Prof Sam Eljamel

Research

Research Interests:

My research is in three main domains:

1. Stereotaxy, robotics, image guidance and functional neurosurgery in the field of deep brain stimulation for movement disorders, mental disorders, epilepsy and chronic pain. Selected papers are listed here;

• Eljamel MS. Validation of a neurosurgical robot using a phantom. Int J Med Robotics Comput Assist Surg 2007; 3:372-7.
• Eljamel MS, Tulley M, Spillane K. A simple stereotactic method for frameless deep brain stimulation. Stereot Funct Neurosurg 2007; 85: 6-10.
• Eljamel MS, Robotic applications in epilepsy surgery. Int J Med Robot. 2006; 2(3): 233-237.
• Eljamel MS, Hofer M. From Letterbox to Keyhole Approach for Resecting Intracranial Lesions, Stereot Funct Neurosurg, 2004; 81: 30- 36.
• Eljamel MS. Frameless Stereotactic Neurosurgery: Two Steps towards the Holy Grail of surgical navigation. Stereotact Funct Neurosurg; 1999; 72(2-4): 125-128
• Eljamel MS. Accuracy, efficacy and clinical applications of the Radionics Operating Arm System. Comput Aided Surg 1997; 2(5): 292- 297
• Eljamel MS. Ablative neurosurgery for mental disorders: is there still a role in the 21st century? A personal perspective. Neurosurg Focus. 2008;25(1):E4.
• Haridas A, Mathewson C, Eljamel S. Long-term results of 405 refractory trigeminal neuralgia surgeries in 256 patients. Zentralbl Neurochir. 2008;69:170-174.
• Steele JD, Christmas D, Eljamel MS, Matthews K. Anterior Cingulotomy for major depression: clinical outcome and relationship to lesion characteristics. Biological Psychiatry 2007; 63:670-7.
• Christmas D, Curran S, Matthews K, Eljamel MS. Neurosurgery for mental disorders: vagus nerve stimulation and deep brain stimulation. Psychiatry Psychiatric Treatment 2006; 5-6: 212- 216.
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2. Neuro-oncology and Photodynamic Therapy , selected publications as follows:

• Eljamel MS, Goodman C, Moseley H. ALA and Photofrin(R) Fluorescence-guided resection and repetitive PDT in glioblastoma multiforme: a single centre Phase III randomised controlled trial. Lasers Med Sci. 2008; 23:361-367.
• Moseley H, McLean C, Hockaday S, Eljamel S. In vitro light distributions from intracranial PDT balloons. Photodiagnosis and Photodynamic Therapy 2007; 4: 213- 220.
• Eljamel M Sam, Brain PDD and PDT unlocking the mystery of malignant gliomas. Photodiagnosis and Photodynamic therapy 2005; 1: 303- 310.
• Eljamel M S, Photodynamic assisted surgical resection and treatment of malignant brain tumours technique, technology and clinical application. Photodiagnosis and Photodynamic therapy 2004; 1: 93- 98.
• Eljamel MS. New Light on the Brain: The Role of Photosensitising Agents and Laser Light in the Management of Invasive Intracranial Tumours. Technol Cancer Res Treat 2003; 2(4): 303- 309.

3. CSF leaks and skull base: selected papers.

• Eljamel MS, Pidgeon CN, Toland J, Phillips JB, O'Dwyer A. MRI-Cisternography in CSF Fistulae localisation. Br J Neurosurg 1994; 8(4): 433- 437.
• Eljamel MS. Antibiotic prophylaxis in CSF fistulae. Br J Neurosurg 1993; 7(5): 501- 506
• Eljamel MS, Waring DJ. The Paragon Immunofixation for CSF identification. Biomed SCI 1993; 4 (2): 43- 45
• Eljamel MS, Foy PM. Non-traumatic CSF fistulae: clinical history and management. Br J Neurosurg 1991; 5(3): 275 – 79
• Eljamel MS. The role of Surgery and B2-Transferrin in the management of CSF Fistulae. MD. Thesis, Eljamel MS. Liverpool University, 1991 (THESIS).
• Eljamel MS. Foy PM. Acute Cerebrospinal fluid fistulae, the risk of intra-cranial infections. Br J Neurosurg 1990; 4(5): 381- 385
• Eljamel MS. Foy PM. Post-traumatic CSF Fistulae, the case for surgical repair. Br J Neurosurg 1990; 4(6): 479 – 483