16 Oct 2019

Dundee academic among BBC '100 Women 2019'

Dr Sarah Martins da Silva, of the University of Dundee's School of Medicine, has been named on BBC’s '100 Women 2019' list of inspiring and influential women from around the world. The BBC list asks 'What would the future look like if it were driven by women?' and features globally–recognised names such as climate change activist Greta Thunberg and footballer Megan Rapinoe among many others. Dr da Silva, who is Senior Lecturer in Reproductive Medicine, runs a translational research programme focused around male infertility, sperm biology and drug discovery. She said, “I hope that we can h...

Dundee academic among BBC '100 Women 2019'

15 Oct 2019

Blood test raises hopes of tackling ‘silent killer’

It is the ‘silent killer’ that claimed the life of Albert Einstein and affects 1% of men over the age of 65, but researchers at the School of Medicine believe they may be able to reduce the number of fatalities caused by abdominal aortic aneurysms. Aneurysms are the swelling and weakening of the arterial wall. Aortic aneurysms occur in the aorta, which delivers blood from the heart to organs. Aneurysms are often called a silent killer, because patients can display no symptoms until the aneurysm bursts. Around 80% of all patients with a ruptured aneurysm die from the condition. A team from the S...

Blood test raises hopes of tackling ‘silent killer’

21 Aug 2019

Lung bacteria “feign pregnancy” to avoid detection

Disease-causing bacteria in the lung evade the body’s immune system by pretending the lungs are pregnant, according to University of Dundee research presented today at the European Respiratory Society Congress in Madrid. A new study, funded by the British Lung Foundation and the Scottish Government’s Chief Scientist Office, has revealed that people with two common lung diseases – COPD and bronchiectasis – produce Pregnancy Zone Protein (PZP) in their lungs when they have a chest infection. Both men and women can produce small amounts of PZP, but it is produced at much higher concent...

Lung bacteria “feign pregnancy” to avoid detection

21 Aug 2019

Forgotten cancer to be tackled by School scientists

The University of Dundee is to lead new research into a ‘forgotten cancer’ related to lifestyle and deprivation which Scots are more likely to be diagnosed with than almost any other group in the world. Russell Petty, Professor of Medical Oncology at the School of Medicine, has received £300,000 from the Chief Scientist Office to try and overcome resistance to treatment experienced by oesophageal squamous cell carcinoma (OSCC) patients. The problem of resistance is so serious that 60% of people die within a year of being diagnosed and only around 15% of patients are cured. While oesophage...

Forgotten cancer to be tackled by School scientists

21 Aug 2019

‘Yin and yang’ enzymes evolve over billions of years to help protect against cancer

Researchers at the School of Medicine have made an important discovery about two enzymes that have evolved over billions of years to control many different bodily functions, including playing a critical role in preventing cancer. The team, led by Dr Adrian Saurin, investigated the enzymes PP1 and PP2A which were known to be vital to the process of cell division, although the precise role they played has puzzled scientists until now. Cell division, also known as mitosis, sees a parent cell divide into two daughter cells containing the same DNA content. If this process goes wrong, and the DNA is not partitio...

‘Yin and yang’ enzymes evolve over billions of years to help protect against cancer