' AMPK phosphorylation of FNIP1 dictates the kinetics of lysosome and mitochondrial biogenesis’

Host: Philip Cohen 

Location: CTIR 284 (Sir Kenneth and Lady Noreen Murray Seminar room) , SLS 

Bio: 

Nazma Malik obtained a B.Sc in Life Sciences from the University of Durham and the Open University in 2009 and an M.Sc in Medical and Molecular Sciences from the University of Newcastle in 2011, before accepting an MRC Studentship to carry out her PhD in the MRC Protein phosphorylation and Ubiquitylation Unit in Dundee in 2013 from where she obtained a PhD degree in 2017 under the supervision of Dario Alessi for a Thesis entitled ‘Novel Insights into the Regulation and Function of the Serum and Glucocorticoid Activated Kinase 3 (SGK3), where she elucidated the molecular mechanisms by which growth factors activate SGK3 via Class I and Class III phosphatidyl inositol 3 kinases. She also published a first authored paper entitled “Suppression of interferon β gene transcription by inhibitors of bromodomain and extra-terminal (BET) family members” for studies that she carried out during a first year PhD rotation project in Philip Cohen’s Lab. Since 2018 she has been carrying out postdoctoral research in Reuben Shaw’s lab at the Salk Institute, California where she has made important discoveries about the molecular mechanism by which the AMP-activated protein kinase controls gene transcription, which the topic of her seminar today. Outside of science, Nazma is also interested in history and languages, which she has pursued by travelling extensively throughout the world learning languages along the way. She is fluent in Bengali, Hindi, Urdu, French and written Arabic, but her seminar will be presented in English!