Research and Innovation Services : University of Dundee, Scotland, UK

Researchers at the University of Dundee have established a novel, highly efficient gene silencing system known as snoMEN^®1. Application of this technology to the field of cancer has led to the ground breaking discovery of molecules capable of targeting micro RNA precursors (pri-/pre-miRNA) associated with disease.

Researchers at the University of Dundee have established a transgenic mouse model of psoriasis which recreates the main characteristics of human psoriasis in vivo. The model is suitable for pre-clinical drug discovery and is available on a fee-for-service basis.

Researchers at the University of Dundee have established a novel, highly efficient gene silencing system known as snoMEN^®1. Application of this technology to the field of cancer has led to the ground breaking discovery of molecules capable of targeting micro RNA precursors (pri-/pre-miRNA) associated with disease.

Researchers at the University of Dundee have designed and synthesised a novel, multifunctional protease inhibitor which effectively attenuates multiple endo/lysosomal proteases.   Intended to overcome the problem of redundancy with this class of drugs, the new molecule represents a significant advance with far-reaching therapeutic potential.

Researchers at the University of Dundee have identified a novel and important component of a central tumor suppressor pathway. This discovery has the potential to impact upon the detection and development of novel treatments for a wide range of cancers and other disorders.

A program for generating molecular topologies and unique molecular descriptors from coordinates of small molecules. Rapid Licence - non-exclusive software licence - cost: £500 + VAT.

The unit represents an integrated professional, industry standard, drug discovery facility to translate basic biomedical research into potential new therapies through the discovery and patenting of novel pre-clinical leads and candidate small molecules.