Carlos Andrés Mugruza Vassallo
Postgraduate Student

Contact Details:
Email: Carlos Andrés Mugruza Vassallo
Telephone No: (+44)(1382) 384926
Postal Address:
School of Psychology
The University of Dundee
Dundee
DD1 4HN
Scotland, UK
Supervisor: Douglas Potter
Co-supervisors: Guillaume Rousselet (University of Glasgow), Cyril Pernet (University of Edinburgh)
Current research: Spatial and temporal imaging of attention reorienting mechanisms
http://www.sinapse.ac.uk/phdprojects/mugraza-phdproject.pdf
Interests
General: Understand at different levels computations in cognitive-dynamic mechanisms.
Specific and current: Study dynamics in attention. Currently, I am finishing with the analysis of orienting responses in controls and schizophrenic data in an oddball number decision parity task. The idea was to study functional imbalance of activity levels in attention reorienting networks between the left and right hemisphere with general linear model in EEG. Moreover, we have found the stimulus properties are strongly marking some feature in the P3a wave. Because of this, we have set up a simultaneous EEG fMRI to find the areas activated when particular activation of P3a are on a particular period of time. And more recently we are playing with temporal stimulus properties to study the boundary between alerting and orienting of attention. So, I'd like to understand how brain areas/networks are involved in reorienting attention mechanisms and specifically, temporal and spatial brain mechanisms and have a better dynamic insight in the theories of attention.
Biography
I have born in Huacho (Peru), near to possibly the oldest city in America (see at http://www.caralperu.gob.pe/nueva/civilizacion_ing.htm ). When I was child I won some mathematic competitions (at that time I felt admiration by Greek mathematics and Leonardo Da Vinci). Subsequently, as a result of reading biographies of Leeuwenhoek and Newton I became interested in applying my math skills to scientific questions. Later, I move to Lima to study electronic systems and I obtained a First class honours degree in Electronic Engineering. Then, I became involved in the development of medical equipment (see GIDEMS group at www.pucp.edu.pe/grupo/gidems/ ) modelling and I designed a sensor and some experiments in pneumatic pipes to be used in respiratory devices. My main contribution was to insert thermodynamics and compressibility of the gas to make the analysis. I enjoyed working in this large research group to develop a respiratory device, and collectively we develop a new flow sensor (patent granted). After, I studied computational neuroscience in Sao Paulo (Brazil, see LEB at http://www.leb.usp.br/ ), I obtained a graduate degree (Master Science degree with GPA 3,9 of 4,0) while I became involved in a dissertation about modelling motor unit action potentials, and I worked also geometry and mathematics to model the motor units (i.e. the motoneuron when innervate a group of muscle fibers and how it could be recording), we took some recording and I used the data to produce a theoretical model (in which my main contribution was to insert spatial geometry at muscle fiber analysis, that I thought mainly in a short Christmas vacations). Later, I went to Peru to work 2 years in the Peruvian Patent Office as a patent examiner, in the technical examination of G and H international patent classifications, to pay my previous studies. From there, I produced reports in this time, one of them was about Patents in Neuroscience (presented at ECI 2009 conference), the finding is that schizophrenia and Alzheimer disease is the most subjects granted in patents of Neurobiology, at least in the patent offices at US (USPTO), Europe (EPO) and Peru (INDECOPI). Now, I am starting to study the brain at theoretical and experimental level with cognitive electrophysiology and neuroimaging (see SINAPSE at http://www.sinapse.ac.uk/phdprojects/mugraza-phdproject.pdf ) with Douglas Potter (Dundee), Cyril Pernet (Edinburgh), and Guillaume Rousselet (Glasgow). I am interested in the development of new biomarkers of cognitive function in Schizophrenia as well as other disorders such as depression and mild cognitive impairment, providing a better understanding of the role of the stimulus-driven system in switching between goal-driven and default processing modes. Currently, I have started to study the processes involved attention mechanisms and multi-modal imaging inference, and with this basis we expect to make up experiments and model one reorienting attention mechanism.
Publications – Conference Posters
- MUGRUZA VASSALLO, C.A., POTTER, D.D., PERNET, C., ROUSSELET, G.A. (2011). "Analysis of predictors based on stimulus properties influencing P3a amplitudes in an auditory attention orienting task". SINAPSE Annual Scientific Meeting 2011, pp. 10. Dundee, 2011
- MACFARLANE, J.A.; POTTER, D.D.; MUGRUZA VASSALLO, C.; TSIORA, S.; CAVIN, I.D.; LERKSI, R.A.; CROWE, E.; KANODIA, A.K (2011) "Do fluctuations in EEG measures recorded during a verbal working memory task systematically predict short-term changes in simultaneously acquired fMRI BOLD responses? " SINAPSE Annual Scientific Meeting 2011, pp. 19 Dundee, 2011
- MAXWELL, A.M., POTTER, D.D.; MACFARLANE, J.A.; CAVIN, I.D.; TSIORA, S.; MUGRUZA VASSALLO, C.; LERKSI, R.A.; CROWE, E.; KANODIA, A.K(2011) "Investigating the dynamic relationship between fMRI measures of default mode network (DMN) activity and EEG measures of DMN". SINAPSE Annual Scientific Meeting 2011 proceeding, pp. 17 Dundee, 2011
- POTTER, D.D.; MACFARLANE, J.A.; CAVIN, I.D.; TSIORA, S.; MUGRUZA VASSALLO, C.; MCINALLY, S.; LERKSI, R.A.; CROWE, E.; KANODIA, A.K (2010). "Initial experience of combined EEG fMRI development work at 3 T". Poster in SINAPSE Annual Scientific Meeting - Recent Developments in Brain Imaging, Royal Society of Edinburgh, June 16th 2010.
- MUGRUZA VASSALLO, C.A., POTTER, D.D., PERNET, C., ROUSSELET, G.A. (2010). "Developing paradigms for a combined EEG fMRI study: An exploration of factors influencing P3a amplitude in an auditory attention orienting task". Poster in Symposium: Motivational and Cognitive Control, Oxford, June 2-4, 2010
Publications – Conference Papers
- MUGRUZA VASSALLO, C.A. "Patentes de neurociencias: desde la biotecnología hasta la bases de datos de patentes". In CONIIC proceedings pp1-4, October 22-24, 2008, Lima, Peru.
- MUGRUZA VASSALLO, C.A.; KOHN, A.F. "Simulation Of The Spatial Distribution Of Muscle Fibers Within The Motor Unit Territory In Cats. In: 8th International Bioinformatics Conference. June 15,2006. Århus, Denmark
- MUGRUZA VASSALLO, C.A.; KOHN, A. F. . Modelagem e simulação da distribuição das fibras musculares em uma unidade motora. In: XX Congresso Brasileiro de Engenharia Biomédica, 2006, São Pedro. Anais em CD-ROM, 2006. p. 1506-1509.
- MUGRUZA VASSALLO, C.A. Van der Waals and Ideal gas models for compressibility by means of pressure in pneumatic pipes from 1 to 100 Lpm. In: 26th Annual International Conference of the engineering in Medicine and Biology Society, 2004, 2004, San Francisco. Proceedings of the 26th Annual International Conference of the IEEE EMBS, 2004. v. 1. p. 2034-2037.
- MUGRUZA VASSALLO, C.A.; LANDEO, C.A.R. Resultados de la calibración del modo de control por volumen continuo para Ventiladores Pulmonares en una UCI. In: I Congreso Internacional de Fisiología y Fisiopatología, 2003, Trujillo. Resumos del I Congreso Internacional de Fisiología y Fisiopatología, 2003.
- MUGRUZA VASSALLO, C.A.; GALLARDO, R.V. Transductor de flujo de gases basado en un tubo de Venturi, rango de 2 hasta 70 Lpm. In: Tercer Congreso Iberoamericano de Sensores y Biosensores, 2002, Lima, 2002. p. 23-28.
- MUGRUZA VASSALLO, C.A. Sensor y transductor de Flujo de Gases de Hilo Caliente de una aleación Níquel–Titanio de menos de 200 Lpm. In: Tercer Congreso Iberoamericano de Sensores y Biosensores, 2002, Lima, 2002. p. 122-126
- MUGRUZA VASSALLO, C.A ; LANDEO, C.A.R. Sistema de medición de flujo volumétrico basado en compliancia constante de hasta 100 Lpm. In: Tercer Congreso Iberoamericano de Sensores y Biosensores, 2002, Lima, 2002. p. 157-159.
- MUGRUZA VASSALLO, C.A. Transductor de Flujo de Gases Basado en Hilo Caliente. In: XI Congreso Internacional de Ingenieria Electrónica, Comunicaciones y Computadoras, 2001, Puebla. CONIELECOMP'2001, 2001. p. 136-140.
- MUGRUZA VASSALLO, C.A ; VASSALLO, A.A.C. Estimulador Electrico Neuromuscular. In: XI Congreso Internacional de Ingenieria Electrónica, Comunicaciones y Computadoras, 2001, Puebla. CONIELECOMP 2001, 2001. p. 36-40.
- MUGRUZA VASSALLO, C.A. ; CARRERA SORIA, W.. Tranductor de flujo de gases basado en hilo caliente de aleación Níquel - Titanio. In: II Congreso Latinoamericano de Ingeniería Biomédica, 2001, La Habana. Memorias II Congreso Latinoamericano de Ingeniería Biomédica, 2001.
- MUGRUZA VASSALLO, C.A. Flow gas transducer on basis of a hot wire with a nickel-titanium alloy in its flow calibration system. In: Engineering in Medicine and Biology Society, 2001, 2001, Istambul. Proceedings of the 23rd Annual International Conference of the IEEE EMBS, 2001. v. 3. p. 3124-3127.
Publications – Non peer review journal
- MUGRUZA VASSALLO, C.A. Dinámica no lineal y caos en circuitos eléctricos de elementos pasivos R, C, diodo en serie: respuesta en frecuencia. Electro electrónica, v. 22, p. 12 - 15, 20 Julio. 2004.
- MUGRUZA VASSALLO, C.A. Modelos de gas Van der Waals y gas ideal para compresibilidad: por medio de presión para cambios de áreas en circuitos neumáticos de 1 a 100Lpm. Electro electrónica, v. 22, p. 07 - 11, 20 Julio. 2004.
- MUGRUZA VASSALLO, C.A ; VILLAVICENCIO, R. ; PALOMINO, A. Transductor de flujo de gases basado en un tubo de Venturi, rango de 2 hasta 70Lpm. Electro electrónica, v. 17, p. 46 - 53, 08 Enero. 2002.
- MUGRUZA VASSALLO, C.A. Sensor de flujo de gases basado en una aleación del Níquel con Titanio. Electro electrónica, v. 15, p. 48 - 52, 09 Enero. 2001.
Patent Applications
- MUGRUZA VASSALLO, C.A; CASTILLON LEVANO, C.B.; COELLO, J.L. "Neonatal Intensive Care Unit". PCT/IB2009-007014. Patent application filed in Korea on September, 2009.
Qualifications and Role
M.Sc. in Biomedical Engineering inside Telecommunication and Control Department at Electronic Systems at University of São Paulo (USP) – Dissertation Title: Mathematical modeling and simulation of motor unit action potentials. (Advisor: André Fabio Kohn) June 23, 2006 Master Degree in Electronic Systems with mention in Biomedical Engineering with GPA = 3,9 / 4,0
Professional degree
Undergraduate dissertation title: Analysis, design and testing of flow gases transducer (Advisor: Willy E. Carrera Soria) July 3, 2001 Degree in Electronic Engineer with Honours.
B.Sc. in Electronic Engineering at Pontifical Catholic University of Perú, Lima, Perú. (1995 - 2000)
Teaching
- (Sept 2009 - To Date) Level 3 Psychology demonstrator at the University of Dundee: Research Skills 3 (2009-10).
- (Sept, 2007 – April 2009) Teaching courses at Technological University of Peru (UTP). Undergraduate courses of Level 3 and 5 of Mechatronic Engineering and Electronic Systems
- Artificial Intelligence (from Jan 2009 to April 2009).
- Sensors and Actuators.
- Electromagnetic Field Theory for Engineering
- (Sept, 2007 – Oct, 2008) Level 4 Medical demonstrator at Cayetano Heredia Peruvian University (UPCH). Undergraduate course of 'Introduction to Neuroscience'.
- (Sept 2009 -) Level 3 Psychology demonstrator at the University of Dundeee: Research Skills 3 (Aug, 2000- Dec, 2003) Level 3 and 4 of Electronic Systems demonstrator at the Pontifical Catholic University of Peru (PUCP) Undergraduate courses of: Electronic Design Laboratory 1, Electrical Machines 1, Electrical Circuits 1.
Prizes and Funding
At the PhD in the University of Dundee:
- 2010 Mathematical Neuroscience Awarded contribution to participate in Mathematical Neuroscience Apr 19, 2010 - Apr 21, 2010 (Edinburgh, UK).
- 2009 Scholarship of IBRO to the Latin American Summer School in Computational Neuroscience and Biomedical Applications (LACONEU 2010, 120 hours) – Valparaiso, January 11-29, 2010. Project "Testing of a Prefrontal contex modeling based in minicolumns: The prefrontal cortex in an 'n' x 'm' maze and pathways selection" (Valparaiso, Chile).
- 2009-2012 Studentship from SINAPSE to follow the PhD project "Spatial and temporal imaging of attention reorienting mechanisms" in the University of Dundee
At the teaching at Technological University of Peru (UTP):
- 2008 Scholarship of IBRO to the III International Course on Neurobiology: Techniques for electrophysiological recording in neural preparations.
At the MSc in the University of Sao Paulo (USP):
- 2004 - 2006 Scholarship CAPES to follow studies in Biomedical Engineering at USP (Sao Paulo, Brazil).
At the teaching assistant at PUCP:
- 2003 3st place in Research Work Competition, I Congreso Internacional de Fisiología y Fisiopatología – Trujillo, Perú.
- 2002 "Cyclic Control System to DNA replication", which has being developed from March of 2002. This work has obtained the Second Place in the Annual Competition of Projects – INTERCON 2002 (International Congress on Electronics, Lima, IEEE2002-Perú).
- 2001 Winner research of "Research Annual Prize 2001" Teaching Category – "Analysis, design, simulation, built and calibration of a flow gases transducer of hot wire based on an Nickel-Titanium alloy whose range is between 1 and 100 Lpm and a flow calibration system of constant compliance - December 15th, 2001 – 1st place.
- Winner research of "Research Annual Prize 2001" Teaching Category – "Analysis, design, simulation and calibration of a flow gases transducer of hot wire based on Venturi's pipe - December 15th, 2001 – 2st place. http://www.pucp.edu.pe/investigacion/?apo_pre_gan.htm
At the university under-graduated: Bachelor degree at PUCP
- 2001 Winner on Investigation Competition GIDEMS 2001 with "Analysis, design, simulation, built and calibration of a flow gases transducer of hot wire based on an Nickel-Titanium alloy, April 6th, 2001.
- 1995 – 2000 Scholarship/Education Loan RVDO. PADRE JORGE DINTILHAC to follow studies in Electronic Engineering at PUCP (Lima, Perú).
At the high school:
- 1993 Winner of National Mathematical Olympic of the High School TRILCE – 1st place.
- 1993 Scholarship from C.E.P. San Isidro el Labrador (Lima, Perú).
- 1992 Winner of INTERNAL ECUDEM (Cultural Meet Mercedario) – 1st place.
- Winner of High School Regional Mathematical Competition (with one year lesser than another participants) , Mathematics, Physics and Chemistry – 1st place.
- Winner of Science Inter-School Departmental Competition ALFAMATICA – 1st place.
- 1991: Winner of INTERNAL ECUDEM (Cultural Meet Mercedario) Third year high school, Mathematics and Chemistry – 1st place.
- Winner of High School Regional Mathematical Competition (with two year lesser than another participants), Mathematics, Physics and Chemistry – 1st place.
- 1991 – 1992 Scholarship from Direction of C.E.N.E. Nuestra Señora de la Merced (Huacho, Perú).
Training Courses and Workshops
At the PhD in the University of Dundee:
- Training course: Edinburgh SPM Course 26th-29th April 2010. MATLAB software toolbox implementing Statistical Parametric Mapping for neuroimaging data.
- Training and Workshop: Mathematical Neuroscience Apr 19, 2010 - Apr 21, 2010, Edinburgh.
- Course: Latin American Summer School in Computational Neuroscience and Biomedical Applications (LACONEU 2010, 120 hours) – Valparaiso, January 11-29, 2010. Project developed with Thiago Rivero: "Testing of a Prefrontal contex modeling based in minicolumns: The prefrontal cortex in an 'n' x 'm' maze and pathway selection".
At the teaching at Technological University of Peru (UTP):
- Course: International Course on Neurobiology: Techniques for electrophysiological recording in neural preparations (40 hours) – Bogota, April 21-24, 2008
At the MSc in the University of Sao Paulo (USP):
- Course: Raman Molecular Spectroscopy (10 hours – Espectroscopia Molecular Raman) – Sao Paulo, July 17-21, 2006
- Course: Model and Biological Membranes (48 hours – Membranas Biológicas e Modelo) – Sao Paulo March - May, 2006 – S. Scheirier, C. Alvarez
- Course: Visualization of Cellular Traffic (9 hours – Visualización de Tràfico Celular) – T. Kirchhausen, Lima. January 03-05, 2006
- Course: Introduction to quantum mechanics (60 hours – Mecanica Quantica 1) – Sao Paulo August - November, 2005
- Course: Molecular Biotechnology (Biotecnología Molecular) – C.Bustamante, T. Kirchhausen, E. Malaga Trillo, A. Becerra, M. Milla., Lima January 06-09, 2004

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