Centre Member |
Research Interests |
Prof.
Frank Gunn-Moore
Centre Co-ordinator
Professor of Molecular Neurobiology
School of Biology
University of St. Andrews |
The ABAD-CypD-amyloid complex, a novel model for AD.
The growth and survival of mammalian neurones.
Biophotonics: the novel use of lasers in the transfection and manipulation of mammalian cells.
|
Dr.
James Ainge
RCUK Fellow, School of Psychology and Neuroscience
Institute of Behavioural and Neural Sciences
University of St. Andrews |
Learning and memory from a systems
perspective. Specifically in the neural basis of spatial and episodic
memory and how these processes decline in Alzheimer's disease. |
Dr.
Norman Alm
Honorary Research Fellow, School of Computing,
University of Dundee |
Possible applications of communication
and information technology to assist people with dementia. |
Prof.
Mike Ashford
Head of Division of Cardiovascular and Diabetes Medicine
University of Dundee |
BACE1 activity and the regulation of
metabolism. |
Dr.
Arlene Astell
Senior Lecturer, School of Psychology & Neuroscience
University of St. Andrews |
Cognitive neuropsychological investigation of language &
memory in Alzheimer's disease (AD).
The maintenance of preserved functioning & social participation in people with AD.
Assessment of capacity & decsion making in AD.
|
Dr.
Vassilios Beglopoulos
Senior Postdoctoral Fellow
Centre for Cognitive and Neural Systems
University of Edinburgh |
Memory encoding, consolidation and
retrieval in models of Alzheimer¹s disease and underlying brain
metabolic alterations. |
Dr. Peter Connelly
Consultant Old Age Psychiatrist
Chair, Scottish Dementia Clinical Research Network
peter.connelly@nhs.net
Dr.
Neil Prentice
Senior Lecturer in Psychiatry of Old Age
Consultant Old Age Psychiatrist |
The recognition of very early cognitive impairment in older people.
Predicting response to cholinesterase inhibitors.
Development of user and carer defined outcomes to pharmacological and non-pharmacological interventions.
The use of antipsychotic drugs for behaviour disturbance in people with severe dementia.
|
Dr.
Michaela Dewar
Research Fellow, Psychology
University of Edinburgh |
Anterograde amnesia. I am investigating
the role of retroactive interference in anterograde amnesia from
a cognitive as well as a neuroanatomical perspective. |
Dr.
Gayle Doherty
Research Fellow, School of Biology
University of St. Andrews |
Control of neuronal survival during development & ageing.
Special interest in factors that predispose individuals to neurodegenerative
conditions such as homocysteine.
|
Dr. Ashleigh Duthie
Consultant in Old Age Psychiatry
Royal Dundee Liff Hospital
ashleighduthie@nhs.net |
Use of antidementia medications in Scotland: Views of Old Age Psychiatrists
Non-psychiatric comorbidity associated with Alzheimer's disease
|
Dr. David Findlay
Consultant Psychiatrist
Royal Dundee Liff Hospital
david.findlay@nhs.net |
Provides Old Age Psychiatry to East Dundee and to the Dundee Memory Clinic.
Served on the Data Monitoring and Ethics Committee for the UK-wide CALM-AD study.
Currently a principal investigator in DOMINO-AD, a multi-centre
trial, this time of donepezil and memantine in AD.
Tayside Clinical Lead for the Scottish Dementia Clinical Research Network.
|
Dr.
Jill Fowler
Alzheimer’s Society Research Fellow,
Centre for Cognitive and Neural Systems,
University of Edinburgh |
The mechanisms that contribute to acute brain injury and why
these can may lead to neurodegenerative diseases such as AD.
The mechanistic role of inflammation and white matter pathology
in causing brain degeneration.
|
Prof. Ann Graham
Professor of Vascular Cell Biology
School of Health and Life Sciences
Glasgow Caledonian University
|
Intracellular cholesterol transporters: studies on their therapeutic potential for preventing amyloidogenesis and Alzheimer's Disease. |
|
Dr.
Jenni Harvey
Wellcome University Senior Lecturer
Division of Neuroscience
University of Dundee |
Hippocampal synaptic function in health and disease.
Role of leptin in neurodegenerative disorders.
|
Dr.
Sheriar Hormuzdi
Lecturer
Division of Neuroscience
University of Dundee |
Aberrant gap junction-mediated cellular
signalling as a catalyst for the development of neurological diseases. |
Prof.
Karen Horsburgh
Professor in Neuroscience,
Centre for Neuroregeneration,
The Medical School,
University of Edinburgh
|
White matter integrity and its contribution to cognitive decline
in normal ageing and Alzheimer's disease.
Brain injury and vascular dysfunction on cognitive decline and link to Alzheimer’s disease.
Apolipoprotein E4 as a common genetic susceptibility factor.
|
Dr. Fiona Kelly
Lecturer in Dementia Studies
School of Applied Social Science
University of Stirling
|
Looking at the organisational culture of care in care homes and how this facilitates or hinders good dementia practice.
An audit of service delivery to people with dementia and their families in Cumbria.
A knowledge exchange project to support professionals and practitioners to support family carers of people with dementia in Lothian.
|
Prof.
Timothy Kelly
Professor of Social Work
School of Education, Social Work and Community Education, University
of Dundee |
Supporting carers.
Supporting people with dementia at home.
|
Prof.
Jeremy Lambert
Professor
Division of Neuroscience
University of Dundee |
Neurosteroids, General Anaesthetics
and GABAergic neurotransmission, Huntington's disease |
Dr.
Stephen Land
Senior Lecturer,
Division of Cardiovascular and Diabetes Medicine
University of Dundee
|
Growth factor signaling and neuron survival responses
The link between BACE1, sprouty proteins and TrkB signalling
Regulation of the neural genome by Sprouty 2 and 4
|
Dr.
Rosamund Langston
Lecturer in Behavioural Neuroscience
Division of Neuroscience
University of Dundee |
Using novel developmental animal models
of memory combined with behavioural and in vivo pharmacological
and electrophysiological techniques to pinpoint critical structures
for episodic memory in the mammalian brain in health and disease. |
Dr. Susan Logie
Consultant in Old Age Psychiatry
Sunnyside Royal Hospital, Montrose
susanlogie@nhs.net |
Consultatnt in Old Age Psychiatry for
Forfar, Kirriemuir and South West Angus. |
Prof.
Jean Manson, OBE FRSE
Neuropathogenesis Division
The Roslin Institute
University of Edinburgh and R(D)SVS Roslin |
Works on both acute and chronic neurodegeneration
with particular interest in prion diseases and more recently Alzheimer's
Disease. |
Dr. Louise McCabe
Lecturer in Dementia Studies
School of Applied Social Science
University of Stirling
|
People with dementia and associated policy and practice issues. |
Prof.
Richard Morris CBE, FRS
Royal Society/Wolfson Professor of Neuroscience
Centre for Cognitive and Neural Systems
University of Edinburgh |
Memory encoding, consolidation and
retrieval in models of Alzheimer¹s disease and underlying brain
metabolic alterations. |
Dr.
Miratul Muqit
Wellcome Intermediate Clinical Fellow,
Clinical Lecturer in Neurology
MRC Protein Phosphorylation Unit,
University of Dundee |
Biochemical: Elucidation of signal
transduction networks in neurodegenerative diseases with a particular
interest in kinases mutated in disease.
Clinical: clinico-molecular characterisation of patients with
early-onset neurodegenerative disorders. |
Dr.
Carlos Penedo
Research Fellow
School of Physics & Astronomy
University of St Andrews |
Investigation of amyloid aggregation
pathways using single-molecule spectroscopy techniques.
Development of new fluorescence sensors for amyloid polymorphism.
Understanding the interaction between different amyloid aggregates and cellular membranes. |
Dr. Iris Oren
Centre for Cognitive and Neural Systems
University of Edinburgh |
Mechanisms of neuronal network dysfunction in early AD pathology. |
Prof. Emma Reynish
Consultant Physician - Victoria Hospital Kirkcaldy
Coordinator of the European Alzheimer's Disease Consortium
emma.reynish@nhs.net |
EUROCODE project - looking at the prevalence of Dementia in
Europe.
ICTUS project-natural history of AD in Europe.
Health services research looking at the improvement of the management
of patients with cognitive impairment in the acute hospital
setting.
|
Dr. Cesar Rodriguez
Consultant in Old Age Psychiatry
Sunnyside Royal Hospital, Montrose
crodriguez@nhs.net |
Pychopharmacology & Dementia. |
Dr. Margaret Semple
Consultant in Old Age Psychiatry
Royal Dundee Liff Hospital
margaret.semple@nhs.net |
Provides Old Age Psychiatry input to
Central East Dundee. |
Dr.
John Sharkey
Senior Lecturer
Division of Neuroscience
University of Dundee |
Molecular mechanisms underlying degenerative
brain disease with a particular interest in stress responsive
pathways in early Alzheimer's disease. |
Prof.
Susann Schweiger
Professor
Division of Neuroscience
University of Dundee |
The MID1 / PP2A protein complex: Novel
roles of a microtubule-associated ribonucleoprotein complex in
the pathogenesis of neurodegeneration: hope for unexpected therapeutic
avenues in Alzheimer's Disease and Huntingtin Chorea? |
Dr.
Alan Stewart
Lecturer in Molecular Medicine
School of Medicine
University of St Andrews |
Metal ion transport and homeostasis.
Calcium signalling in neurons and neuroendocrine cells. |
Dr.
Caroline Stewart
Lecturer
Division of Neuroscience
University of Dundee |
Factors affecting the initiation and
progression of Alzheimer's disease: the role of stress and diet. |
Dr.
Calum Sutherland
Reader
Division of Cardiovascular & Diabetes Medicine
University of Dundee |
Insulin signalling and disease - A
link between Diabetes and Alzheimer's? |
Dr. Shona Walker
Consultant in Old Age Psychiatry
Royal Dundee Liff Hospital
shonawalker@nhs.net |
Provides Old Age Psychiatry input to Central East Dundee.
Training Programme Director for the Old Age Psychiatry Scheme
in the East Deanery.
Involved in the Long Term Treament & Rehabilitation Group
and also in planning for a new facility for the Continuing Care
Funtional patient group in Dundee.
|
Dr. Joyce Yau
Endocrinology Unit,
Queen's Medical Research Institute
University of Edinburgh |
The role & regulation of 2 enzymes
in brain that control local steroid actions & their link with
cognitive decline with ageing. |
