Kowalski, ML, Kull, I, Kuna, P, Kvedariene, V, Lambrecht, B, Lau, S, Larenas-Linnemann, D, Laune, D, Le, LTT, Lieberman, P, Lipworth, B, Li, J, Lodrup Carlsen, K, Louis, R, Mac Nee, W, Magard, Y, Magnan, A, Mahboub, B, Mair, A, Majer, I, Makela, MJ, Manning, P, Mara, S, Marshall, GD, Masjedi, MR, Matignon, P, Maurer, M, Mavale-Manuel, S, Melén, E, Melo-Gomes, E, Meltzer, EO, Menzies-Gow, A, Merk, H, Michel, JP, Miculinic, N, Mihaltan, F, Milenkovic, B, Mohammad, GMY, Molimard, M, Momas, I, Montilla-Santana, A, Morais-Almeida, M, Morgan, M, Mösges, R, Mullol, J, Nafti, S, Namazova-Baranova, L, Naclerio, R, Neou, A, Neffen, H, Nekam, K, Niggemann, B, Ninot, G, Nyembue, TD, O'Hehir, RE, Ohta, K, Okamoto, Y, Okubo, K, Ouedraogo, S, Paggiaro, P, Pali-Schöll, I, Panzner, P, Papadopoulos, N, Papi, A, Park, HS, Passalacqua, G, Pavord, I, Pawankar, R, Pengelly, R, Pfaar, O, Picard, R, Pigearias, B, Pin, I, Plavec, D, Poethig, D, Pohl, W, Popov, TA, Portejoie, F, Potter, P, Postma, D, Price, D, Rabe, KF, Raciborski, F, Radier Pontal, F, Repka-Ramirez, S, Reitamo, S, Rennard, S, Rodenas, F, Roberts, J, Roca, J, Rodriguez Mañas, L, Rolland, C, Roman Rodriguez, M, Romano, A, Rosado-Pinto, J, Rosario, N, Rosenwasser, L, Rottem, M, Ryan, D, Sanchez-Borges, M, Scadding, GK, Schunemann, HJ, Serrano, E, Schmid-Grendelmeier, P, Schulz, H, Sheikh, A, Shields, M, Siafakas, N, Sibille, Y, Similowski, T, Simons, FER, Sisul, JC, Skrindo, I, Smit, HA, Solé, D, Sooronbaev, T, Spranger, O, Stelmach, R, Sterk, PJ, Sunyer, J, Thijs, C, To, T, Todo-Bom, A, Triggiani, M, Valenta, R, Valero, AL, Valia, E, Valovirta, E, Van Ganse, E, van Hage, M, Vandenplas, O, Vasankari, T, Vellas, B, Vestbo, J, Vezzani, G, Vichyanond, P, Viegi, G, Vogelmeier, C, Vontetsianos, T, Wagenmann, M, Wallaert, B, Walker, S, Wang, DY, Wahn, U, Wickman, M, Williams, DM, Williams, S, Wright, J, Yawn, BP, Yiallouros, PK, Yusuf, OM, Zaidi, A, Zar, HJ, Zernotti, ME, Zhang, L, Zhong, N, Zidarn, M & Mercier, J 2016,

'Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)' Clinical and Translational Allergy, vol. 6, 29, pp. 1-18. DOI:
10.1186/s13601-016-0116-9

Research output: Contribution To Journal



Turner, S, Francis, B, Vijverberg, S, Pino-Yanes, M, Maitland-van der Zee, AH, Basu, K, Bignell, L, Mukhopadhyay, S, Tavendale, R, Palmer, C, Hawcutt, D, Pirmohamed, M, Burchard, EG & Lipworth, B 2016,

'Childhood asthma exacerbations and the Arg16 β2-receptor polymorphism: A meta-analysis stratified by treatment' Journal of Allergy and Clinical Immunology, vol. 138, no. 1, pp. 107-113. DOI:
10.1016/j.jaci.2015.10.045

Research output: Contribution To Journal



Manoharan, A, Morrison, AE & Lipworth, BJ 2016,

'Effects of the inverse alpha-agonist doxazosin in allergic rhinitis' Clinical and Experimental Allergy, vol. 46, no. 5, pp. 696-704. DOI:
10.1111/cea.12700

Research output: Contribution To Journal



Weir-Mc Call, JR, Struthers, AD, Lipworth, BJ & Houston, JG 2016,

'Comparing pace and speed in the pulmonary circulation?' American Journal of Physiology: Heart and Circulatory Physiology, vol. 310, no. 7, H949. DOI:
10.1152/ajpheart.00065.2016

Research output: Contribution To Journal



Manoharan, A, Morrison, AE & Lipworth, B 2016,

'Effects of adding Tiotropium or Aclidinium as triple therapy using impulse oscillometry in COPD' Lung, vol. 194, no. 2, pp. 259-266. DOI:
10.1007/s00408-015-9839-y

Research output: Contribution To Journal



Jabbal, S, Manoharan, A, Lipworth, J, Anderson, W, Short, P & Lipworth, B 2016,

'Is Gly16Arg β2 Receptor Polymorphism Related to Impulse Oscillometry in a Real-Life Asthma Clinic Setting?' Lung, vol. 194, no. 2, pp. 267-271. DOI:
10.1007/s00408-016-9848-5

Research output: Contribution To Journal



Manoharan, A, von Wilamowitz-Moellendorff, A, Morrison, A & Lipworth, BJ 2016,

'Effects of formoterol or salmeterol on impulse oscillometry in persistent asthma' Journal of Allergy and Clinical Immunology, vol. 137, no. 3, pp. 727-733.e1. DOI:
10.1016/j.jaci.2015.06.012

Research output: Contribution To Journal



Lipworth, B & Jabbal, S 2016,

'Of mice and men-the curious tale of β blockers in asthma' The Lancet Respiratory Medicine, vol. 4, no. 2, pp. 89-91. DOI:
10.1016/S2213-2600(16)00011-4

Research output: Contribution To Journal



Lipworth, B, Jabbal, S, Manoharan, A, Anderson, W & Short, P 2016,

'Inhaled corticosteroid dose-response on blood eosinophils in asthma' The Lancet Respiratory Medicine, vol. 4, no. 1, pp. e1. DOI:
10.1016/S2213-2600(15)00504-4

Research output: Contribution To Journal



Lipworth, BJ, Anderson, WJ & Short, PM 2016,

'From mouse to man: predicting biased effects of beta-blockers in asthma' British Journal of Pharmacology, vol. 173, no. 1, pp. 248-249. DOI:
10.1111/bph.13335

Research output: Contribution To Journal



Bousquet, J, Schunemann, HJ, Fonseca, J, Samolinski, B, Bachert, C, Canonica, GW, Casale, T, Cruz, AA, Demoly, P, Hellings, P, Valiulis, A, Wickman, M, Zuberbier, T, Bosnic-Anticevitch, S, Bedbrook, A, Bergmann, KC, Caimmi, D, Dahl, R, Fokkens, WJ, Grisle, I, Lodrup Carlsen, K, Mullol, J, Muraro, A, Palkonen, S, Papadopoulos, N, Passalacqua, G, Ryan, D, Valovirta, E, Yorgancioglu, A, Aberer, W, Agache, I, Adachi, M, Akdis, CA, Akdis, M, Annesi-Maesano, I, Ansotegui, IJ, Anto, JM, Arnavielhe, S, Arshad, H, Baiardini, I, Baigenzhin, AK, Barbara, C, Bateman, ED, Beghé, B, Bel, EH, Ben Kheder, A, Bennoor, KS, Benson, M, Bewick, M, Bieber, T, Bindslev-Jensen, C, Bjermer, L, Blain, H, Boner, AL, Boulet, LP, Bonini, M, Bonini, S, Bosse, I, Bourret, R, Bousquet, PJ, Braido, F, Briggs, AH, Brightling, CE, Brozek, J, Buhl, R, Burney, PG, Bush, A, Caballero-Fonseca, F, Calderon, MA, Camargos, PAM, Camuzat, T, Carlsen, KH, Carr, W, Cepeda Sarabia, AM, Chavannes, NH, Chatzi, L, Chen, YZ, Chiron, R, Chkhartishvili, E, Chuchalin, AG, Ciprandi, G, Cirule, I, Correia De Sousa, J, Cox, L, Crooks, G, Costa, DJ, Custovic, A, Dahlen, SE, Darsow, U, De Carlo, G, De Blay, F, Dedeu, T, Deleanu, D, Denburg, JA, Devillier, P, Didier, A, Dinh-Xuan, AT, Dokic, D, Douagui, H, Dray, G, Dubakiene, R, Durham, SR, Dykewicz, MS, El-Gamal, Y, Emuzyte, R, Fink Wagner, A, Fletcher, M, Fiocchi, A, Forastiere, F, Gamkrelidze, A, Gemicioʇlu, B, Gereda, JE, González Diaz, S, Gotua, M, Grouse, L, Guzmán, MA, Haahtela, T, Hellquist-Dahl, B, Heinrich, J, Horak, F, Hourihane, JOB, Howarth, P, Humbert, M, Hyland, ME, Ivancevich, JC, Jares, EJ, Johnston, SL, Joos, G, Jonquet, O, Jung, KS, Just, J, Kaidashev, I, Kalayci, O, Kalyoncu, AF, Keil, T, Keith, PK, Khaltaev, N, Klimek, L, Koffi N'Goran, B, Kolek, V, Koppelman, GH, Kowalski, ML, Kull, I, Kuna, P, Kvedariene, V, Lambrecht, B, Lau, S, Larenas-Linnemann, D, Laune, D, Le, LTT, Lieberman, P, Lipworth, B, Li, J, Louis, R, Magard, Y, Magnan, A, Mahboub, B, Majer, I, Makela, MJ, Manning, P, De Manuel Keenoy, E, Marshall, GD, Masjedi, MR, Maurer, M, Mavale-Manuel, S, Melén, E, Melo-Gomes, E, Meltzer, EO, Merk, H, Miculinic, N, Mihaltan, F, Milenkovic, B, Mohammad, Y, Molimard, M, Momas, I, Montilla-Santana, A, Morais-Almeida, M, Mösges, R, Namazova-Baranova, L, Naclerio, R, Neou, A, Neffen, H, Nekam, K, Niggemann, B, Nyembue, TD, O'Hehir, RE, Ohta, K, Okamoto, Y, Okubo, K, Ouedraogo, S, Paggiaro, P, Pali-Schöll, I, Palmer, S, Panzner, P, Papi, A, Park, HS, Pavord, I, Pawankar, R, Pfaar, O, Picard, R, Pigearias, B, Pin, I, Plavec, D, Pohl, W, Popov, TA, Portejoie, F, Postma, D, Potter, P, Price, D, Rabe, KF, Raciborski, F, Radier Pontal, F, Repka-Ramirez, S, Robalo-Cordeiro, C, Rolland, C, Rosado-Pinto, J, Reitamo, S, Rodenas, F, Roman Rodriguez, M, Romano, A, Rosario, N, Rosenwasser, L, Rottem, M, Sanchez-Borges, M, Scadding, GK, Serrano, E, Schmid-Grendelmeier, P, Sheikh, A, Simons, FER, Sisul, JC, Skrindo, I, Smit, HA, Solé, D, Sooronbaev, T, Spranger, O, Stelmach, R, Strandberg, T, Sunyer, J, Thijs, C, Todo-Bom, A, Triggiani, M, Valenta, R, Valero, AL, Van Hage, M, Vandenplas, O, Vezzani, G, Vichyanond, P, Viegi, G, Wagenmann, M, Walker, S, Wang, DY, Wahn, U, Williams, DM, Wright, J, Yawn, BP, Yiallouros, PK, Yusuf, OM, Zar, HJ, Zernotti, ME, Zhang, L, Zhong, N, Zidarn, M & Mercier, J 2015,

'MACVIA-ARIA Sentinel Networ K for allergic rhinitis (MASK-rhinitis): The new generation guideline implementation' Allergy, vol. 70, no. 11, pp. 1372-1392. DOI:
10.1111/all.12686

Research output: Contribution To Journal



Weir-Mc Call, JR, Struthers, AD, Lipworth, BJ & Houston, JG 2015,

'The role of pulmonary arterial stiffness in COPD' Respiratory Medicine, vol. 109, no. 11, pp. 1381-1390. DOI:
10.1016/j.rmed.2015.06.005

Research output: Contribution To Journal



Short, PM, Anderson, WJ, Elder, DHJ, Struthers, AD & Lipworth, BJ 2015,

'Impact of left ventricular hypertrophy on survival in chronic obstructive pulmonary disease' Lung, vol. 193, no. 4, pp. 487-495. DOI:
10.1007/s00408-015-9724-8

Research output: Contribution To Journal



Lipworth, BJ 2015,

'Biomarkers to predict inhaled corticosteroid response' Journal of Allergy and Clinical Immunology, vol. 136, no. 2, pp. 515. DOI:
10.1016/j.jaci.2015.04.037

Research output: Contribution To Journal



Morales, DR, Guthrie, B, Lipworth, BJ, Jackson, C, Donnan, PT & Santiago, VH 2015,

'NSAID exacerbated respiratory disease: a meta-analysis evaluating prevalence, mean provocative dose of aspirin and increased asthma morbidity' Allergy, vol. 70, no. 7, pp. 828-835. DOI:
10.1111/all.12629

Research output: Contribution To Journal



Lipworth, B 2015,

'Nasal endoscopy to characterize sinonasal disease' Journal of Allergy and Clinical Immunology, vol. 136, no. 1, pp. 212. DOI:
10.1016/j.jaci.2015.04.004

Research output: Contribution To Journal



Short, PM, Anderson, WJ, Manoharan, A & Lipworth, BJ 2015,

'Usefulness of impulse oscillometry for the assessment of airway hyperresponsiveness in mild-to-moderate adult asthma' Annals of Allergy, Asthma & Immunology, vol. 115, no. 1, pp. 17-20. DOI:
10.1016/j.anai.2015.04.022

Research output: Contribution To Journal



Manoharan, A, Griffin, B, Lipworth, J, Berg, J, Andrew, N, Jackson, C & Lipworth, B 2015,

'β2-Adrenergic receptor Gly16Arg polymorphism and impaired asthma control in corticosteroid-treated asthmatic adults' Annals of Allergy, Asthma & Immunology, vol. 114, no. 5, pp. 421-423. DOI:
10.1016/j.anai.2015.01.017

Research output: Contribution To Journal



Lipworth, B 2015,

'Tiotropium in asthma' The Lancet Respiratory Medicine, vol. 3, no. 5, pp. e16-e17. DOI:
10.1016/S2213-2600(15)00104-6

Research output: Contribution To Journal



Manoharan, A, Anderson, WJ, Lipworth, J & Lipworth, BJ 2015,

'Assessment of spirometry and impulse oscillometry in relation to asthma control' Lung, vol. 193, no. 1, pp. 47-51. DOI:
10.1007/s00408-014-9674-6

Research output: Contribution To Journal



Lipworth, B 2015,

'Clinical relevance of house dust mite immunotherapy' Journal of Allergy and Clinical Immunology, vol. 135, no. 1, pp. 288-288. DOI:
10.1016/j.jaci.2014.09.020

Research output: Contribution To Journal



Anderson, WJ, Short, PM, Williamson, PA, Manoharan, A & Lipworth, BJ 2014,

'The inverse agonist propranolol confers no corticosteroid-sparing activity in mild-to-moderate persistent asthma' Clinical Science, vol. 127, no. 11, pp. 635-643. DOI:
10.1042/CS20140249

Research output: Contribution To Journal



Manoharan, A, Anderson, WJ, Lipworth, J, Ibrahim, I & Lipworth, BJ 2014,

'Small airway dysfunction is associated with poorer asthma control' European Respiratory Journal, vol. 44, no. 5, pp. 1353-1355. DOI:
10.1183/09031936.00082314

Research output: Contribution To Journal



Manoharan, A, Short, PM, Anderson, WJ & Lipworth, BJ 2014,

'Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study' Lung, vol. 192, no. 5, pp. 649-652. DOI:
10.1007/s00408-014-9611-8

Research output: Contribution To Journal



Manoharan, A, Lipworth, B, Craig, E & Jackson, C 2014,

'The potential role of direct and indirect bronchial challenge testing to identify overtreatment of community managed asthma' Clinical and Experimental Allergy, vol. 44, no. 10, pp. 1240-1245. DOI:
10.1111/cea.12352

Research output: Contribution To Journal



Morales, DR, Lipworth, BJ, Guthrie, B, Jackson, C, Donnan, PT & Santiago, VH 2014,

'Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: meta-analysis of controlled clinical trials' Journal of Allergy and Clinical Immunology, vol. 134, no. 1, pp. 40-45.e10. DOI:
10.1016/j.jaci.2013.10.057

Research output: Contribution To Journal



Lipworth, BJ 2014,

'Adrenal suppression with mometasone furoate/formoterol' CHEST, vol. 145, no. 5, pp. 1175-1176. DOI:
10.1378/chest.14-0143

Research output: Contribution To Journal



Morales, DR, Jackson, C, Lipworth, BJ, Donnan, PT & Guthrie, B 2014,

'Adverse respiratory effect of acute beta-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials' CHEST, vol. 145, no. 4, pp. 779-786. DOI:
10.1378/chest.13-1235

Research output: Contribution To Journal



Lipworth, BJ 2014,

'Lack of clinically relevant differences between combination therapy and monotherapy in COPD' European Respiratory Journal, vol. 43, no. 4, pp. 1204. DOI:
10.1183/09031936.00143513

Research output: Contribution To Journal



Goudie, AR, Lipworth, BJ, Hopkinson, PJ, Wei, L & Struthers, AD 2014,

'Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial' The Lancet Respiratory Medicine, vol. 2, no. 4, pp. 293-300. DOI:
10.1016/S2213-2600(14)70013-X

Research output: Contribution To Journal



Lipworth, B, Short, P, Anderson, W & Williamson, P 2014,

'Reply: pharmacological obfuscation of clinical relevance' American Journal of Respiratory and Critical Care Medicine, vol. 189, no. 3, pp. 360-361. DOI:
10.1164/rccm.201306-1166LE

Research output: Contribution To Journal



Short, PM, Anderson, WJ, Williamson, PA & Lipworth, BJ 2014,

'Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids' Heart (British Cardiac Society), vol. 100, no. 3, pp. 219-223. DOI:
10.1136/heartjnl-2013-304769

Research output: Contribution To Journal



Anderson, WJ, Short, PM, Williamson, PA, Morrison, AE, Palmer, C, Tavendale, R & Lipworth, BJ 2014,

'Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients' Clinical Science, vol. 126, no. 1, pp. 75-83. DOI:
10.1042/CS20130213

Research output: Contribution To Journal



Lipworth, BJ 2014,

'Emerging role of long acting muscarinic antagonists for asthma' British Journal of Clinical Pharmacology, vol. 77, no. 1, pp. 55-62. DOI:
10.1111/bcp.12123

Research output: Contribution To Journal



Anderson, WJ, Short, PM, Manoharan, A, Lipworth, JLR & Lipworth, BJ 2014,

'Influence of β2-adrenoceptor 16 genotype on propranolol-induced bronchoconstriction in patients with persistent asthma' Annals of Allergy, Asthma & Immunology, vol. 112, no. 5, pp. 475-476. DOI:
10.1016/j.anai.2014.02.016

Research output: Contribution To Journal



Lipworth, B, Manoharan, A & Anderson, W 2014,

'Unlocking the quiet zone: the small airway asthma phenotype' The Lancet Respiratory Medicine, vol. 2, no. 6, pp. 497-506. DOI:
10.1016/S2213-2600(14)70103-1

Research output: Contribution To Journal



Lipworth, B 2013,

'β-Adrenoceptor genotype and bronchoprotective subsensitivity with long-acting β-agonists in asthma' American Journal of Respiratory and Critical Care Medicine, vol. 188, no. 12, pp. 1386-1387. DOI:
10.1164/rccm.201311-1968ED

Research output: Contribution To Journal



Lipworth, B 2013,

'Systemic safety of fluticasone furoate/vilanterol combination' Thorax, vol. 68, no. 12, pp. 1165. DOI:
10.1136/thoraxjnl-2013-203910

Research output: Contribution To Journal



Lipworth, B 2013,

'Uncorrected nitric oxide levels in mild asthmatics produce flawed interpretation' Journal of Allergy and Clinical Immunology, vol. 132, no. 5, pp. 1255. DOI:
10.1016/j.jaci.2013.07.043

Research output: Contribution To Journal



Lipworth, B, Manoharan, A & Short, P 2013,

'Adverse effects of long-acting Beta-agonists on airway hyperresponsiveness' American Journal of Respiratory Cell and Molecular Biology, vol. 49, no. 3, pp. 501-502. DOI:
10.1165/rcmb.2013-0139LE

Research output: Contribution To Journal



Lipworth, B 2013,

'Author response' Annals of Allergy, Asthma & Immunology, vol. 111, no. 3, pp. 234. DOI:
10.1016/j.anai.2013.06.029

Research output: Contribution To Journal



Manoharan, A, Anderson, WJ & Lipworth, BJ 2013,

'Relationship of large and small airway response with inhaled corticosteroid to asthma control' Annals of Allergy, Asthma & Immunology, vol. 111, no. 2, pp. 140-142. DOI:
10.1016/j.anai.2013.05.017

Research output: Contribution To Journal



Short, PM, Williamson, PA, Anderson, WJ & Lipworth, BJ 2013,

'Randomised Placebo-controlled Trial to Evaluate Chronic Dosing Effects of Propranolol in Asthma' American Journal of Respiratory and Critical Care Medicine, vol. 187, no. 12, pp. 1308-1314. DOI:
10.1164/rccm.201212-2206OC

Research output: Contribution To Journal



Lipworth, BJ, Basu, K, Donald, HP, Tavendale, R, Mac Gregor, DF, Ogston, SA, Palmer, CNA & Mukhopadhyay, S 2013,

'Tailored second-line therapy in asthmatic children with the Arg16 genotype' Clinical Science, vol. 124, no. 8, pp. 521-528. DOI:
10.1042/CS20120528

Research output: Contribution To Journal



Lipworth, B 2013,

'Targeting the small airways asthma phenotype: if we can reach it, should we treat it?' Annals of Allergy, Asthma & Immunology, vol. 110, no. 4, pp. 233-239. DOI:
10.1016/j.anai.2013.02.009

Research output: Contribution To Journal



Lipworth, BJ 2013,

'Adrenal suppression with fluticasone furoate' Annals of Allergy, Asthma & Immunology, vol. 110, no. 3, pp. 213. DOI:
10.1016/j.anai.2012.12.009

Research output: Contribution To Journal



Manoharan, A, Anderson, WJ & Lipworth, BJ 2013,

'Influence of β2-adrenergic receptor polymorphism on methacholine hyperresponsiveness in asthmatic patients' Annals of Allergy, Asthma & Immunology, vol. 110, no. 3, pp. 161-164. DOI:
10.1016/j.anai.2012.12.019

Research output: Contribution To Journal



Anderson, WJ, Lipworth, BJ, Rekhraj, S, Struthers, AD & George, J 2013,

'Left Ventricular Hypertrophy in COPD Without Hypoxemia: The Elephant in the Room?' CHEST, vol. 143, no. 1, pp. 91-97. DOI:
10.1378/chest.12-0775

Research output: Contribution To Journal



Williamson, PA, Short, PM, Vaidyanathan, S & Lipworth, BJ 2013,

'Inhaled and Systemic Corticosteroid Response in Severe Asthma Assessed by Alveolar Nitric Oxide: a randomised crossover pilot study of add-on therapy' British Journal of Clinical Pharmacology, vol. 75, no. 1, pp. 93-102. DOI:
10.1111/j.1365-2125.2012.04319.x

Research output: Contribution To Journal



Lipworth, BJ & Short, P 2013,

'Explaining differential effects of tiotropium on mortality in COPD' Thorax, vol. 68, no. 6, pp. 589-590. DOI:
10.1136/thoraxjnl-2012-203176

Research output: Contribution To Journal



Lipworth, B, Manoharan, A & Short, P 2012,

'Tiotropium in asthma' New England Journal of Medicine, vol. 367, no. 26, pp. 2552. DOI:
10.1056/NEJMc1213076

Research output: Contribution To Journal



Anderson, WJ, Short, P, Williamson, PA & Lipworth, BJ 2012,

'Inhaled corticosteroid dose response using domiciliary exhaled nitric oxide in persistent asthma: the FENOtype trial' CHEST, vol. 142, no. 6, pp. 1553-61. DOI:
10.1378/chest.12-1310

Research output: Contribution To Journal



Short, P, Williamson, PA & Lipworth, BJ 2012,

'Sensitivity of impulse oscillometry and spirometry in beta-blocker induced bronchoconstriction and beta-agonist bronchodilatation in asthma' Annals of Allergy, Asthma & Immunology, vol. 109, no. 6, pp. 412-5. DOI:
10.1016/j.anai.2012.09.010

Research output: Contribution To Journal



Short, PM, Williamson, PA & Lipworth, BJ 2012,

'Effects of Extra-Fine Inhaled and Oral Corticosteroids on Alveolar Nitric Oxide in COPD' Lung, vol. 190, no. 4, pp. 395-401. DOI:
10.1007/s00408-012-9378-8

Research output: Contribution To Journal



Anderson, WJ, Mc Farlane, LC & Lipworth, BJ 2012,

'Prospective Follow-Up of Novel Markers of Bone Turnover in Persistent Asthmatics Exposed to Low and High Doses of Inhaled Ciclesonide over 12 Months' Journal of Clinical Endocrinology & Metabolism, vol. 97, no. 6, pp. 1929-1936. DOI:
10.1210/jc.2011-3410

Research output: Contribution To Journal



Short, PM, Williamson, PA & Lipworth, BJ 2012,

'Effects of hydrocortisone on acute β-adrenoceptor blocker and histamine induced bronchoconstriction' British Journal of Clinical Pharmacology, vol. 73, no. 5, pp. 717-726. DOI:
10.1111/j.1365-2125.2011.04143.x

Research output: Contribution To Journal



Anderson, WJ & Lipworth, BJ 2012,

'Does body mass index influence responsiveness to inhaled corticosteroids in persistent asthma?' Annals of Allergy, Asthma & Immunology, vol. 108, no. 4, pp. 237-242. DOI:
10.1016/j.anai.2011.12.006

Research output: Contribution To Journal



Vaidyanathan, S, Williamson, P & Lipworth, B 2012,

'Comparative evaluation of nasal blood flow and airflow in the decongestant response to oxymetazoline' Annals of Allergy, Asthma & Immunology, vol. 108, no. 2, pp. 77-80. DOI:
10.1016/j.anai.2011.11.013

Research output: Contribution To Journal



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