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Craniofacial Anomalies Research Group

The research activities include the following

• The Unit of Dental and Oral Health at the University of Dundee Dental School was designated a WHO Collaborating Centre for Public Health Issues on Congenital Anomalies and Technology Transfer in August 2004, and in July 2010 this has been re-designated for a further four years.
• Orofacial clefting (OFC) research: the combined influence of environment and genotype and the role of heredity in orofacial clefts: in particular analysis of maternal medical factors, nutrition, lifestyle and occupation, and biochemical markers of nutrition for primary prevention.
• Eurocran project produced, by pan European collaboration, the world’s largest single trios biobank (1190 CL/P trios from 8 different countries)
• Collaboration on recent breakthroughs in genetics of CL(P), with a series of publications appearing in Nature Genetics.
• Collaborative OFC research with a global and health inequalities perspective, involving developing world countries such as India, Nepal, Brazil and Nigeria.
• Evidence-based craniofacial and orthodontic care through Cochrane reviews and developing new evidence through a cohort of related clinical trials.
• Collaboration with external colleagues across the UK and Ireland through the Clinical Orthodontic Research Consortium, currently submitting for funding a feasibility study to address the issue of tooth extraction in orthodontic treatment.