Centre for Academic Clinical Practice
Centre for Primary Care & Population Research
Lead, Dr Fiona Williams
The Human Brain Development group is focused on early brain development. The overarching research aim is to optimise neurodevelopmental outcome of infants through the development of a range of preventative approaches. The research design we have developed to support our programme of work is integrated, international, inter-disciplinary and translational, and reflects the concept that prevention of cerebral damage comes from applications of the metabolic and molecular bases of human development.
Our research is focussed on the influences of specific conditions which impact on human postnatal brain development and to date has included hyperbilirubinaemia, hypoglycaemia and hypothyroxinaemia. The translation of our basic research to clinical application has proved robust and we are about to start a major UK multi-centre clinical trial to determine whether iodine supplementation of parenteral nutrition improves postnatal brain development. Our funding includes: MRC trial grant, NHS programme grants, Chief Scientist Office research grants and charities: Tenovus (Scotland), Anonymous Trust, Paediatric Research Fund, Cerebra.
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