Dr Paul Campbell

I was appointed to a Lectureship here in the Carnegie Laboratory for Physics in 2005. For the forthcoming academic year, I will be teaching the modules on Electricity & Magnetism (3rd Year) & Astronomical Phenomena (1st Year). My research interests are geared towards the exploitation of Physics, and associated technologies, in the context of Medicine. I am Principal Investigator on several externally funded research projects, and hold active research funding in excess of £1.4 million. I lead both the Biomedical Physics Group and the Undergraduate Research Group, presently comprising about a dozen staff & students.

The main thrust of my research revolves around the use of ultrasound to deliver therapeutic molecules in a non-invasive fashion. In pursuit of this, we try to understand the fundamental interactions of ultrasound with biological tissues and cells. This is an experimentally demanding project requiring direct observation of very dynamic microscopic entities, with sub-microsecond temporal resolution. Our initial data in this area was recently published in the highly rated journal, Nature - Physics.

I am also involved with the development of thermal imaging as an adjunct to energized surgery. This work is undertaken with the collaboration of the eminent surgeon, Professor Sir Alfred Cuschieri, and has recently realized development of the first practical infrared endoscope in Europe. We hope that further downstream prototypes may allow surgeons to undertake electrosurgical procedures with automated real-time selection of power levels, thus reducing collateral damage to patients that may otherwise go unnoticed.

The Undergraduate Research Group exists to promote direct application of the taught undergraduate syllabus to real world problems. Whilst there is some reliance on the available research infrastructure, projects are largely driven by student's own interests, and we have three currently active interdisciplinary projects relating to Homeland Security and Defence Science, and also hyper-spectral medical imaging.

• Higher Scientific Officer - Defence Research Agency (Farnborough)
• Postdoctoral Fellowships at the Universities of Bath (Materials Science) & Queen's Belfast (Probe Microscopy)
• Visiting Scholar - Georgia Institute of Technology, Atlanta (Ultrasound mediated drug delivery)
• Wellcome Trust Senior Research Fellow - Ninewells Hospital Dundee (Surgical Technology)

• Therapeutic Ultrasound, specifically Sonoporation
• Cavitation Physics
• Thermal Imaging as applied to Medicine and Defence
• Scanning Probe Microscopy
• Intelligent drug delivery
• Exploitation of Optical Trapping as a tool in Biophysical metrology

• Membrane disruption by optically controlled microbubble cavitation. Nature Physics 1, 107 (2005)
• Thermography in Surgery. Chapter 33 in the CRC Biomedical Engineering Handbook (2006)
• Site occupancy of chlorine on Cu(111) using NIXSW Physical Review B 70 (15) #155409 (2004)
• Future Directions for Therapeutic Ultrasound. Ultrasound in Medicine and Biology 33, 657 (2007)
• Optical trapping and manipulation of single and multiple contrast agent micro-bubbles Optics Express 12 (4) 593 (2004)

Dr Paul Campbell

Division of Electronic Engineering and Physics

University of Dundee

Nethergate

Dundee

DD1 4HN